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    St8sia3 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3 [ Mus musculus (house mouse) ]

    Gene ID: 20451, updated on 27-Jan-2018
    Official Symbol
    St8sia3provided by MGI
    Official Full Name
    ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3provided by MGI
    Primary source
    MGI:MGI:106019
    See related
    Ensembl:ENSMUSG00000056812 Vega:OTTMUSG00000028204
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Siat8c; AI847333; ST8SiaIII
    Expression
    Biased expression in cortex adult (RPKM 10.9), CNS E18 (RPKM 10.3) and 8 other tissues See more
    Orthologs
    Location:
    18; 18 E1
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 18 NC_000084.6 (64254359..64276144)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 18 NC_000084.5 (64414013..64435798)

    Chromosome 18 - NC_000084.6Genomic Context describing neighboring genes Neighboring gene ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3, opposite strand Neighboring gene NADH dehydrogenase (ubiquinone) 1 beta subcomplex 3 pseudogene Neighboring gene peroxiredoxin 1, pseudogene 1 Neighboring gene ribosomal protein S15, pseudogene 3 Neighboring gene one cut domain, family member 2

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity ISO
    Inferred from Sequence Orthology
    more info
     
    identical protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    sialyltransferase activity ISO
    Inferred from Sequence Orthology
    more info
     
    transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    transferase activity, transferring glycosyl groups IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    N-glycan processing ISO
    Inferred from Sequence Orthology
    more info
     
    ganglioside biosynthetic process ISO
    Inferred from Sequence Orthology
    more info
     
    glycoprotein metabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    oligosaccharide metabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    protein glycosylation ISO
    Inferred from Sequence Orthology
    more info
     
    protein sialylation ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    Golgi apparatus IEA
    Inferred from Electronic Annotation
    more info
     
    integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    membrane IEA
    Inferred from Electronic Annotation
    more info
     
    Preferred Names
    sia-alpha-2,3-Gal-beta-1,4-GlcNAc-R:alpha 2,8-sialyltransferase
    Names
    SIAT8-C
    alpha-2,8-sialyltransferase 8C
    alpha-2,8-sialyltransferase III
    sialyltransferase 8 (alpha-2, 8-sialyltransferase) C
    sialyltransferase 8C
    sialyltransferase St8Sia III
    sialytransferase St8Sia III
    NP_033208.2

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_009182.3NP_033208.2  sia-alpha-2,3-Gal-beta-1,4-GlcNAc-R:alpha 2,8-sialyltransferase

      See identical proteins and their annotated locations for NP_033208.2

      Status: VALIDATED

      Source sequence(s)
      AK015874, BB616760, BC075645
      Consensus CDS
      CCDS29301.1
      UniProtKB/Swiss-Prot
      Q64689
      UniProtKB/TrEMBL
      Q9CUJ6
      Related
      ENSMUSP00000025477.7, OTTMUSP00000035540, ENSMUST00000025477.13, OTTMUST00000069864
      Conserved Domains (1) summary
      pfam00777
      Location:113376
      Glyco_transf_29; Glycosyltransferase family 29 (sialyltransferase)

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000084.6 Reference GRCm38.p4 C57BL/6J

      Range
      64254359..64276144
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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