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    ZDHHC24 zinc finger DHHC-type containing 24 [ Homo sapiens (human) ]

    Gene ID: 254359, updated on 8-Apr-2018
    Official Symbol
    ZDHHC24provided by HGNC
    Official Full Name
    zinc finger DHHC-type containing 24provided by HGNC
    Primary source
    HGNC:HGNC:27387
    See related
    Ensembl:ENSG00000174165 Vega:OTTHUMG00000167096
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Expression
    Ubiquitous expression in spleen (RPKM 1.8), kidney (RPKM 1.8) and 25 other tissues See more
    Orthologs
    See ZDHHC24 in Genome Data Viewer
    Location:
    11q13.2
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    109 current GRCh38.p12 (GCF_000001405.38) 11 NC_000011.10 (66520625..66546238, complement)
    105 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (66288854..66313709, complement)

    Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC101928069 Neighboring gene pellino E3 ubiquitin protein ligase family member 3 Neighboring gene skeletal muscle cis-regulatory module in DPP3 intron Neighboring gene dipeptidyl peptidase 3 Neighboring gene Bardet-Biedl syndrome 1 Neighboring gene actinin alpha 3 (gene/pseudogene) Neighboring gene cathepsin F

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Jun 15 11:32:44 2016

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    NHGRI GWAS Catalog

    Description
    Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4.
    NHGRI GWA Catalog
    Products Interactant Other Gene Complex Source Pubs Description

    Homology

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    protein-cysteine S-palmitoyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    protein-cysteine S-palmitoyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    peptidyl-L-cysteine S-palmitoylation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    protein targeting to membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    Golgi apparatus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    endoplasmic reticulum IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    Preferred Names
    probable palmitoyltransferase ZDHHC24
    Names
    DHHC-24
    zinc finger DHHC domain-containing protein 24
    zinc finger, DHHC domain containing 24
    NP_001335500.1
    NP_997223.1
    XP_005273931.1
    XP_011543195.1
    XP_011543196.1

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001348571.1NP_001335500.1  probable palmitoyltransferase ZDHHC24 isoform 2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 3' UTR and coding sequence compared to variant 1. The resulting isoform (2) has a shorter and distinct C-terminus compared to isoform 1.
      Source sequence(s)
      AK310561, DC406006
      UniProtKB/TrEMBL
      E9PLR9
      Related
      ENSP00000431321.1, ENST00000526986.5
      Conserved Domains (1) summary
      cl19890
      Location:95169
      zf-DHHC; DHHC palmitoyltransferase
    2. NM_207340.2NP_997223.1  probable palmitoyltransferase ZDHHC24 isoform 1

      See identical proteins and their annotated locations for NP_997223.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
      Source sequence(s)
      AP002748, AY358448, DC406006
      Consensus CDS
      CCDS8143.1
      UniProtKB/Swiss-Prot
      Q6UX98
      Related
      ENSP00000309429.3, OTTHUMP00000235141, ENST00000310442.4, OTTHUMT00000393089
      Conserved Domains (1) summary
      pfam01529
      Location:95234
      zf-DHHC; DHHC palmitoyltransferase

    RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p12 Primary Assembly

    Genomic

    1. NC_000011.10 Reference GRCh38.p12 Primary Assembly

      Range
      66520625..66546238 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005273874.4XP_005273931.1  probable palmitoyltransferase ZDHHC24 isoform X2

      See identical proteins and their annotated locations for XP_005273931.1

      UniProtKB/TrEMBL
      E9PI61
      Related
      ENSP00000436503.1, OTTHUMP00000235139, ENST00000534073.5
      Conserved Domains (1) summary
      cl19890
      Location:95169
      zf-DHHC; DHHC palmitoyltransferase
    2. XM_011544894.2XP_011543196.1  probable palmitoyltransferase ZDHHC24 isoform X2

      See identical proteins and their annotated locations for XP_011543196.1

      UniProtKB/TrEMBL
      E9PI61
      Conserved Domains (1) summary
      cl19890
      Location:95169
      zf-DHHC; DHHC palmitoyltransferase
    3. XM_011544893.3XP_011543195.1  probable palmitoyltransferase ZDHHC24 isoform X1

      Conserved Domains (1) summary
      cl19890
      Location:95169
      zf-DHHC; DHHC palmitoyltransferase

    RNA

    1. XR_001747823.2 RNA Sequence

    2. XR_949860.3 RNA Sequence

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