Format

Send to:

Choose Destination
    • Showing Current items.

    LRRC74A leucine rich repeat containing 74A [ Homo sapiens (human) ]

    Gene ID: 145497, updated on 27-Jan-2018
    Official Symbol
    LRRC74Aprovided by HGNC
    Official Full Name
    leucine rich repeat containing 74Aprovided by HGNC
    Primary source
    HGNC:HGNC:23346
    See related
    Ensembl:ENSG00000100565 Vega:OTTHUMG00000150153
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    LRRC74; C14orf166B
    Expression
    Restricted expression toward testis (RPKM 2.8) See more
    Orthologs
    Location:
    14q24.3
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    108 current GRCh38.p7 (GCF_000001405.33) 14 NC_000014.9 (76826370..76870302)
    105 previous assembly GRCh37.p13 (GCF_000001405.25) 14 NC_000014.8 (77292725..77336656)

    Chromosome 14 - NC_000014.9Genomic Context describing neighboring genes Neighboring gene vasohibin 1 Neighboring gene VASH1 antisense RNA 1 Neighboring gene angel homolog 1 Neighboring gene RNA, 7SK small nuclear pseudogene 17 Neighboring gene ribosomal protein L22 pseudogene 2

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Jun 15 11:32:44 2016

    Markers

    Homology

    Preferred Names
    leucine-rich repeat-containing protein 74A
    Names
    leucine rich repeat containing 74
    leucine-rich repeat-containing protein 74

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_194287.2NP_919263.2  leucine-rich repeat-containing protein 74A

      See identical proteins and their annotated locations for NP_919263.2

      Status: VALIDATED

      Source sequence(s)
      AF111169, BC121159, DB337977, DC397584
      Consensus CDS
      CCDS9853.2
      UniProtKB/Swiss-Prot
      Q0VAA2
      Related
      ENSP00000377369.3, OTTHUMP00000196473, ENST00000393774.7, OTTHUMT00000316592
      Conserved Domains (2) summary
      cd00116
      Location:112368
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
      sd00033
      Location:136158
      LRR_RI; leucine-rich repeat [structural motif]

    RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 108

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p7 Primary Assembly

    Genomic

    1. NC_000014.9 Reference GRCh38.p7 Primary Assembly

      Range
      76826370..76870302
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017021035.1XP_016876524.1  leucine-rich repeat-containing protein 74A isoform X5

    2. XM_017021034.1XP_016876523.1  leucine-rich repeat-containing protein 74A isoform X3

    3. XM_017021032.1XP_016876521.1  leucine-rich repeat-containing protein 74A isoform X1

      Conserved Domains (2) summary
      cd00116
      Location:128384
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
      sd00033
      Location:152174
      LRR_RI; leucine-rich repeat [structural motif]
    4. XM_011536479.1XP_011534781.1  leucine-rich repeat-containing protein 74A isoform X1

      Conserved Domains (2) summary
      cd00116
      Location:128384
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
      sd00033
      Location:152174
      LRR_RI; leucine-rich repeat [structural motif]
    5. XM_011536483.1XP_011534785.1  leucine-rich repeat-containing protein 74A isoform X4

      Conserved Domains (2) summary
      cd00116
      Location:128384
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
      sd00033
      Location:152174
      LRR_RI; leucine-rich repeat [structural motif]
    6. XM_017021033.1XP_016876522.1  leucine-rich repeat-containing protein 74A isoform X2

    7. XM_017021036.1XP_016876525.1  leucine-rich repeat-containing protein 74A isoform X6

    8. XM_011536487.1XP_011534789.1  leucine-rich repeat-containing protein 74A isoform X10

      Conserved Domains (3) summary
      cd00116
      Location:128291
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
      sd00033
      Location:152178
      LRR_RI; leucine-rich repeat [structural motif]
      pfam08068
      Location:1036
      DKCLD; DKCLD (NUC011) domain
    9. XM_017021038.1XP_016876527.1  leucine-rich repeat-containing protein 74A isoform X7

    10. XM_017021037.1XP_016876526.1  leucine-rich repeat-containing protein 74A isoform X7

    11. XM_017021039.1XP_016876528.1  leucine-rich repeat-containing protein 74A isoform X8

    12. XM_017021040.1XP_016876529.1  leucine-rich repeat-containing protein 74A isoform X9

    13. XM_017021041.1XP_016876530.1  leucine-rich repeat-containing protein 74A isoform X11

    Alternate CHM1_1.1

    Genomic

    1. NC_018925.2 Alternate CHM1_1.1

      Range
      77230493..77274426
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Support Center