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    TTC16 tetratricopeptide repeat domain 16 [ Homo sapiens (human) ]

    Gene ID: 158248, updated on 29-Mar-2018
    Official Symbol
    TTC16provided by HGNC
    Official Full Name
    tetratricopeptide repeat domain 16provided by HGNC
    Primary source
    HGNC:HGNC:26536
    See related
    Ensembl:ENSG00000167094 Vega:OTTHUMG00000020711
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Expression
    Biased expression in testis (RPKM 9.1), lung (RPKM 0.9) and 2 other tissues See more
    Orthologs
    Location:
    9q34.11
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    109 current GRCh38.p12 (GCF_000001405.38) 9 NC_000009.12 (127716064..127731600)
    105 previous assembly GRCh37.p13 (GCF_000001405.25) 9 NC_000009.11 (130478358..130493879)

    Chromosome 9 - NC_000009.12Genomic Context describing neighboring genes Neighboring gene syntaxin binding protein 1 Neighboring gene microRNA 3911 Neighboring gene peptidyl-tRNA hydrolase 1 homolog Neighboring gene cilia and flagella associated protein 157 Neighboring gene torsin family 2 member A Neighboring gene SH2 domain containing 3C Neighboring gene uncharacterized LOC107987132 Neighboring gene microRNA 3960 Neighboring gene microRNA 2861 Neighboring gene cyclin dependent kinase 9

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Jun 15 11:32:44 2016

    Markers

    Homology

    Clone Names

    • FLJ32780
    Preferred Names
    tetratricopeptide repeat protein 16
    Names
    TPR repeat protein 16

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001317037.1NP_001303966.1  tetratricopeptide repeat protein 16 isoform 2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) uses an alternate in-frame splice junction in the 5' end compared to variant 1. The resulting isoform (2) has the same N- and C-termini but is shorter compared to isoform 1.
      Source sequence(s)
      AK057342, AK294862, AK302737
      UniProtKB/Swiss-Prot
      Q8NEE8
      UniProtKB/TrEMBL
      B4DH05, B4DZ42
      Conserved Domains (4) summary
      sd00006
      Location:320346
      TPR; TPR repeat [structural motif]
      pfam00515
      Location:355385
      TPR_1; Tetratricopeptide repeat
      pfam05338
      Location:71130
      DUF717; Protein of unknown function (DUF717)
      pfam13414
      Location:319383
      TPR_11; TPR repeat
    2. NM_144965.2NP_659402.1  tetratricopeptide repeat protein 16 isoform 1

      See identical proteins and their annotated locations for NP_659402.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
      Source sequence(s)
      AK057342, AK294862
      Consensus CDS
      CCDS6875.1
      UniProtKB/Swiss-Prot
      Q8NEE8
      UniProtKB/TrEMBL
      B4DH05
      Related
      ENSP00000362386.3, OTTHUMP00000022195, ENST00000373289.3, OTTHUMT00000054224
      Conserved Domains (3) summary
      sd00006
      Location:333359
      TPR; TPR repeat [structural motif]
      pfam00515
      Location:368398
      TPR_1; Tetratricopeptide repeat
      pfam13414
      Location:62124
      TPR_11; TPR repeat

    RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p12 Primary Assembly

    Genomic

    1. NC_000009.12 Reference GRCh38.p12 Primary Assembly

      Range
      127716064..127731600
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011518292.2XP_011516594.1  tetratricopeptide repeat protein 16 isoform X7

      See identical proteins and their annotated locations for XP_011516594.1

      Conserved Domains (2) summary
      PHA03247
      Location:40292
      PHA03247; large tegument protein UL36; Provisional
      COG5099
      Location:391569
      COG5099; RNA-binding protein of the Puf family, translational repressor [Translation, ribosomal structure and biogenesis]
    2. XM_011518284.2XP_011516586.1  tetratricopeptide repeat protein 16 isoform X2

      Conserved Domains (4) summary
      COG0457
      Location:70348
      TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
      sd00006
      Location:285311
      TPR; TPR repeat [structural motif]
      pfam00515
      Location:320350
      TPR_1; Tetratricopeptide repeat
      pfam13414
      Location:319389
      TPR_11; TPR repeat
    3. XM_011518288.2XP_011516590.1  tetratricopeptide repeat protein 16 isoform X4

      Conserved Domains (3) summary
      sd00006
      Location:156184
      TPR; TPR repeat [structural motif]
      pfam13371
      Location:212277
      TPR_9; Tetratricopeptide repeat
      pfam13414
      Location:62119
      TPR_11; TPR repeat
    4. XM_011518290.2XP_011516592.1  tetratricopeptide repeat protein 16 isoform X6

      See identical proteins and their annotated locations for XP_011516592.1

      Conserved Domains (3) summary
      sd00006
      Location:155181
      TPR; TPR repeat [structural motif]
      pfam00515
      Location:190220
      TPR_1; Tetratricopeptide repeat
      pfam13414
      Location:154218
      TPR_11; TPR repeat
    5. XM_011518291.2XP_011516593.1  tetratricopeptide repeat protein 16 isoform X7

