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    Nop56 NOP56 ribonucleoprotein [ Mus musculus (house mouse) ]

    Gene ID: 67134, updated on 19-May-2018
    Official Symbol
    Nop56provided by MGI
    Official Full Name
    NOP56 ribonucleoproteinprovided by MGI
    Primary source
    MGI:MGI:1914384
    See related
    Ensembl:ENSMUSG00000027405 Vega:OTTMUSG00000015495
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Nol5a; 2310044F10Rik
    Expression
    Broad expression in CNS E11.5 (RPKM 75.9), liver E14 (RPKM 61.1) and 23 other tissues See more
    Orthologs
    See Nop56 in Genome Data Viewer
    Location:
    2; 2 F1
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 2 NC_000068.7 (130274367..130279313)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 2 NC_000068.6 (130100148..130105049)

    Chromosome 2 - NC_000068.7Genomic Context describing neighboring genes Neighboring gene small nuclear ribonucleoprotein B Neighboring gene transmembrane channel-like gene family 2 Neighboring gene small nucleolar RNA, C/D box 110 Neighboring gene small nucleolar RNA, C/D box 57 Neighboring gene isocitrate dehydrogenase 3 (NAD+) beta Neighboring gene predicted gene, 30169 Neighboring gene early B cell factor 4 Neighboring gene predicted gene, 39936

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a
    Products Interactant Other Gene Complex Source Pubs Description

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    cadherin binding ISO
    Inferred from Sequence Orthology
    more info
     
    histone methyltransferase binding ISO
    Inferred from Sequence Orthology
    more info
     
    snoRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    snoRNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    ribosome biogenesis IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    box C/D snoRNP complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    fibrillar center ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    pre-snoRNP complex ISO
    Inferred from Sequence Orthology
    more info
     
    small nucleolar ribonucleoprotein complex ISO
    Inferred from Sequence Orthology
    more info
     
    small-subunit processome IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Preferred Names
    nucleolar protein 56
    Names
    56kDa with KKE/D repeat
    NOP56 ribonucleoprotein homolog
    nucleolar protein 5A

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_024193.2NP_077155.2  nucleolar protein 56

      See identical proteins and their annotated locations for NP_077155.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the protein-coding transcript.
      Source sequence(s)
      AI115137, AK150258, CJ162437
      Consensus CDS
      CCDS16737.1
      UniProtKB/Swiss-Prot
      Q9D6Z1
      Related
      ENSMUSP00000099487.4, OTTMUSP00000016508, ENSMUST00000103198.10, OTTMUST00000036787
      Conserved Domains (3) summary
      smart00931
      Location:168219
      NOSIC; NOSIC (NUC001) domain
      COG1498
      Location:48416
      SIK1; RNA processing factor Prp31, contains Nop domain [Translation, ribosomal structure and biogenesis]
      pfam08156
      Location:570
      NOP5NT; NOP5NT (NUC127) domain

    RNA

    1. NR_149733.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) contains an alternate exon in the 3' end compared to variant 1. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      AL833804

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000068.7 Reference GRCm38.p4 C57BL/6J

      Range
      130274367..130279313
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006500062.1XP_006500125.1  nucleolar protein 56 isoform X1

      Conserved Domains (3) summary
      smart00931
      Location:168219
      NOSIC; NOSIC (NUC001) domain
      COG1498
      Location:48416
      SIK1; RNA processing factor Prp31, contains Nop domain [Translation, ribosomal structure and biogenesis]
      pfam08156
      Location:570
      NOP5NT; NOP5NT (NUC127) domain

    RNA

    1. XR_866336.1 RNA Sequence

    2. XR_374509.2 RNA Sequence

    3. XR_866335.1 RNA Sequence

    4. XR_374507.2 RNA Sequence

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