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    FAM110B family with sequence similarity 110 member B [ Homo sapiens (human) ]

    Gene ID: 90362, updated on 8-Apr-2018
    Official Symbol
    FAM110Bprovided by HGNC
    Official Full Name
    family with sequence similarity 110 member Bprovided by HGNC
    Primary source
    HGNC:HGNC:28587
    See related
    Ensembl:ENSG00000169122 MIM:611394; Vega:OTTHUMG00000164282
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    C8orf72
    Expression
    Broad expression in spleen (RPKM 2.9), brain (RPKM 1.5) and 19 other tissues See more
    Orthologs
    Location:
    8q12.1
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    109 current GRCh38.p12 (GCF_000001405.38) 8 NC_000008.11 (57994509..58149718)
    105 previous assembly GRCh37.p13 (GCF_000001405.25) 8 NC_000008.10 (58907068..59062277)

    Chromosome 8 - NC_000008.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105375856 Neighboring gene long intergenic non-protein coding RNA 1602 Neighboring gene ribosomal protein L26 pseudogene 26 Neighboring gene uncharacterized LOC107986945 Neighboring gene VISTA enhancer hs1364 Neighboring gene uncharacterized LOC101929528

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Jun 15 11:32:44 2016

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    NHGRI GWAS Catalog

    Description
    A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder.
    NHGRI GWA Catalog
    Genome-wide association study identifies 8 novel loci associated with blood pressure responses to interventions in Han Chinese.
    NHGRI GWA Catalog
    Genome-Wide Association Study of Primary Dentition Pit-and-Fissure and Smooth Surface Caries.
    NHGRI GWA Catalog
    Products Interactant Other Gene Complex Source Pubs Description

    Markers

    Homology

    Clone Names

    • MGC39325

    Gene Ontology Provided by GOA

    Component Evidence Code Pubs
    cytosol IDA
    Inferred from Direct Assay
    more info
     
    microtubule organizing center IEA
    Inferred from Electronic Annotation
    more info
     
    mitochondrion IDA
    Inferred from Direct Assay
    more info
     

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_147189.2NP_671722.1  protein FAM110B

      See identical proteins and their annotated locations for NP_671722.1

      Status: VALIDATED

      Source sequence(s)
      AC110013, AK092221
      Consensus CDS
      CCDS6170.1
      UniProtKB/Swiss-Prot
      Q8TC76
      UniProtKB/TrEMBL
      A0A024R7V5, B3KRT5
      Related
      ENSP00000355204.3, OTTHUMP00000226349, ENST00000361488.7, OTTHUMT00000378095
      Conserved Domains (2) summary
      pfam14160
      Location:253361
      FAM110_C; Centrosome-associated C terminus
      pfam14161
      Location:13118
      FAM110_N; Centrosome-associated N terminus

    RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p12 Primary Assembly

    Genomic

    1. NC_000008.11 Reference GRCh38.p12 Primary Assembly

      Range
      57994509..58149718
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005251324.3XP_005251381.1  protein FAM110B isoform X1

      See identical proteins and their annotated locations for XP_005251381.1

      UniProtKB/Swiss-Prot
      Q8TC76
      UniProtKB/TrEMBL
      A0A024R7V5
      Conserved Domains (2) summary
      pfam14160
      Location:253361
      FAM110_C; Centrosome-associated C terminus
      pfam14161
      Location:13118
      FAM110_N; Centrosome-associated N terminus
    2. XM_017013948.1XP_016869437.1  protein FAM110B isoform X1

      UniProtKB/Swiss-Prot
      Q8TC76
      UniProtKB/TrEMBL
      A0A024R7V5
      Conserved Domains (2) summary
      pfam14160
      Location:253361
      FAM110_C; Centrosome-associated C terminus
      pfam14161
      Location:13118
      FAM110_N; Centrosome-associated N terminus
    3. XM_005251325.3XP_005251382.1  protein FAM110B isoform X1

      See identical proteins and their annotated locations for XP_005251382.1

      UniProtKB/Swiss-Prot
      Q8TC76
      UniProtKB/TrEMBL
      A0A024R7V5
      Conserved Domains (2) summary
      pfam14160
      Location:253361
      FAM110_C; Centrosome-associated C terminus
      pfam14161
      Location:13118
      FAM110_N; Centrosome-associated N terminus
    4. XM_005251326.3XP_005251383.1  protein FAM110B isoform X1

      See identical proteins and their annotated locations for XP_005251383.1

      UniProtKB/Swiss-Prot
      Q8TC76
      UniProtKB/TrEMBL
      A0A024R7V5
      Conserved Domains (2) summary
      pfam14160
      Location:253361
      FAM110_C; Centrosome-associated C terminus
      pfam14161
      Location:13118
      FAM110_N; Centrosome-associated N terminus
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