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    Odc1 ornithine decarboxylase, structural 1 [ Mus musculus (house mouse) ]

    Gene ID: 18263, updated on 14-Apr-2018
    Official Symbol
    Odc1provided by MGI
    Official Full Name
    ornithine decarboxylase, structural 1provided by MGI
    Primary source
    MGI:MGI:97402
    See related
    Ensembl:ENSMUSG00000011179
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    ODC
    Expression
    Broad expression in liver E14 (RPKM 226.2), liver E14.5 (RPKM 221.0) and 28 other tissues See more
    Orthologs
    Location:
    12 A1.1; 12 8.11 cM
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 12 NC_000078.6 (17544867..17551502)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 12 NC_000078.5 (17551679..17558308)

    Chromosome 12 - NC_000078.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 36752 Neighboring gene predicted gene, 46325 Neighboring gene predicted gene, 36862 Neighboring gene predicted gene, 29864

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    Products Interactant Other Gene Complex Source Pubs Description

    Markers

    Homology

    Clone Names

    • MGC103389

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    carboxy-lyase activity IEA
    Inferred from Electronic Annotation
    more info
     
    catalytic activity IEA
    Inferred from Electronic Annotation
    more info
     
    lyase activity IEA
    Inferred from Electronic Annotation
    more info
     
    ornithine decarboxylase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    ornithine decarboxylase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    ornithine decarboxylase activity ISO
    Inferred from Sequence Orthology
    more info
     
    protein homodimerization activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Process Evidence Code Pubs
    kidney development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    polyamine biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
     
    polyamine metabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of cell proliferation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    putrescine biosynthetic process ISO
    Inferred from Sequence Orthology
    more info
     
    putrescine biosynthetic process from ornithine IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    putrescine biosynthetic process from ornithine IDA
    Inferred from Direct Assay
    more info
    PubMed 
    regulation of protein catabolic process IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Component Evidence Code Pubs
    cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    cytosol IDA
    Inferred from Direct Assay
    more info
    PubMed 
    perinuclear region of cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    Preferred Names
    ornithine decarboxylase
    NP_038642.2
    XP_017170479.1

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_013614.2NP_038642.2  ornithine decarboxylase

      See identical proteins and their annotated locations for NP_038642.2

      Status: VALIDATED

      Source sequence(s)
      AC163651
      Consensus CDS
      CCDS25829.1
      UniProtKB/Swiss-Prot
      P00860
      Related
      ENSMUSP00000128661.1, ENSMUST00000171737.2
      Conserved Domains (2) summary
      cd00622
      Location:37408
      PLPDE_III_ODC; Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Ornithine Decarboxylase
      COG0019
      Location:40408
      LysA; Diaminopimelate decarboxylase [Amino acid transport and metabolism]

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000078.6 Reference GRCm38.p4 C57BL/6J

      Range
      17544867..17551502
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017314990.1XP_017170479.1  ornithine decarboxylase isoform X1

      UniProtKB/Swiss-Prot
      P00860
      Conserved Domains (2) summary
      cd00622
      Location:37408
      PLPDE_III_ODC; Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Ornithine Decarboxylase
      COG0019
      Location:40408
      LysA; Diaminopimelate decarboxylase [Amino acid transport and metabolism]
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