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    Agpat4 1-acylglycerol-3-phosphate O-acyltransferase 4 (lysophosphatidic acid acyltransferase, delta) [ Mus musculus (house mouse) ]

    Gene ID: 68262, updated on 5-Jul-2019

    Summary

    Official Symbol
    Agpat4provided by MGI
    Official Full Name
    1-acylglycerol-3-phosphate O-acyltransferase 4 (lysophosphatidic acid acyltransferase, delta)provided by MGI
    Primary source
    MGI:MGI:1915512
    See related
    Ensembl:ENSMUSG00000023827
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    1500003P24Rik
    Expression
    Ubiquitous expression in colon adult (RPKM 23.0), lung adult (RPKM 13.9) and 27 other tissues See more
    Orthologs

    Genomic context

    See Agpat4 in Genome Data Viewer
    Location:
    17; 17 A1
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 17 NC_000083.6 (12118709..12219649)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 17 NC_000083.5 (12312150..12412506)

    Chromosome 17 - NC_000083.6Genomic Context describing neighboring genes Neighboring gene parkin RBR E3 ubiquitin protein ligase Neighboring gene DNA segment, Chr 17, ERATO Doi 648, expressed Neighboring gene predicted gene, 46604 Neighboring gene teratocarcinoma-derived growth factor, pseudogene 2 Neighboring gene RIKEN cDNA 4732491K20 gene Neighboring gene mitogen-activated protein kinase kinase kinase 4 Neighboring gene predicted gene, 46605

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    1-acylglycerol-3-phosphate O-acyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    1-acylglycerol-3-phosphate O-acyltransferase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    lysophosphatidic acid acyltransferase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    transferase activity, transferring acyl groups IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Process Evidence Code Pubs
    lipid metabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    phospholipid biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
     
    phospholipid metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    phospholipid metabolic process IDA
    Inferred from Direct Assay
    more info
    PubMed 
    phospholipid metabolic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    endoplasmic reticulum IDA
    Inferred from Direct Assay
    more info
    PubMed 
    integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    membrane IEA
    Inferred from Electronic Annotation
    more info
     
    mitochondrial outer membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    mitochondrial outer membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    1-acyl-sn-glycerol-3-phosphate acyltransferase delta
    Names
    1-AGP acyltransferase 4
    1-AGPAT 4
    1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, delta)
    LPAAT-delta
    lysophosphatidic acid acyltransferase-delta
    NP_080920.2
    XP_006523408.2
    XP_006523410.1
    XP_006523411.1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_026644.2NP_080920.2  1-acyl-sn-glycerol-3-phosphate acyltransferase delta

      See identical proteins and their annotated locations for NP_080920.2

      Status: PROVISIONAL

      Source sequence(s)
      AK005139
      Consensus CDS
      CCDS28389.1
      UniProtKB/Swiss-Prot
      Q8K4X7
      Related
      ENSMUSP00000024594.2, ENSMUST00000024594.8
      Conserved Domains (1) summary
      PLN02380
      Location:20326
      PLN02380; 1-acyl-sn-glycerol-3-phosphate acyltransferase

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000083.6 Reference GRCm38.p4 C57BL/6J

      Range
      12118709..12219649
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006523345.2XP_006523408.2  1-acyl-sn-glycerol-3-phosphate acyltransferase delta isoform X1

      See identical proteins and their annotated locations for XP_006523408.2

      UniProtKB/Swiss-Prot
      Q8K4X7
      Conserved Domains (1) summary
      PLN02380
      Location:20326
      PLN02380; 1-acyl-sn-glycerol-3-phosphate acyltransferase
    2. XM_006523347.2XP_006523410.1  1-acyl-sn-glycerol-3-phosphate acyltransferase delta isoform X2

      See identical proteins and their annotated locations for XP_006523410.1

      Conserved Domains (2) summary
      cd07990
      Location:11150
      LPLAT_LCLAT1-like; Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LCLAT1-like
      pfam16076
      Location:137208
      Acyltransf_C; Acyltransferase C-terminus
    3. XM_006523348.3XP_006523411.1  1-acyl-sn-glycerol-3-phosphate acyltransferase delta isoform X2

      See identical proteins and their annotated locations for XP_006523411.1

      Conserved Domains (2) summary
      cd07990
      Location:11150
      LPLAT_LCLAT1-like; Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LCLAT1-like
      pfam16076
      Location:137208
      Acyltransf_C; Acyltransferase C-terminus
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