Format

Send to:

Choose Destination
    • Showing Current items.

    CTBP2 C-terminal binding protein 2 [ Homo sapiens (human) ]

    Gene ID: 1488, updated on 7-Oct-2018

    Summary

    Official Symbol
    CTBP2provided by HGNC
    Official Full Name
    C-terminal binding protein 2provided by HGNC
    Primary source
    HGNC:HGNC:2495
    See related
    Ensembl:ENSG00000175029 MIM:602619; Vega:OTTHUMG00000019224
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Summary
    This gene produces alternative transcripts encoding two distinct proteins. One protein is a transcriptional repressor, while the other isoform is a major component of specialized synapses known as synaptic ribbons. Both proteins contain a NAD+ binding domain similar to NAD+-dependent 2-hydroxyacid dehydrogenases. A portion of the 3' untranslated region was used to map this gene to chromosome 21q21.3; however, it was noted that similar loci elsewhere in the genome are likely. Blast analysis shows that this gene is present on chromosome 10. Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Feb 2014]
    Expression
    Ubiquitous expression in thyroid (RPKM 13.6), endometrium (RPKM 9.4) and 24 other tissues See more
    Orthologs

    Genomic context

    See CTBP2 in Genome Data Viewer
    Location:
    10q26.13
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    109 current GRCh38.p12 (GCF_000001405.38) 10 NC_000010.11 (124987849..125161061, complement)
    105 previous assembly GRCh37.p13 (GCF_000001405.25) 10 NC_000010.10 (126676418..126849624, complement)

    Chromosome 10 - NC_000010.11Genomic Context describing neighboring genes Neighboring gene nucleophosmin 1 pseudogene 31 Neighboring gene zinc finger RANBP2-type containing 1 Neighboring gene microRNA 4296 Neighboring gene mitochondrial ribosomal protein S21 pseudogene 6 Neighboring gene VISTA enhancer hs330

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Jun 15 11:32:44 2016

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Phenotypes

    NHGRI GWAS Catalog

    Description
    Meta-analysis of genome-wide association studies of adult height in East Asians identifies 17 novel loci.
    NHGRI GWA Catalog
    Multiple loci identified in a genome-wide association study of prostate cancer.
    NHGRI GWA Catalog
    Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche.
    NHGRI GWA Catalog

