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    Srpk3 serine/arginine-rich protein specific kinase 3 [ Mus musculus (house mouse) ]

    Gene ID: 56504, updated on 8-Apr-2018
    Official Symbol
    Srpk3provided by MGI
    Official Full Name
    serine/arginine-rich protein specific kinase 3provided by MGI
    Primary source
    MGI:MGI:1891338
    See related
    Ensembl:ENSMUSG00000002007 Vega:OTTMUSG00000017656
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Mssk1; Stk23
    Expression
    Biased expression in spleen adult (RPKM 23.8), heart adult (RPKM 14.3) and 12 other tissues See more
    Orthologs
    Location:
    X; X A7.3
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) X NC_000086.7 (73773994..73778925)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) X NC_000086.6 (71019761..71024264)

    Chromosome X - NC_000086.7Genomic Context describing neighboring genes Neighboring gene B cell receptor associated protein 31 Neighboring gene ATP-binding cassette, sub-family D (ALD), member 1 Neighboring gene plexin B3 Neighboring gene isocitrate dehydrogenase 3 (NAD+), gamma Neighboring gene signal sequence receptor, delta

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    Products Interactant Other Gene Complex Source Pubs Description

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    protein serine/threonine kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    protein serine/threonine kinase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    cell differentiation IEA
    Inferred from Electronic Annotation
    more info
     
    intracellular signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    multicellular organism development IEA
    Inferred from Electronic Annotation
    more info
     
    muscle organ development IEA
    Inferred from Electronic Annotation
    more info
     
    muscle tissue development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    phosphorylation IEA
    Inferred from Electronic Annotation
    more info
     
    protein phosphorylation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    regulation of gene expression IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    regulation of mRNA processing IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    skeletal muscle tissue development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    spliceosomal complex assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Preferred Names
    SRSF protein kinase 3
    Names
    SR-protein-specific kinase 3
    muscle-specific serine kinase 1
    serine/threonine kinase 23, muscle-specific serine kinase 1 70
    serine/threonine-protein kinase 23
    serine/threonine-protein kinase SRPK3
    NP_062658.1
    XP_006528235.1
    XP_017174068.1

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_019684.2NP_062658.1  SRSF protein kinase 3

      See identical proteins and their annotated locations for NP_062658.1

      Status: VALIDATED

      Source sequence(s)
      AF043288, BY243709
      Consensus CDS
      CCDS30211.1
      UniProtKB/Swiss-Prot
      Q9Z0G2
      UniProtKB/TrEMBL
      Q0VAW8
      Related
      ENSMUSP00000002081.5, OTTMUSP00000019243, ENSMUST00000002081.5, OTTMUST00000042854
      Conserved Domains (2) summary
      smart00220
      Location:78563
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd14218
      Location:67563
      STKc_SRPK3; Catalytic domain of the Serine/Threonine Kinase, Serine-aRginine Protein Kinase 3

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000086.7 Reference GRCm38.p4 C57BL/6J

      Range
      73773994..73778925
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017318579.1XP_017174068.1  SRSF protein kinase 3 isoform X2

    2. XM_006528172.3XP_006528235.1  SRSF protein kinase 3 isoform X1

      Conserved Domains (2) summary
      smart00220
      Location:102588
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd14218
      Location:91588
      STKc_SRPK3; Catalytic domain of the Serine/Threonine Kinase, Serine-aRginine Protein Kinase 3
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