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    Lhpp phospholysine phosphohistidine inorganic pyrophosphate phosphatase [ Rattus norvegicus (Norway rat) ]

    Gene ID: 361663, updated on 18-Apr-2019

    Summary

    Official Symbol
    Lhppprovided by RGD
    Official Full Name
    phospholysine phosphohistidine inorganic pyrophosphate phosphataseprovided by RGD
    Primary source
    RGD:1359187
    See related
    Ensembl:ENSRNOG00000017097
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Expression
    Biased expression in Kidney (RPKM 80.3), Liver (RPKM 61.9) and 9 other tissues See more
    Orthologs

    Genomic context

    See Lhpp in Genome Data Viewer
    Location:
    1q41
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    106 current Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (204617804..204708987)
    104 previous assembly Rnor_5.0 (GCF_000001895.4) 1 NC_005100.3 (211611470..211702233)

    Chromosome 1 - NC_005100.4Genomic Context describing neighboring genes Neighboring gene ornithine aminotransferase Neighboring gene NK1 homeobox 2 Neighboring gene family with sequence similarity 53, member B Neighboring gene uncharacterized LOC102552031 Neighboring gene EEF1A lysine methyltransferase 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Pathways from BioSystems

    General gene information

    Markers

    Homology

    Clone Names

    • MGC95092

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    inorganic diphosphatase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    inorganic diphosphatase activity ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    inorganic diphosphatase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    magnesium ion binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    phosphatase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    protein histidine phosphatase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    protein histidine phosphatase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    protein homodimerization activity IEA
    Inferred from Electronic Annotation
    more info
     
    protein homodimerization activity ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    Process Evidence Code Pubs
    dephosphorylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    phosphate-containing compound metabolic process ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    phosphate-containing compound metabolic process ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    protein dephosphorylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    protein dephosphorylation ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    cytosol ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    cytosol ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    nuclear speck IEA
    Inferred from Electronic Annotation
    more info
     
    nuclear speck ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    General protein information

    Preferred Names
    phospholysine phosphohistidine inorganic pyrophosphate phosphatase
    NP_001009706.1
    XP_008758133.1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001009706.1NP_001009706.1  phospholysine phosphohistidine inorganic pyrophosphate phosphatase

      See identical proteins and their annotated locations for NP_001009706.1

      Status: PROVISIONAL

      Source sequence(s)
      BC088448
      UniProtKB/Swiss-Prot
      Q5I0D5
      Related
      ENSRNOP00000022971.3, ENSRNOT00000022971.3
      Conserved Domains (3) summary
      TIGR01458
      Location:11267
      HAD-SF-IIA-hyp3; HAD-superfamily subfamily IIA hydrolase, TIGR01458
      pfam13242
      Location:186260
      Hydrolase_like; HAD-hyrolase-like
      pfam13344
      Location:14112
      Hydrolase_6; Haloacid dehalogenase-like hydrolase

    RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Rnor_6.0 Primary Assembly

    Genomic

    1. NC_005100.4 Reference Rnor_6.0 Primary Assembly

      Range
      204617804..204708987
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_008759911.2XP_008758133.1  phospholysine phosphohistidine inorganic pyrophosphate phosphatase isoform X1

      Conserved Domains (3) summary
      TIGR01458
      Location:11249
      HAD-SF-IIA-hyp3; HAD-superfamily subfamily IIA hydrolase, TIGR01458
      pfam13242
      Location:186244
      Hydrolase_like; HAD-hyrolase-like
      pfam13344
      Location:14112
      Hydrolase_6; Haloacid dehalogenase-like hydrolase

    Alternate Rn_Celera

    Genomic

    1. AC_000069.1 Alternate Rn_Celera

      Range
      185148002..185239039
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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