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    PPa4 pyrophosphorylase 4 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 824530, updated on 18-Sep-2024

    Summary

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    Official Symbol
    PPa4
    Official Full Name
    pyrophosphorylase 4
    Primary source
    TAIR:AT3G53620
    Locus tag
    AT3G53620
    See related
    Araport:AT3G53620
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    AtPPa4; pyrophosphorylase 4
    Summary
    Encodes a soluble protein with inorganic pyrophosphatase activity that is highly specific for Mg-inorganic pyrophosphate.
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    Genomic context

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    See PPa4 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    9
    Sequence:
    Chromosome: 3; NC_003074.8 (19880504..19883743)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene C2H2-type zinc finger family protein Neighboring gene RAB GTPase homolog 8 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Protein kinase superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Vacuolar H(+)-Pyrophosphatase and Cytosolic Soluble Pyrophosphatases Cooperatively Regulate Pyrophosphate Levels in Arabidopsis thaliana. Segami S, et al. Plant Cell, 2018 May. PMID 29691313, Free PMC Article
    2. Virus-induced gene silencing of plastidial soluble inorganic pyrophosphatase impairs essential leaf anabolic pathways and reduces drought stress tolerance in Nicotiana benthamiana. George GM, et al. Plant Physiol, 2010 Sep. PMID 20605913, Free PMC Article
    3. bHLH05 is an interaction partner of MYB51 and a novel regulator of glucosinolate biosynthesis in Arabidopsis. Frerigmann H, et al. Plant Physiol, 2014 Sep. PMID 25049362, Free PMC Article
    4. Arabidopsis G-protein interactome reveals connections to cell wall carbohydrates and morphogenesis. Klopffleisch K, et al. Mol Syst Biol, 2011 Sep 27. PMID 21952135, Free PMC Article
    5. Mapping the signaling network of BIN2 kinase using TurboID-mediated biotin labeling and phosphoproteomics. Kim TW, et al. Plant Cell, 2023 Mar 15. PMID 36660928, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_115222.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables inorganic diphosphate phosphatase activity IDA
    Inferred from Direct Assay
    more info
    		  
    enables inorganic diphosphate phosphatase activity IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    enables magnesium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in phosphate-containing compound metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    pyrophosphorylase 4
    NP_190930.1
    • pyrophosphorylase 4 (PPa4); FUNCTIONS IN: inorganic diphosphatase activity; INVOLVED IN: response to cadmium ion, metabolic process; LOCATED IN: membrane, cytoplasm; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Inorganic pyrophosphatase (InterPro:IPR008162); BEST Arabidopsis thaliana protein match is: pyrophosphorylase 1 (TAIR:AT1G01050.1); Has 5938 Blast hits to 5938 proteins in 1824 species: Archae - 171; Bacteria - 4276; Metazoa - 240; Fungi - 260; Plants - 270; Viruses - 0; Other Eukaryotes - 721 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      19880504..19883743
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_115222.3 → NP_190930.1  pyrophosphorylase 4 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_190930.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8LA73, Q9LFF9
      UniProtKB/TrEMBL
      A0A178VKC0, A0A5S9XLB0
      Conserved Domains (1) summary
      PLN02373
      Location:29 → 216
      PLN02373; soluble inorganic pyrophosphatase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9LFF9.1

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