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    KRTAP10-6 keratin associated protein 10-6 [ Homo sapiens (human) ]

    Gene ID: 386674, updated on 29-Mar-2018

    Summary

    Official Symbol
    KRTAP10-6provided by HGNC
    Official Full Name
    keratin associated protein 10-6provided by HGNC
    Primary source
    HGNC:HGNC:20523
    See related
    Ensembl:ENSG00000188155 Vega:OTTHUMG00000057634
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    KAP10.6; KAP18.6; KRTAP18-6; KRTAP18.6
    Orthologs

    Genomic context

    See KRTAP10-6 in Genome Data Viewer
    Location:
    21q22.3
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    109 current GRCh38.p12 (GCF_000001405.38) 21 NC_000021.9 (44591268..44592505, complement)
    105 previous assembly GRCh37.p13 (GCF_000001405.25) 21 NC_000021.8 (46011149..46012386, complement)

    Chromosome 21 - NC_000021.9Genomic Context describing neighboring genes Neighboring gene thrombospondin type laminin G domain and EAR repeats Neighboring gene keratin associated protein 10-4 Neighboring gene keratin associated protein 10-5 Neighboring gene keratin associated protein 10-7 Neighboring gene keratin associated protein 10-8

    Genomic regions, transcripts, and products

    Pathways from BioSystems

    • Developmental Biology, organism-specific biosystem (from REACTOME)
      Developmental Biology, organism-specific biosystemAs a first step towards capturing the array of processes by which a fertilized egg gives rise to the diverse tissues of the body, examples of three kinds of processes have been annotated. These are a...
    • Keratinization, organism-specific biosystem (from REACTOME)
      Keratinization, organism-specific biosystemKeratins are the major structural protein of vertebrate epidermis, constituting up to 85% of a fully differentiated keratinocyte (Fuchs 1995). Keratins belong to a superfamily of intermediate filamen...

    General gene information

    Homology

    Gene Ontology Provided by GOA

    Process Evidence Code Pubs
    keratinization TAS
    Traceable Author Statement
    more info
     
    Component Evidence Code Pubs
    cytosol TAS
    Traceable Author Statement
    more info
     
    keratin filament IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    keratin-associated protein 10-6
    Names
    high sulfur keratin-associated protein 10.6
    keratin associated protein 18-6

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_198688.3NP_941961.3  keratin-associated protein 10-6

      See identical proteins and their annotated locations for NP_941961.3

      Status: VALIDATED

      Source sequence(s)
      AB076353
      Consensus CDS
      CCDS42959.1
      UniProtKB/Swiss-Prot
      P60371
      Related
      ENSP00000383219.1, OTTHUMP00000063330, ENST00000400368.1, OTTHUMT00000128037
      Conserved Domains (2) summary
      pfam01500
      Location:46204
      Keratin_B2; Keratin, high sulfur B2 protein
      pfam13885
      Location:89130
      Keratin_B2_2; Keratin, high sulfur B2 protein

    RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p12 Primary Assembly

    Genomic

    1. NC_000021.9 Reference GRCh38.p12 Primary Assembly

      Range
      44591268..44592505 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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