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    TRERF1 transcriptional regulating factor 1 [ Homo sapiens (human) ]

    Gene ID: 55809, updated on 13-Feb-2019

    Summary

    Official Symbol
    TRERF1provided by HGNC
    Official Full Name
    transcriptional regulating factor 1provided by HGNC
    Primary source
    HGNC:HGNC:18273
    See related
    Ensembl:ENSG00000124496 MIM:610322
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    RAPA; BCAR2; TREP132; TReP-132; HSA277276; dJ139D8.5
    Summary
    This gene encodes a zinc-finger transcriptional regulating protein which interacts with CBP/p300 to regulate the human gene CYP11A1. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2014]
    Expression
    Ubiquitous expression in testis (RPKM 2.9), bone marrow (RPKM 2.6) and 24 other tissues See more
    Orthologs

    Genomic context

    See TRERF1 in Genome Data Viewer
    Location:
    6p21.1
    Exon count:
    26
    Annotation release Status Assembly Chr Location
    109 current GRCh38.p12 (GCF_000001405.38) 6 NC_000006.12 (42224933..42452216, complement)
    105 previous assembly GRCh37.p13 (GCF_000001405.25) 6 NC_000006.11 (42192669..42419943, complement)

    Chromosome 6 - NC_000006.12Genomic Context describing neighboring genes Neighboring gene guanylate cyclase activator 1B Neighboring gene mitochondrial ribosomal protein S10 Neighboring gene uncharacterized LOC105375061 Neighboring gene arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2-like Neighboring gene ribosomal protein L36a pseudogene 5

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Pathways from BioSystems

    • Endoderm Differentiation, organism-specific biosystem (from WikiPathways)
      Endoderm Differentiation, organism-specific biosystemModel depicting endoderm specification based on the literature and highly enriched gene expression profiles via comparison across dozens of independent induced and embryonic pluripotent stem cell lin...
    • Mesodermal Commitment Pathway, organism-specific biosystem (from WikiPathways)
      Mesodermal Commitment Pathway, organism-specific biosystemModel depicting mesodermal specification based on the literature and highly enriched gene expression profiles via comparison across dozens of independent induced and embryonic pluripotent stem cell l...

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • FLJ21198

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    DNA binding, bending NAS
    Non-traceable Author Statement
    more info
    PubMed 
    DNA-binding transcription factor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    DNA-binding transcription factor activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    DNA-binding transcription factor activity, RNA polymerase II-specific ISA
    Inferred from Sequence Alignment
    more info
     
    DNA-binding transcription factor activity, RNA polymerase II-specific ISM
    Inferred from Sequence Model
    more info
    PubMed 
    DNA-binding transcription factor activity, RNA polymerase II-specific NAS
    Non-traceable Author Statement
    more info
    PubMed 
    metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    nuclear receptor transcription coactivator activity NAS
    Non-traceable Author Statement
    more info
    PubMed 
    transcription coregulator activity NAS
    Non-traceable Author Statement
    more info
    PubMed 
    transcription factor binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    transcription factor binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    transcription regulatory region DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Process Evidence Code Pubs
    cholesterol catabolic process NAS
    Non-traceable Author Statement
    more info
    PubMed 
    homeostatic process NAS
    Non-traceable Author Statement
    more info
    PubMed 
    multicellular organism development NAS
    Non-traceable Author Statement
    more info
    PubMed 
    positive regulation of transcription, DNA-templated IDA
    Inferred from Direct Assay
    more info
    PubMed 
    regulation of hormone biosynthetic process NAS
    Non-traceable Author Statement
    more info
    PubMed 
    regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
     
    steroid biosynthetic process NAS
    Non-traceable Author Statement
    more info
    PubMed 
    Component Evidence Code Pubs
    cytosol IDA
    Inferred from Direct Assay
    more info
     
    histone deacetylase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    nucleolus IDA
    Inferred from Direct Assay
    more info
     
    nucleoplasm IDA
    Inferred from Direct Assay
    more info
     
    nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    transcription factor complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    transcriptional-regulating factor 1
    Names
    breast cancer anti-estrogen resistance 2
    rapa-1
    rapa-2
    transcriptional regulating protein 132
    zinc finger protein rapa
    zinc finger transcription factor TReP-132