      See identical proteins and their annotated locations for XP_011516593.1

      Conserved Domains (2) summary
      PHA03247
      Location:40292
      PHA03247; large tegument protein UL36; Provisional
      COG5099
      Location:391569
      COG5099; RNA-binding protein of the Puf family, translational repressor [Translation, ribosomal structure and biogenesis]
    6. XM_005251734.2XP_005251791.1  tetratricopeptide repeat protein 16 isoform X8

      Conserved Domains (2) summary
      sd00006
      Location:222252
      TPR; TPR repeat [structural motif]
      pfam13414
      Location:202254
      TPR_11; TPR repeat
    7. XM_011518285.2XP_011516587.1  tetratricopeptide repeat protein 16 isoform X3

      Conserved Domains (4) summary
      sd00006
      Location:6189
      TPR; TPR repeat [structural motif]
      cd15830
      Location:61149
      BamD; BamD lipoprotein, a component of the beta-barrel assembly machinery
      pfam13371
      Location:260325
      TPR_9; Tetratricopeptide repeat
      pfam13414
      Location:62124
      TPR_11; TPR repeat
    8. XM_006716970.2XP_006717033.1  tetratricopeptide repeat protein 16 isoform X6

      See identical proteins and their annotated locations for XP_006717033.1

      Conserved Domains (3) summary
      sd00006
      Location:155181
      TPR; TPR repeat [structural motif]
      pfam00515
      Location:190220
      TPR_1; Tetratricopeptide repeat
      pfam13414
      Location:154218
      TPR_11; TPR repeat
    9. XM_005251733.2XP_005251790.1  tetratricopeptide repeat protein 16 isoform X5

      Conserved Domains (3) summary
      sd00006
      Location:157183
      TPR; TPR repeat [structural motif]
      pfam00515
      Location:192222
      TPR_1; Tetratricopeptide repeat
      pfam13414
      Location:156220
      TPR_11; TPR repeat
    10. XM_006716971.2XP_006717034.1  tetratricopeptide repeat protein 16 isoform X6

      See identical proteins and their annotated locations for XP_006717034.1

      Conserved Domains (3) summary
      sd00006
      Location:155181
      TPR; TPR repeat [structural motif]
      pfam00515
      Location:190220
      TPR_1; Tetratricopeptide repeat
      pfam13414
      Location:154218
      TPR_11; TPR repeat
    11. XM_011518283.2XP_011516585.1  tetratricopeptide repeat protein 16 isoform X1

      Conserved Domains (3) summary
      sd00006
      Location:333359
      TPR; TPR repeat [structural motif]
      pfam00515
      Location:368398
      TPR_1; Tetratricopeptide repeat
      pfam13414
      Location:62124
      TPR_11; TPR repeat
    12. XM_011518293.2XP_011516595.1  tetratricopeptide repeat protein 16 isoform X9

      Conserved Domains (3) summary
      sd00006
      Location:333359
      TPR; TPR repeat [structural motif]
      pfam00515
      Location:368398
      TPR_1; Tetratricopeptide repeat
      pfam13414
      Location:62124
      TPR_11; TPR repeat
    13. XM_011518295.2XP_011516597.1  tetratricopeptide repeat protein 16 isoform X11

      Conserved Domains (3) summary
      sd00006
      Location:333359
      TPR; TPR repeat [structural motif]
      pfam00515
      Location:368398
      TPR_1; Tetratricopeptide repeat
      pfam13414
      Location:62124
      TPR_11; TPR repeat
    14. XM_011518294.3XP_011516596.1  tetratricopeptide repeat protein 16 isoform X10

      Conserved Domains (3) summary
      sd00006
      Location:333359
      TPR; TPR repeat [structural motif]
      pfam00515
      Location:368398
      TPR_1; Tetratricopeptide repeat
      pfam13414
      Location:62124
      TPR_11; TPR repeat
    15. XM_011518297.2XP_011516599.1  tetratricopeptide repeat protein 16 isoform X12

      Conserved Domains (3) summary
      sd00006
      Location:333359
      TPR; TPR repeat [structural motif]
      pfam00515
      Location:368398
      TPR_1; Tetratricopeptide repeat
      pfam13414
      Location:62124
      TPR_11; TPR repeat
    16. XM_011518298.3XP_011516600.1  tetratricopeptide repeat protein 16 isoform X13

      Conserved Domains (3) summary
      sd00006
      Location:6189
      TPR; TPR repeat [structural motif]
      pfam00515
      Location:368398
      TPR_1; Tetratricopeptide repeat
      pfam13414
      Location:62124
      TPR_11; TPR repeat
    17. XM_011518289.3XP_011516591.1  tetratricopeptide repeat protein 16 isoform X6

      See identical proteins and their annotated locations for XP_011516591.1

      Conserved Domains (3) summary
      sd00006
      Location:155181
      TPR; TPR repeat [structural motif]
      pfam00515
      Location:190220
      TPR_1; Tetratricopeptide repeat
      pfam13414
      Location:154218
      TPR_11; TPR repeat

    RNA

    1. XR_002956761.1 RNA Sequence

    2. XR_929722.2 RNA Sequence

    3. XR_001746193.2 RNA Sequence

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