    Pathways from BioSystems

    • Chronic myeloid leukemia, organism-specific biosystem (from KEGG)
      Chronic myeloid leukemia, organism-specific biosystemChronic myeloid leukemia (CML) is a clonal myeloproliferative disorder of a pluripotent stem cell. The natural history of CML has a triphasic clinical course comprising of an initial chronic phase (C...
    • Chronic myeloid leukemia, conserved biosystem (from KEGG)
      Chronic myeloid leukemia, conserved biosystemChronic myeloid leukemia (CML) is a clonal myeloproliferative disorder of a pluripotent stem cell. The natural history of CML has a triphasic clinical course comprising of an initial chronic phase (C...
    • Degradation of beta-catenin by the destruction complex, organism-specific biosystem (from REACTOME)
      Degradation of beta-catenin by the destruction complex, organism-specific biosystemThe beta-catenin destruction complex plays a key role in the canonical Wnt signaling pathway. In the absence of Wnt signaling, this complex controls the levels of cytoplamic beta-catenin. Beta-cateni...
    • Disease, organism-specific biosystem (from REACTOME)
      Disease, organism-specific biosystemBiological processes are captured in Reactome by identifying the molecules (DNA, RNA, protein, small molecules) involved in them and describing the details of their interactions. From this molecular ...
    • Diseases of signal transduction, organism-specific biosystem (from REACTOME)
      Diseases of signal transduction, organism-specific biosystemSignaling processes are central to human physiology (e.g., Pires-da Silva & Sommer 2003), and their disruption by either germ-line and somatic mutation can lead to serious disease. Here, the molecula...
    • Endoderm Differentiation, organism-specific biosystem (from WikiPathways)
      Endoderm Differentiation, organism-specific biosystemModel depicting endoderm specification based on the literature and highly enriched gene expression profiles via comparison across dozens of independent induced and embryonic pluripotent stem cell lin...
    • Mesodermal Commitment Pathway, organism-specific biosystem (from WikiPathways)
      Mesodermal Commitment Pathway, organism-specific biosystemModel depicting mesodermal specification based on the literature and highly enriched gene expression profiles via comparison across dozens of independent induced and embryonic pluripotent stem cell l...
    • Neural Crest Differentiation, organism-specific biosystem (from WikiPathways)
      Neural Crest Differentiation, organism-specific biosystemGene regulatory network model of cranial neural crest cell (CNCC) development, adaped from PMID: 19575671. Most interactions in the model are proposed to regulate transcription of core factors involv...
    • Notch Signaling Pathway, organism-specific biosystem (from WikiPathways)
      Notch Signaling Pathway, organism-specific biosystemThe Notch signaling pathway is an evolutionarily conserved, intercellular signaling mechanism essential for proper embryonic development in all metazoan organisms in the Animal kingdom. The Notch pro...
    • Notch signaling pathway, organism-specific biosystem (from KEGG)
      Notch signaling pathway, organism-specific biosystemThe Notch signaling pathway is an evolutionarily conserved, intercellular signaling mechanism essential for proper embryonic development in all metazoan organisms in the Animal kingdom. The Notch pro...
    • Notch signaling pathway, conserved biosystem (from KEGG)
      Notch signaling pathway, conserved biosystemThe Notch signaling pathway is an evolutionarily conserved, intercellular signaling mechanism essential for proper embryonic development in all metazoan organisms in the Animal kingdom. The Notch pro...
    • Pathways in cancer, organism-specific biosystem (from KEGG)
      Pathways in cancer, organism-specific biosystem
      Pathways in cancer
    • Repression of WNT target genes, organism-specific biosystem (from REACTOME)
      Repression of WNT target genes, organism-specific biosystemIn the absence of a WNT signal, many WNT target genes are repressed by Groucho/TLE. Groucho was initially identified in Drosophila, where it has been shown to interact with a variety of proteins to ...
    • Signal Transduction, organism-specific biosystem (from REACTOME)
      Signal Transduction, organism-specific biosystemSignal transduction is a process in which extracellular signals elicit changes in cell state and activity. Transmembrane receptors sense changes in the cellular environment by binding ligands, such a...
    • Signaling by WNT in cancer, organism-specific biosystem (from REACTOME)
      Signaling by WNT in cancer, organism-specific biosystemThe WNT signaling pathway has been linked with cancer ever since the identification of the first WNT as a gene activated by integration of mouse mammary tumor virus proviral DNA in virally-induced br...
    • Signaling by Wnt, organism-specific biosystem (from REACTOME)
      Signaling by Wnt, organism-specific biosystemWNT signaling pathways control a wide range of developmental and adult process in metozoans including cell proliferation, cell fate decisions, cell polarity and stem cell maintenance (reviewed in Sai...
    • TCF7L2 mutants don't bind CTBP, organism-specific biosystem (from REACTOME)
      TCF7L2 mutants don't bind CTBP, organism-specific biosystem~50% of colorectal cancers with microsatellite instability show frameshift mutations in TCF7L2 that result in the loss of the CTBP-binding region (Duval et al, 1999; Cuillliere-Dartigues et al, 2006)...
    • Wnt Signaling Pathway and Pluripotency, organism-specific biosystem (from WikiPathways)
      Wnt Signaling Pathway and Pluripotency, organism-specific biosystemThis pathway was adapted from several resources and is designed to provide a theoretical frame-work for examining Wnt signaling and interacting components in the context of embryonic stem-cell plurip...
    • Wnt signaling pathway, organism-specific biosystem (from KEGG)
      Wnt signaling pathway, organism-specific biosystemWnt proteins are secreted morphogens that are required for basic developmental processes, such as cell-fate specification, progenitor-cell proliferation and the control of asymmetric cell division, i...
    • Wnt signaling pathway, conserved biosystem (from KEGG)
      Wnt signaling pathway, conserved biosystemWnt proteins are secreted morphogens that are required for basic developmental processes, such as cell-fate specification, progenitor-cell proliferation and the control of asymmetric cell division, i...

