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    Mro maestro [ Mus musculus (house mouse) ]

    Gene ID: 71263, updated on 10-Mar-2018
    Official Symbol
    Mroprovided by MGI
    Official Full Name
    maestroprovided by MGI
    Primary source
    MGI:MGI:2152817
    See related
    Ensembl:ENSMUSG00000064036 Vega:OTTMUSG00000028221
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    4930507C04Rik; 4933435E20Rik
    Expression
    Biased expression in testis adult (RPKM 3.0), ovary adult (RPKM 2.7) and 11 other tissues See more
    Orthologs
    Location:
    18; 18 E2
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 18 NC_000084.6 (73851821..73881334)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 18 NC_000084.5 (74019041..74038788)

    Chromosome 18 - NC_000084.6Genomic Context describing neighboring genes Neighboring gene malic enzyme 2, NAD(+)-dependent, mitochondrial Neighboring gene predicted gene, 46631 Neighboring gene predicted gene, 32661 Neighboring gene mitogen-activated protein kinase 4 Neighboring gene RIKEN cDNA D730045A05 gene Neighboring gene predicted gene 9925

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    biological_process ND
    No biological Data available
    more info
     
    Component Evidence Code Pubs
    nucleolus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Preferred Names
    protein maestro
    Names
    male-specific transcription in the developing reproductive organs

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001305882.1NP_001292811.1  protein maestro isoform 1

      See identical proteins and their annotated locations for NP_001292811.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) differs in the 5' UTR and has multiple coding region differences, compared to variant 3. These differences cause translation initiation at a downstream AUG and result in an isoform (1) with a shorter N-terminus, compared to isoform 3.
      Source sequence(s)
      AC124367, AK017067, AK140653, BY088818, CK335185
      Consensus CDS
      CCDS79663.1
      UniProtKB/Swiss-Prot
      Q7TNB4
      UniProtKB/TrEMBL
      E9QNX2
      Related
      ENSMUSP00000113434.1, OTTMUSP00000035574, ENSMUST00000120033.7, OTTMUST00000069919
      Conserved Domains (1) summary
      sd00044
      Location:4674
      HEAT; HEAT repeat [structural motif]
    2. NM_001360973.1NP_001347902.1  protein maestro isoform 3

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) encodes the longest isoform (3).
      Source sequence(s)
      AC124367
      Conserved Domains (1) summary
      sd00044
      Location:183211
      HEAT; HEAT repeat [structural motif]
    3. NM_027741.3NP_082017.2  protein maestro isoform 2

      See identical proteins and their annotated locations for NP_082017.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR and has multiple coding region differences, compared to variant 3. These differences cause translation initiation at a downstream AUG and result in an isoform (2) with a shorter N-terminus, compared to isoform 3.
      Source sequence(s)
      AC124367, AK017067, AK140653, BY088818, CK335185
      Consensus CDS
      CCDS50319.1
      UniProtKB/Swiss-Prot
      Q7TNB4
      UniProtKB/TrEMBL
      E9PUF9
      Related
      ENSMUSP00000113392.1, OTTMUSP00000035575, ENSMUST00000119239.7, OTTMUST00000069922
      Conserved Domains (1) summary
      sd00044
      Location:4674
      HEAT; HEAT repeat [structural motif]

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000084.6 Reference GRCm38.p4 C57BL/6J

      Range
      73851821..73881334
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006526255.3XP_006526318.3  protein maestro isoform X7

    2. XM_006526259.3XP_006526322.1  protein maestro isoform X12

      See identical proteins and their annotated locations for XP_006526322.1

      UniProtKB/TrEMBL
      E9QNX2
      Conserved Domains (1) summary
      sd00044
      Location:4674
      HEAT; HEAT repeat [structural motif]
    3. XM_006526257.3XP_006526320.1  protein maestro isoform X12

      See identical proteins and their annotated locations for XP_006526320.1

      UniProtKB/TrEMBL
      E9QNX2
      Related
      ENSMUSP00000136775.1, ENSMUST00000179472.7
      Conserved Domains (1) summary
      sd00044
      Location:4674
      HEAT; HEAT repeat [structural motif]
    4. XM_011247006.2XP_011245308.1  protein maestro isoform X11

    5. XM_011247005.2XP_011245307.1  protein maestro isoform X10

    6. XM_017317980.1XP_017173469.1  protein maestro isoform X5

    7. XM_006526256.3XP_006526319.1  protein maestro isoform X8

    8. XM_006526254.3XP_006526317.1  protein maestro isoform X6

    9. XM_017317981.1XP_017173470.1  protein maestro isoform X9

    10. XM_006526249.3XP_006526312.1  protein maestro isoform X1

      Conserved Domains (1) summary
      sd00044
      Location:183211
      HEAT; HEAT repeat [structural motif]
    11. XM_006526250.3XP_006526313.1  protein maestro isoform X2

      Conserved Domains (2) summary
      pfam13646
      Location:185286
      HEAT_2; HEAT repeats
      sd00044
      Location:183211
      HEAT; HEAT repeat [structural motif]
    12. XM_006526251.3XP_006526314.1  protein maestro isoform X3

      Conserved Domains (1) summary
      sd00044
      Location:176208
      HEAT; HEAT repeat [structural motif]
    13. XM_006526252.3XP_006526315.1  protein maestro isoform X4

      Conserved Domains (1) summary
      sd00044
      Location:175207
      HEAT; HEAT repeat [structural motif]
    14. XM_006526260.3XP_006526323.1  protein maestro isoform X12

      See identical proteins and their annotated locations for XP_006526323.1

      UniProtKB/TrEMBL
      E9QNX2
      Conserved Domains (1) summary
      sd00044
      Location:4674
      HEAT; HEAT repeat [structural motif]
    15. XM_017317983.1XP_017173472.1  protein maestro isoform X15

      Conserved Domains (1) summary
      sd00044
      Location:941
      HEAT; HEAT repeat [structural motif]
    16. XM_006526261.3XP_006526324.1  protein maestro isoform X14

      Conserved Domains (1) summary
      sd00044
      Location:1042
      HEAT; HEAT repeat [structural motif]
    17. XM_006526262.3XP_006526325.1  protein maestro isoform X15

      Conserved Domains (1) summary
      sd00044
      Location:941
      HEAT; HEAT repeat [structural motif]
    18. XM_017317982.1XP_017173471.1  protein maestro isoform X13

      Conserved Domains (1) summary
      sd00044
      Location:2355
      HEAT; HEAT repeat [structural motif]
    19. XM_011247007.1XP_011245309.1  protein maestro isoform X13

      Conserved Domains (1) summary
      sd00044
      Location:2355
      HEAT; HEAT repeat [structural motif]
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