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001297573.1NP_001284502.1  transcriptional-regulating factor 1 isoform 1

      See identical proteins and their annotated locations for NP_001284502.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (1) represents the longer transript and encodes the longer isoform (1).
      Source sequence(s)
      AF297872, AL096814, AM404182
      Consensus CDS
      CCDS75455.1
      UniProtKB/Swiss-Prot
      Q96PN7
      UniProtKB/TrEMBL
      Q05GC8
      Related
      ENSP00000439689.1, ENST00000541110.5
      Conserved Domains (5) summary
      smart00717
      Location:908953
      SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
      sd00017
      Location:10351057
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01448
      Location:801855
      ELM2; ELM2 domain
      pfam13912
      Location:514534
      zf-C2H2_6; C2H2-type zinc finger
      cl21498
      Location:909953
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
    2. NM_033502.3NP_277037.1  transcriptional-regulating factor 1 isoform 2

      See identical proteins and their annotated locations for NP_277037.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (2) uses an alternate in-frame splice donor site in the 5' coding region, compared to variant 1. Variant 2 encodes a shorter isoform (2), compared to isoform 1.
      Source sequence(s)
      AF297872, AL096814, AM404182, AM404183
      Consensus CDS
      CCDS4867.1
      UniProtKB/Swiss-Prot
      Q96PN7
      UniProtKB/TrEMBL
      Q05GC8
      Related
      ENSP00000362013.4, ENST00000372922.8
      Conserved Domains (5) summary
      smart00717
      Location:888933
      SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
      sd00017
      Location:10151037
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01448
      Location:781835
      ELM2; ELM2 domain
      pfam13912
      Location:514534
      zf-C2H2_6; C2H2-type zinc finger
      cl21498
      Location:889933
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...

    RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p12 Primary Assembly

    Genomic

    1. NC_000006.12 Reference GRCh38.p12 Primary Assembly

      Range
      42224933..42452216 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017011055.1XP_016866544.1  transcriptional-regulating factor 1 isoform X12

    2. XM_017011037.1XP_016866526.1  transcriptional-regulating factor 1 isoform X1

      Conserved Domains (4) summary
      smart00717
      Location:950995
      SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
      pfam01448
      Location:801855
      ELM2; ELM2 domain
      pfam13912
      Location:514534
      zf-C2H2_6; C2H2-type zinc finger
      cl21498
      Location:951995
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
    3. XM_017011050.1XP_016866539.1  transcriptional-regulating factor 1 isoform X8

      Conserved Domains (4) summary
      smart00717
      Location:950995
      SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
      pfam01448
      Location:801855
      ELM2; ELM2 domain
      pfam13912
      Location:514534
      zf-C2H2_6; C2H2-type zinc finger
      cl21498
      Location:951995
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
    4. XM_011514741.2XP_011513043.1  transcriptional-regulating factor 1 isoform X1

      See identical proteins and their annotated locations for XP_011513043.1

      Conserved Domains (4) summary
      smart00717
      Location:950995
      SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
      pfam01448
      Location:801855
      ELM2; ELM2 domain
      pfam13912
      Location:514534
      zf-C2H2_6; C2H2-type zinc finger
      cl21498
      Location:951995
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
    5. XM_017011034.1XP_016866523.1  transcriptional-regulating factor 1 isoform X1

      Conserved Domains (4) summary
      smart00717
      Location:950995
      SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
      pfam01448
      Location:801855
      ELM2; ELM2 domain
      pfam13912
      Location:514534
      zf-C2H2_6; C2H2-type zinc finger
      cl21498
      Location:951995
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
    6. XM_011514743.2XP_011513045.1  transcriptional-regulating factor 1 isoform X1

      See identical proteins and their annotated locations for XP_011513045.1

      Conserved Domains (4) summary
      smart00717
      Location:950995
      SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
      pfam01448
      Location:801855
      ELM2; ELM2 domain
      pfam13912
      Location:514534
      zf-C2H2_6; C2H2-type zinc finger
      cl21498
      Location:951995
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
    7. XM_011514742.2XP_011513044.1  transcriptional-regulating factor 1 isoform X1