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    NAD binding IEA
    Inferred from Electronic Annotation
    more info
     
    chromatin binding IEA
    Inferred from Electronic Annotation
    more info
     
    oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor IEA
    Inferred from Electronic Annotation
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    protein kinase binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    protein-containing complex binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    retinoic acid receptor binding IEA
    Inferred from Electronic Annotation
    more info
     
    structural constituent of presynaptic active zone IEA
    Inferred from Electronic Annotation
    more info
     
    transcription coactivator activity IEA
    Inferred from Electronic Annotation
    more info
     
    transcription corepressor activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    cellular response to leukemia inhibitory factor IEA
    Inferred from Electronic Annotation
    more info
     
    maintenance of presynaptic active zone structure IEA
    Inferred from Electronic Annotation
    more info
     
    negative regulation of cell proliferation TAS
    Traceable Author Statement
    more info
    PubMed 
    negative regulation of transcription, DNA-templated ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    oxidation-reduction process IEA
    Inferred from Electronic Annotation
    more info
     
    positive regulation of chromatin binding IEA
    Inferred from Electronic Annotation
    more info
     
    positive regulation of retinoic acid receptor signaling pathway IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of transcription by RNA polymerase II IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    synaptic vesicle docking IEA
    Inferred from Electronic Annotation
    more info
     
    viral genome replication TAS
    Traceable Author Statement
    more info
    PubMed 
    white fat cell differentiation ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    GABA-ergic synapse IEA
    Inferred from Electronic Annotation
    more info
     
    cell junction IEA
    Inferred from Electronic Annotation
    more info
     
    glutamatergic synapse IEA
    Inferred from Electronic Annotation
    more info
     
    nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    photoreceptor ribbon synapse IEA
    Inferred from Electronic Annotation
    more info
     
    presynaptic active zone cytoplasmic component IEA
    Inferred from Electronic Annotation
    more info
     
    presynaptic cytosol IEA
    Inferred from Electronic Annotation
    more info
     
    transcriptional repressor complex ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    General protein information

    Preferred Names
    C-terminal-binding protein 2
    Names
    ribeye

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001083914.2NP_001077383.1  C-terminal-binding protein 2 isoform 1

      See identical proteins and their annotated locations for NP_001077383.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (3) contains a distinct 5' UTR and 5' CDS, compared to variant 2. Variants 1, 3, 4, and 5-8 all encode the same isoform (1), which has a distinct N-terminus that is 540 aa shorter than the N-terminus of isoform 2. The protein is thought to bind to the C-terminus of the adenovirus E1A proteins. Studies in mice suggest that this protein is involved in transcriptional repression.
      Source sequence(s)
      AL731571, BC047018, DB456766
      Consensus CDS
      CCDS7643.1
      UniProtKB/Swiss-Prot
      P56545
      Related
      ENSP00000410474.2, OTTHUMP00000235910, ENST00000411419.6, OTTHUMT00000394563
      Conserved Domains (1) summary
      cd05299
      Location:34352
      CtBP_dh; C-terminal binding protein (CtBP), D-isomer-specific 2-hydroxyacid dehydrogenases related repressor
    2. NM_001290214.2NP_001277143.1  C-terminal-binding protein 2 isoform 1

      See identical proteins and their annotated locations for NP_001277143.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (4) contains a distinct 5' UTR and 5' CDS, compared to variant 2. Variants 1, 3, 4, and 5-8 all encode the same isoform (1), which has a distinct N-terminus that is 540 aa shorter than the N-terminus of isoform 2. The protein is thought to bind to the C-terminus of the adenovirus E1A proteins. Studies in mice suggest that this protein is involved in transcriptional repression.
      Source sequence(s)
      AL731571, BC052276, BM712328
      Consensus CDS
      CCDS7643.1
      UniProtKB/Swiss-Prot
      P56545
      Related
      ENSP00000436285.1, OTTHUMP00000235909, ENST00000494626.6, OTTHUMT00000050901
      Conserved Domains (1) summary
      cd05299
      Location:34352
      CtBP_dh; C-terminal binding protein (CtBP), D-isomer-specific 2-hydroxyacid dehydrogenases related repressor
    3. NM_001290215.2NP_001277144.1  C-terminal-binding protein 2 isoform 1

