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    Stmn4 stathmin-like 4 [ Mus musculus (house mouse) ]

    Gene ID: 56471, updated on 14-Aug-2019

    Summary

    Official Symbol
    Stmn4provided by MGI
    Official Full Name
    stathmin-like 4provided by MGI
    Primary source
    MGI:MGI:1931224
    See related
    Ensembl:ENSMUSG00000022044
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    RB3; Lagl; R75359
    Expression
    Biased expression in CNS E18 (RPKM 183.1), CNS E14 (RPKM 102.9) and 5 other tissues See more
    Orthologs

    Genomic context

    See Stmn4 in Genome Data Viewer
    Location:
    14; 14 D1
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    108 current GRCm38.p6 (GCF_000001635.26) 14 NC_000080.6 (66344210..66361680)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 14 NC_000080.5 (66963212..66980517)

    Chromosome 14 - NC_000080.6Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 1700001G11 gene Neighboring gene tripartite motif-containing 35 Neighboring gene predicted gene, 41183 Neighboring gene small nucleolar RNA SNORA48 Neighboring gene predicted gene, 41184

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (2) 

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    tubulin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Process Evidence Code Pubs
    microtubule depolymerization IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    neuron projection development IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    regulation of cytoskeleton organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    regulation of microtubule polymerization or depolymerization IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    Golgi apparatus IEA
    Inferred from Electronic Annotation
    more info
     
    cell projection IEA
    Inferred from Electronic Annotation
    more info
     
    cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    neuron projection IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    stathmin-4
    Names
    stathmin-like protein B3
    stathmin-like protein RB3

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001310522.1NP_001297451.1  stathmin-4 isoform 1

      See identical proteins and their annotated locations for NP_001297451.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
      Source sequence(s)
      BC046752, BQ178328, CD776693, CJ062344, CO427355
      Consensus CDS
      CCDS79339.1
      UniProtKB/Swiss-Prot
      P63042
      UniProtKB/TrEMBL
      G3X9Z6
      Related
      ENSMUSP00000113759.1, ENSMUST00000120229.7
      Conserved Domains (1) summary
      pfam00836
      Location:76211
      Stathmin; Stathmin family
    2. NM_001310523.1NP_001297452.1  stathmin-4 isoform 3

      See identical proteins and their annotated locations for NP_001297452.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) lacks an alternate in-frame exon in the 5' coding region and includes an alternate penultimate exon, compared to variant 1, resulting in a novel 3' coding region and longer 3' UTR. It encodes isoform 3 which is shorter and has a distinct C-terminus, compared to isoform 1.
      Source sequence(s)
      BC046752, BE859440, CD776693, CJ062344
      Consensus CDS
      CCDS79340.1
      UniProtKB/Swiss-Prot
      P63042
      UniProtKB/TrEMBL
      Q05DI3
      Related
      ENSMUSP00000113629.1, ENSMUST00000118426.7
      Conserved Domains (1) summary
      pfam00836
      Location:49171
      Stathmin; Stathmin family
    3. NM_019675.3NP_062649.1  stathmin-4 isoform 2

      See identical proteins and their annotated locations for NP_062649.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks an alternate in-frame exon in the 5' coding region compared to variant 1. It encodes isoform 2 which is shorter than isoform 1.
      Source sequence(s)
      BC046752, CJ062344
      Consensus CDS
      CCDS27222.1
      UniProtKB/Swiss-Prot
      P63042
      Related
      ENSMUSP00000074113.6, ENSMUST00000074523.12
      Conserved Domains (1) summary
      pfam00836
      Location:49184
      Stathmin; Stathmin family

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 108 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p6 C57BL/6J

    Genomic

    1. NC_000080.6 Reference GRCm38.p6 C57BL/6J

      Range
      66344210..66361680
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017316097.2XP_017171586.1  stathmin-4 isoform X2

      UniProtKB/TrEMBL
      Q05DI3
      Conserved Domains (1) summary
      pfam00836
      Location:49171
      Stathmin; Stathmin family
    2. XM_006519317.3XP_006519380.1  stathmin-4 isoform X1

      See identical proteins and their annotated locations for XP_006519380.1

      UniProtKB/TrEMBL
      D3Z4C2
      Conserved Domains (1) summary
      pfam00836
      Location:76198
      Stathmin; Stathmin family
    3. XM_006519316.3XP_006519379.1  stathmin-4 isoform X1

      See identical proteins and their annotated locations for XP_006519379.1

      UniProtKB/TrEMBL
      D3Z4C2
      Related
      ENSMUSP00000113788.1, ENSMUST00000121955.7
      Conserved Domains (1) summary
      pfam00836
      Location:76198
      Stathmin; Stathmin family
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