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    Rbm12 RNA binding motif protein 12 [ Mus musculus (house mouse) ]

    Gene ID: 75710, updated on 27-Jan-2018
    Official Symbol
    Rbm12provided by MGI
    Official Full Name
    RNA binding motif protein 12provided by MGI
    Primary source
    MGI:MGI:1922960
    See related
    Ensembl:ENSMUSG00000089824 Vega:OTTMUSG00000016088
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    SWAN; AI852903; mKIAA0765; 5730420G12Rik; 9430070C08Rik
    Summary
    This gene encodes a protein that contains several RNA-binding motifs, potential transmembrane domains, and proline-rich regions. This gene and the gene for copine I overlap at map location 2 H2. Two alternatively spliced transcript variants have been identified for this gene. Both variants encode the same protein. [provided by RefSeq, Jul 2008]
    Expression
    Ubiquitous expression in thymus adult (RPKM 9.7), CNS E11.5 (RPKM 8.4) and 28 other tissues See more
    Orthologs
    Location:
    2; 2 H1
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 2 NC_000068.7 (156094882..156111965, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 2 NC_000068.6 (155920618..155937701, complement)

    Chromosome 2 - NC_000068.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 39970 Neighboring gene sperm associated antigen 4 Neighboring gene copine I Neighboring gene nitrogen fixation gene 1 (S. cerevisiae) Neighboring gene reactive oxygen species modulator 1 Neighboring gene RNA binding motif protein 39

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • mRNA processing, organism-specific biosystem (from WikiPathways)
      mRNA processing, organism-specific biosystemAdapted from Reactome, see: [http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_1675.1 REACT 1675.1] This process describes the conversion of precursor messenger RNA into mature messenge...

    Markers

    Homology

    Clone Names

    • MGC30712, MGC38279

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    RNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    biological_process ND
    No biological Data available
    more info
     
    Component Evidence Code Pubs
    nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    Preferred Names
    RNA-binding protein 12
    Names
    SH3/WW domain anchor protein in the nucleus

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_029397.3NP_083673.3  RNA-binding protein 12

      See identical proteins and their annotated locations for NP_083673.3

      Status: REVIEWED

      Description
      Transcript Variant: This variant (1) is the longer transcript.
      Source sequence(s)
      AL833786
      Consensus CDS
      CCDS16961.1
      UniProtKB/Swiss-Prot
      Q8R4X3
      Related
      ENSMUSP00000050461.5, OTTMUSP00000017204, ENSMUST00000059647.11, OTTMUST00000038405
      Conserved Domains (6) summary
      COG0724
      Location:401610
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      cd12512
      Location:421521
      RRM3_RBM12; RNA recognition motif 3 in RNA-binding protein 12 (RBM12) and similar proteins
      cd12745
      Location:192
      RRM1_RBM12; RNA recognition motif 1 in RNA-binding protein 12 (RBM12) and similar proteins
      cd12747
      Location:303377
      RRM2_RBM12; RNA recognition motif 2 in RNA-binding protein 12 (RBM12) and similar proteins
      cd12749
      Location:545632
      RRM4_RBM12; RNA recognition motif 4 in RNA-binding protein 12 (RBM12) and similar proteins
      cd12751
      Location:915989
      RRM5_RBM12; RNA recognition motif 5 in RNA-binding protein 12 (RBM12) and similar proteins
    2. NM_170598.2NP_733486.2  RNA-binding protein 12

      See identical proteins and their annotated locations for NP_733486.2

      Status: REVIEWED

      Description
      Transcript Variant: This variant (2) uses a different splice site which creates a shorter 5' UTR when compared to variant 1.
      Source sequence(s)
      AL833786
      Consensus CDS
      CCDS16961.1
      UniProtKB/Swiss-Prot
      Q8R4X3
      Related
      ENSMUSP00000105233.1, OTTMUSP00000017221, ENSMUST00000109604.8, OTTMUST00000038463
      Conserved Domains (6) summary
      COG0724
      Location:401610
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      cd12512
      Location:421521
      RRM3_RBM12; RNA recognition motif 3 in RNA-binding protein 12 (RBM12) and similar proteins
      cd12745
      Location:192
      RRM1_RBM12; RNA recognition motif 1 in RNA-binding protein 12 (RBM12) and similar proteins
      cd12747
      Location:303377
      RRM2_RBM12; RNA recognition motif 2 in RNA-binding protein 12 (RBM12) and similar proteins
      cd12749
      Location:545632
      RRM4_RBM12; RNA recognition motif 4 in RNA-binding protein 12 (RBM12) and similar proteins
      cd12751
      Location:915989
      RRM5_RBM12; RNA recognition motif 5 in RNA-binding protein 12 (RBM12) and similar proteins

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000068.7 Reference GRCm38.p4 C57BL/6J

      Range
      156094882..156111965 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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