      See identical proteins and their annotated locations for NP_001277144.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (5) contains a distinct 5' UTR and 5' CDS, compared to variant 2. Variants 1, 3, 4, and 5-8 all encode the same isoform (1), which has a distinct N-terminus that is 540 aa shorter than the N-terminus of isoform 2. The protein is thought to bind to the C-terminus of the adenovirus E1A proteins. Studies in mice suggest that this protein is involved in transcriptional repression.
      Source sequence(s)
      AK290390, AL731571, HY147073
      Consensus CDS
      CCDS7643.1
      UniProtKB/Swiss-Prot
      P56545
      Related
      ENSP00000434630.1, OTTHUMP00000235908, ENST00000531469.5, OTTHUMT00000050902
      Conserved Domains (1) summary
      cd05299
      Location:34352
      CtBP_dh; C-terminal binding protein (CtBP), D-isomer-specific 2-hydroxyacid dehydrogenases related repressor
    4. NM_001321012.1NP_001307941.1  C-terminal-binding protein 2 isoform 1

      Status: REVIEWED

      Source sequence(s)
      AL731571, BE671217, CX165167, DB200827, HY096630
      Consensus CDS
      CCDS7643.1
      UniProtKB/Swiss-Prot
      P56545
      Conserved Domains (1) summary
      cd05299
      Location:34352
      CtBP_dh; C-terminal binding protein (CtBP), D-isomer-specific 2-hydroxyacid dehydrogenases related repressor
    5. NM_001321013.1NP_001307942.1  C-terminal-binding protein 2 isoform 1

      Status: REVIEWED

      Source sequence(s)
      AL731571, BE671217, BM800106, HY046871, HY147073
      Consensus CDS
      CCDS7643.1
      UniProtKB/Swiss-Prot
      P56545
      Conserved Domains (1) summary
      cd05299
      Location:34352
      CtBP_dh; C-terminal binding protein (CtBP), D-isomer-specific 2-hydroxyacid dehydrogenases related repressor
    6. NM_001321014.1NP_001307943.1  C-terminal-binding protein 2 isoform 1

      Status: REVIEWED

      Source sequence(s)
      AL731571, BE671217, CV029885, DB197732, HY048696, HY147073
      Consensus CDS
      CCDS7643.1
      UniProtKB/Swiss-Prot
      P56545
      Conserved Domains (1) summary
      cd05299
      Location:34352
      CtBP_dh; C-terminal binding protein (CtBP), D-isomer-specific 2-hydroxyacid dehydrogenases related repressor
    7. NM_001329.3NP_001320.1  C-terminal-binding protein 2 isoform 1

      See identical proteins and their annotated locations for NP_001320.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (1) contains a distinct 5' UTR and 5' CDS, compared to variant 2. Variants 1, 3, 4, and 5-8 all encode the same isoform (1), which has a distinct N-terminus that is 540 aa shorter than the N-terminus of isoform 2. The protein is thought to bind to the C-terminus of the adenovirus E1A proteins. Studies in mice suggest that this protein is involved in transcriptional repression.
      Source sequence(s)
      AL731571, AL833398, BM712328
      Consensus CDS
      CCDS7643.1
      UniProtKB/Swiss-Prot
      P56545
      Related
      ENSP00000338615.5, OTTHUMP00000020699, ENST00000337195.9, OTTHUMT00000050900
      Conserved Domains (1) summary
      cd05299
      Location:34352
      CtBP_dh; C-terminal binding protein (CtBP), D-isomer-specific 2-hydroxyacid dehydrogenases related repressor
    8. NM_001363508.1NP_001350437.1  C-terminal-binding protein 2 isoform 3

      Status: REVIEWED

      Source sequence(s)
      AL731571
      Consensus CDS
      CCDS86154.1
      Conserved Domains (1) summary
      cd05299
      Location:102420
      CtBP_dh; C-terminal binding protein (CtBP), D-isomer-specific 2-hydroxyacid dehydrogenases related repressor
    9. NM_022802.2NP_073713.2  C-terminal-binding protein 2 isoform 2

