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    APY1 apyrase 1 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 819563, updated on 10-Oct-2019

    Summary

    Gene symbol
    APY1
    Gene description
    apyrase 1
    Primary source
    Araport:AT3G04080
    Locus tag
    AT3G04080
    Gene type
    protein coding
    RNA name
    apyrase 1
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliophyta; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    apyrase 1; APYRASE 1; ATAPY1; T6K12.30; T6K12_30
    Summary
    Encodes an Golgi-localized integral membrane enzyme with nucleoside diphosphate activity that when mutated in combination with ATAPY2 causes a complete inhibition of pollen germination.

    Genomic context

    See APY1 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    9
    Sequence:
    Chromosome: 3; NC_003074.8 (1067558..1071438, complement)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene NAC domain containing protein 46 Neighboring gene NAC domain containing protein 47 Neighboring gene small and basic intrinsic protein 1A Neighboring gene AGAMOUS-like 57

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    General gene information

    Homology

    • Homologs of the APY1 gene: The APY1 gene is conserved in human, chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, fruit fly, mosquito, C.elegans, S.cerevisiae, K.lactis, S.pombe, M.oryzae, N.crassa, rice, and frog.
    • Orthologs
    NM_111279.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    8-oxo-dGTP phosphohydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    ATPase activity IDA
    Inferred from Direct Assay
    more info
     
    GTP phosphohydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    calmodulin binding IDA
    Inferred from Direct Assay
    more info
     
    dATP phosphohydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    dCTP phosphohydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    dGTP phosphohydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    dTTP phosphohydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    dUTP phosphohydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    guanosine-diphosphatase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nucleoside-diphosphatase activity IDA
    Inferred from Direct Assay
    more info
     
    nucleoside-diphosphatase activity IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    uridine-diphosphatase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Process Evidence Code Pubs
    pollen germination IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    NOT purinergic receptor signaling pathway IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Component Evidence Code Pubs
    Golgi apparatus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Golgi medial cisterna HDA PubMed 
    Golgi membrane IEA
    Inferred from Electronic Annotation
    more info
     
    cytoplasm ISM
    Inferred from Sequence Model
    more info
     
    endosome IDA
    Inferred from Direct Assay
    more info
    PubMed 
    NOT extracellular space IDA
    Inferred from Direct Assay
    more info
    PubMed 
    integral component of membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    NOT plasma membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    trans-Golgi network IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    apyrase 1
    NP_187058.1
    • apyrase 1 (APY1); CONTAINS InterPro DOMAIN/s: Nucleoside phosphatase GDA1/CD39 (InterPro:IPR000407); BEST Arabidopsis thaliana protein match is: apyrase 2 (TAIR:AT5G18280.1); Has 1435 Blast hits to 1431 proteins in 229 species: Archae - 0; Bacteria - 35; Metazoa - 605; Fungi - 313; Plants - 348; Viruses - 0; Other Eukaryotes - 134 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      1067558..1071438 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_111279.5NP_187058.1  apyrase 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_187058.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9SQG2
      Conserved Domains (1) summary
      cl17037
      Location:70470
      NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily
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