      See identical proteins and their annotated locations for XP_011513044.1

      Conserved Domains (4) summary
      smart00717
      Location:950995
      SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
      pfam01448
      Location:801855
      ELM2; ELM2 domain
      pfam13912
      Location:514534
      zf-C2H2_6; C2H2-type zinc finger
      cl21498
      Location:951995
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
    8. XM_017011038.1XP_016866527.1  transcriptional-regulating factor 1 isoform X1

      Conserved Domains (4) summary
      smart00717
      Location:950995
      SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
      pfam01448
      Location:801855
      ELM2; ELM2 domain
      pfam13912
      Location:514534
      zf-C2H2_6; C2H2-type zinc finger
      cl21498
      Location:951995
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
    9. XM_017011047.1XP_016866536.1  transcriptional-regulating factor 1 isoform X5

      Conserved Domains (4) summary
      smart00717
      Location:904949
      SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
      pfam01448
      Location:755809
      ELM2; ELM2 domain
      pfam13912
      Location:514534
      zf-C2H2_6; C2H2-type zinc finger
      cl21498
      Location:905949
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
    10. XM_017011045.1XP_016866534.1  transcriptional-regulating factor 1 isoform X3

      Conserved Domains (4) summary
      smart00717
      Location:930975
      SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
      pfam01448
      Location:781835
      ELM2; ELM2 domain
      pfam13912
      Location:514534
      zf-C2H2_6; C2H2-type zinc finger
      cl21498
      Location:931975
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
    11. XM_017011044.1XP_016866533.1  transcriptional-regulating factor 1 isoform X2

      Conserved Domains (5) summary
      smart00717
      Location:950995
      SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
      sd00017
      Location:10771099
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01448
      Location:801855
      ELM2; ELM2 domain
      pfam13912
      Location:514534
      zf-C2H2_6; C2H2-type zinc finger
      cl21498
      Location:951995
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
    12. XM_011514744.1XP_011513046.1  transcriptional-regulating factor 1 isoform X1

      See identical proteins and their annotated locations for XP_011513046.1

      Conserved Domains (4) summary
      smart00717
      Location:950995
      SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
      pfam01448
      Location:801855
      ELM2; ELM2 domain
      pfam13912
      Location:514534
      zf-C2H2_6; C2H2-type zinc finger
      cl21498
      Location:951995
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
    13. XM_017011054.1XP_016866543.1  transcriptional-regulating factor 1 isoform X11

      UniProtKB/Swiss-Prot
      Q96PN7
      Related
      ENSP00000346285.2, ENST00000354325.2
      Conserved Domains (5) summary
      smart00717
      Location:805850
      SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
      sd00017
      Location:932954
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01448
      Location:698752
      ELM2; ELM2 domain
      pfam13912
      Location:514534
      zf-C2H2_6; C2H2-type zinc finger
      cl21498
      Location:806850
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
    14. XM_017011052.1XP_016866541.1  transcriptional-regulating factor 1 isoform X10

      UniProtKB/Swiss-Prot
      Q96PN7
      Related
      ENSP00000339438.2, ENST00000340840.6
      Conserved Domains (4) summary
      smart00717
      Location:805850
      SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
      pfam01448
      Location:698752
      ELM2; ELM2 domain
      pfam13912
      Location:514534
      zf-C2H2_6; C2H2-type zinc finger
      cl21498
      Location:806850
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
    15. XM_017011051.1XP_016866540.1  transcriptional-regulating factor 1 isoform X9

      Conserved Domains (4) summary
      smart00717
      Location:847892
      SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
      pfam01448
      Location:698752
      ELM2; ELM2 domain
      pfam13912
      Location:514534
      zf-C2H2_6; C2H2-type zinc finger
      cl21498
      Location:848892
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
    16. XM_017011049.1XP_016866538.1  transcriptional-regulating factor 1 isoform X7

      UniProtKB/Swiss-Prot
      Q96PN7
      Conserved Domains (5) summary
      smart00717
      Location:888933
      SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
      sd00017
      Location:10151037
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01448
      Location:781835
      ELM2; ELM2 domain
      pfam13912
      Location:514534
      zf-C2H2_6; C2H2-type zinc finger
      cl21498
      Location:889933
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
    17. XM_017011048.1XP_016866537.1  transcriptional-regulating factor 1 isoform X6