      See identical proteins and their annotated locations for NP_073713.2

      Status: REVIEWED

      Description
      Transcript Variant: This variant (2) represents the longest transcript and encodes the longer isoform (2). This protein localizes to synaptic ribbons, synapses used for fast tonic neurotransmitter release in a subset of specialized neurons.
      Source sequence(s)
      AF222711, AL731571, AL833398
      Consensus CDS
      CCDS7644.1
      UniProtKB/Swiss-Prot
      P56545
      Related
      ENSP00000311825.6, OTTHUMP00000020701, ENST00000309035.10, OTTHUMT00000050905
      Conserved Domains (2) summary
      COG0111
      Location:590900
      SerA; Phosphoglycerate dehydrogenase or related dehydrogenase [Coenzyme transport and metabolism, General function prediction only]
      cd05299
      Location:574892
      CtBP_dh; C-terminal binding protein (CtBP), D-isomer-specific 2-hydroxyacid dehydrogenases related repressor

    RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p12 Primary Assembly

    Genomic

    1. NC_000010.11 Reference GRCh38.p12 Primary Assembly

      Range
      124987849..125161061 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005269572.4XP_005269629.1  C-terminal-binding protein 2 isoform X2

      See identical proteins and their annotated locations for XP_005269629.1

      UniProtKB/Swiss-Prot
      P56545
      Conserved Domains (1) summary
      cd05299
      Location:34352
      CtBP_dh; C-terminal binding protein (CtBP), D-isomer-specific 2-hydroxyacid dehydrogenases related repressor
    2. XM_005269568.5XP_005269625.1  C-terminal-binding protein 2 isoform X2

      See identical proteins and their annotated locations for XP_005269625.1

      UniProtKB/Swiss-Prot
      P56545
      Conserved Domains (1) summary
      cd05299
      Location:34352
      CtBP_dh; C-terminal binding protein (CtBP), D-isomer-specific 2-hydroxyacid dehydrogenases related repressor
    3. XM_005269569.3XP_005269626.1  C-terminal-binding protein 2 isoform X2

      See identical proteins and their annotated locations for XP_005269626.1

      UniProtKB/Swiss-Prot
      P56545
      Conserved Domains (1) summary
      cd05299
      Location:34352
      CtBP_dh; C-terminal binding protein (CtBP), D-isomer-specific 2-hydroxyacid dehydrogenases related repressor
    4. XM_011539357.2XP_011537659.1  C-terminal-binding protein 2 isoform X3

      See identical proteins and their annotated locations for XP_011537659.1

      Conserved Domains (1) summary
      cd05299
      Location:9327
      CtBP_dh; C-terminal binding protein (CtBP), D-isomer-specific 2-hydroxyacid dehydrogenases related repressor
    5. XM_005269561.3XP_005269618.1  C-terminal-binding protein 2 isoform X2

      See identical proteins and their annotated locations for XP_005269618.1

      UniProtKB/Swiss-Prot
      P56545
      Conserved Domains (1) summary
      cd05299
      Location:34352
      CtBP_dh; C-terminal binding protein (CtBP), D-isomer-specific 2-hydroxyacid dehydrogenases related repressor
    6. XM_011539353.2XP_011537655.1  C-terminal-binding protein 2 isoform X2

      See identical proteins and their annotated locations for XP_011537655.1

      UniProtKB/Swiss-Prot
      P56545
      Conserved Domains (1) summary
      cd05299
      Location:34352
      CtBP_dh; C-terminal binding protein (CtBP), D-isomer-specific 2-hydroxyacid dehydrogenases related repressor
    7. XM_006717642.3XP_006717705.1  C-terminal-binding protein 2 isoform X2

      See identical proteins and their annotated locations for XP_006717705.1

      UniProtKB/Swiss-Prot
      P56545
      Conserved Domains (1) summary
      cd05299
      Location:34352
      CtBP_dh; C-terminal binding protein (CtBP), D-isomer-specific 2-hydroxyacid dehydrogenases related repressor
    8. XM_011539351.2XP_011537653.1  C-terminal-binding protein 2 isoform X2

      See identical proteins and their annotated locations for XP_011537653.1

      UniProtKB/Swiss-Prot
      P56545
      Conserved Domains (1) summary
      cd05299
      Location:34352
      CtBP_dh; C-terminal binding protein (CtBP), D-isomer-specific 2-hydroxyacid dehydrogenases related repressor
    9. XM_011539354.2XP_011537656.1  C-terminal-binding protein 2 isoform X2

