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    FTMT ferritin mitochondrial [ Homo sapiens (human) ]

    Gene ID: 94033, updated on 29-Mar-2018
    Official Symbol
    FTMTprovided by HGNC
    Official Full Name
    ferritin mitochondrialprovided by HGNC
    Primary source
    HGNC:HGNC:17345
    See related
    Ensembl:ENSG00000181867 MIM:608847; Vega:OTTHUMG00000128912
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    MTF
    Orthologs
    Location:
    5q23.1
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    109 current GRCh38.p12 (GCF_000001405.38) 5 NC_000005.10 (121851955..121852833)
    105 previous assembly GRCh37.p13 (GCF_000001405.25) 5 NC_000005.9 (121187650..121188528)

    Chromosome 5 - NC_000005.10Genomic Context describing neighboring genes Neighboring gene ribosomal L24 domain containing 1 pseudogene 10 Neighboring gene uncharacterized LOC105379150 Neighboring gene uncharacterized LOC105379149 Neighboring gene uncharacterized LOC105379148 Neighboring gene serum response factor binding protein 1 Neighboring gene lysyl oxidase

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    NHGRI GWAS Catalog

    Description
    A genome-wide association study (GWAS) for bronchopulmonary dysplasia.
    NHGRI GWA Catalog
    Genetic variation modifies risk for neurodegeneration based on biomarker status.
    NHGRI GWA Catalog
    Genome-wide association studies and heritability estimates of body mass index related phenotypes in bangladeshi adults.
    NHGRI GWA Catalog
    • Ferroptosis, organism-specific biosystem (from KEGG)
      Ferroptosis, organism-specific biosystemFerroptosis is a regulated form of cell death and characterized by a production of reactive oxygen species (ROS) from accumulated iron and lipid peroxidation. It can be induced by experimental compou...
    • Ferroptosis, conserved biosystem (from KEGG)
      Ferroptosis, conserved biosystemFerroptosis is a regulated form of cell death and characterized by a production of reactive oxygen species (ROS) from accumulated iron and lipid peroxidation. It can be induced by experimental compou...

    Markers

    Homology

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    ferric iron binding IEA
    Inferred from Electronic Annotation
    more info
     
    ferroxidase activity TAS
    Traceable Author Statement
    more info
     
    iron ion binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    cellular iron ion homeostasis IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cellular iron ion homeostasis TAS
    Traceable Author Statement
    more info
     
    intracellular sequestering of iron ion IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    iron ion transport IEA
    Inferred from Electronic Annotation
    more info
     
    oxidation-reduction process IEA
    Inferred from Electronic Annotation
    more info
     
    positive regulation of aconitate hydratase activity IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    positive regulation of cell proliferation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    positive regulation of lyase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    positive regulation of succinate dehydrogenase activity IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    Component Evidence Code Pubs
    cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    mitochondrial matrix TAS
    Traceable Author Statement
    more info
     
    mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    nucleus HDA PubMed 
    Preferred Names
    ferritin, mitochondrial
    Names
    ferritin H subunit
    mitochondrial ferritin
    NP_803431.1

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_177478.1NP_803431.1  ferritin, mitochondrial precursor

      See identical proteins and their annotated locations for NP_803431.1

      Status: VALIDATED

      Source sequence(s)
      BC034419
      Consensus CDS
      CCDS4128.1
      UniProtKB/Swiss-Prot
      Q8N4E7
      Related
      ENSP00000313691.1, OTTHUMP00000159158, ENST00000321339.2, OTTHUMT00000250884
      Conserved Domains (2) summary
      cd01056
      Location:73233
      Euk_Ferritin; eukaryotic ferritins
      pfam00210
      Location:77218
      Ferritin; Ferritin-like domain

    RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p12 Primary Assembly

    Genomic

    1. NC_000005.10 Reference GRCh38.p12 Primary Assembly

      Range
      121851955..121852833
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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