      UniProtKB/TrEMBL
      Q05GC8
      Conserved Domains (5) summary
      smart00717
      Location:908953
      SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
      sd00017
      Location:10351057
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01448
      Location:801855
      ELM2; ELM2 domain
      pfam13912
      Location:514534
      zf-C2H2_6; C2H2-type zinc finger
      cl21498
      Location:909953
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
    18. XM_017011046.1XP_016866535.1  transcriptional-regulating factor 1 isoform X4

      Conserved Domains (4) summary
      smart00717
      Location:908953
      SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
      pfam01448
      Location:801855
      ELM2; ELM2 domain
      pfam13912
      Location:514534
      zf-C2H2_6; C2H2-type zinc finger
      cl21498
      Location:909953
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
    19. XM_017011053.1XP_016866542.1  transcriptional-regulating factor 1 isoform X10

      UniProtKB/Swiss-Prot
      Q96PN7
      Conserved Domains (4) summary
      smart00717
      Location:805850
      SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
      pfam01448
      Location:698752
      ELM2; ELM2 domain
      pfam13912
      Location:514534
      zf-C2H2_6; C2H2-type zinc finger
      cl21498
      Location:806850
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
    20. XM_017011040.1XP_016866529.1  transcriptional-regulating factor 1 isoform X1

      Conserved Domains (4) summary
      smart00717
      Location:950995
      SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
      pfam01448
      Location:801855
      ELM2; ELM2 domain
      pfam13912
      Location:514534
      zf-C2H2_6; C2H2-type zinc finger
      cl21498
      Location:951995
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
    21. XM_017011041.1XP_016866530.1  transcriptional-regulating factor 1 isoform X1

      Conserved Domains (4) summary
      smart00717
      Location:950995
      SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
      pfam01448
      Location:801855
      ELM2; ELM2 domain
      pfam13912
      Location:514534
      zf-C2H2_6; C2H2-type zinc finger
      cl21498
      Location:951995
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
    22. XM_011514745.1XP_011513047.1  transcriptional-regulating factor 1 isoform X1

      See identical proteins and their annotated locations for XP_011513047.1

      Conserved Domains (4) summary
      smart00717
      Location:950995
      SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
      pfam01448
      Location:801855
      ELM2; ELM2 domain
      pfam13912
      Location:514534
      zf-C2H2_6; C2H2-type zinc finger
      cl21498
      Location:951995
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
    23. XM_017011039.1XP_016866528.1  transcriptional-regulating factor 1 isoform X1

      Conserved Domains (4) summary
      smart00717
      Location:950995
      SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
      pfam01448
      Location:801855
      ELM2; ELM2 domain
      pfam13912
      Location:514534
      zf-C2H2_6; C2H2-type zinc finger
      cl21498
      Location:951995
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
    24. XM_017011035.1XP_016866524.1  transcriptional-regulating factor 1 isoform X1

      Conserved Domains (4) summary
      smart00717
      Location:950995
      SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
      pfam01448
      Location:801855
      ELM2; ELM2 domain
      pfam13912
      Location:514534
      zf-C2H2_6; C2H2-type zinc finger
      cl21498
      Location:951995
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
    25. XM_017011036.1XP_016866525.1  transcriptional-regulating factor 1 isoform X1

      Conserved Domains (4) summary
      smart00717
      Location:950995
      SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
      pfam01448
      Location:801855
      ELM2; ELM2 domain
      pfam13912
      Location:514534
      zf-C2H2_6; C2H2-type zinc finger
      cl21498
      Location:951995
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
    26. XM_017011042.1XP_016866531.1  transcriptional-regulating factor 1 isoform X1

      Conserved Domains (4) summary
      smart00717
      Location:950995
      SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
      pfam01448
      Location:801855
      ELM2; ELM2 domain
      pfam13912
      Location:514534
      zf-C2H2_6; C2H2-type zinc finger
      cl21498
      Location:951995
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
    27. XM_017011043.1XP_016866532.1  transcriptional-regulating factor 1 isoform X1

      Conserved Domains (4) summary
      smart00717
      Location:950995
      SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
      pfam01448
      Location:801855
      ELM2; ELM2 domain
      pfam13912
      Location:514534
      zf-C2H2_6; C2H2-type zinc finger
      cl21498
      Location:951995
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_018415.1: Suppressed sequence

      Description
      NM_018415.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.
    2. NM_033501.1: Suppressed sequence

      Description
      NM_033501.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.
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