      See identical proteins and their annotated locations for XP_011537656.1

      UniProtKB/Swiss-Prot
      P56545
      Conserved Domains (1) summary
      cd05299
      Location:34352
      CtBP_dh; C-terminal binding protein (CtBP), D-isomer-specific 2-hydroxyacid dehydrogenases related repressor
    10. XM_024447831.1XP_024303599.1  C-terminal-binding protein 2 isoform X3

      Conserved Domains (1) summary
      cd05299
      Location:9327
      CtBP_dh; C-terminal binding protein (CtBP), D-isomer-specific 2-hydroxyacid dehydrogenases related repressor
    11. XM_017015756.2XP_016871245.1  C-terminal-binding protein 2 isoform X2

      UniProtKB/Swiss-Prot
      P56545
      Conserved Domains (1) summary
      cd05299
      Location:34352
      CtBP_dh; C-terminal binding protein (CtBP), D-isomer-specific 2-hydroxyacid dehydrogenases related repressor
    12. XM_024447830.1XP_024303598.1  C-terminal-binding protein 2 isoform X2

      Conserved Domains (1) summary
      cd05299
      Location:34352
      CtBP_dh; C-terminal binding protein (CtBP), D-isomer-specific 2-hydroxyacid dehydrogenases related repressor
    13. XM_005269571.3XP_005269628.1  C-terminal-binding protein 2 isoform X2

      See identical proteins and their annotated locations for XP_005269628.1

      UniProtKB/Swiss-Prot
      P56545
      Conserved Domains (1) summary
      cd05299
      Location:34352
      CtBP_dh; C-terminal binding protein (CtBP), D-isomer-specific 2-hydroxyacid dehydrogenases related repressor
    14. XM_005269564.3XP_005269621.1  C-terminal-binding protein 2 isoform X2

      See identical proteins and their annotated locations for XP_005269621.1

      UniProtKB/Swiss-Prot
      P56545
      Conserved Domains (1) summary
      cd05299
      Location:34352
      CtBP_dh; C-terminal binding protein (CtBP), D-isomer-specific 2-hydroxyacid dehydrogenases related repressor
    15. XM_011539358.2XP_011537660.1  C-terminal-binding protein 2 isoform X3

      See identical proteins and their annotated locations for XP_011537660.1

      Conserved Domains (1) summary
      cd05299
      Location:9327
      CtBP_dh; C-terminal binding protein (CtBP), D-isomer-specific 2-hydroxyacid dehydrogenases related repressor
    16. XM_005269567.3XP_005269624.1  C-terminal-binding protein 2 isoform X2

      See identical proteins and their annotated locations for XP_005269624.1

      UniProtKB/Swiss-Prot
      P56545
      Conserved Domains (1) summary
      cd05299
      Location:34352
      CtBP_dh; C-terminal binding protein (CtBP), D-isomer-specific 2-hydroxyacid dehydrogenases related repressor
    17. XM_011539355.2XP_011537657.1  C-terminal-binding protein 2 isoform X2

      See identical proteins and their annotated locations for XP_011537657.1

      UniProtKB/Swiss-Prot
      P56545
      Conserved Domains (1) summary
      cd05299
      Location:34352
      CtBP_dh; C-terminal binding protein (CtBP), D-isomer-specific 2-hydroxyacid dehydrogenases related repressor
    18. XM_017015757.2XP_016871246.1  C-terminal-binding protein 2 isoform X2

      UniProtKB/Swiss-Prot
      P56545
      Conserved Domains (1) summary
      cd05299
      Location:34352
      CtBP_dh; C-terminal binding protein (CtBP), D-isomer-specific 2-hydroxyacid dehydrogenases related repressor
    19. XM_011539349.3XP_011537651.1  C-terminal-binding protein 2 isoform X1

      UniProtKB/TrEMBL
      Q5SQP8
      Related
      ENSP00000357816.5, OTTHUMP00000020700, ENST00000334808.10
      Conserved Domains (1) summary
      cd05299
      Location:102420
      CtBP_dh; C-terminal binding protein (CtBP), D-isomer-specific 2-hydroxyacid dehydrogenases related repressor
    Support Center