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    GGT3P gamma-glutamyltransferase 3 pseudogene [ Homo sapiens (human) ]

    Gene ID: 2679, updated on 4-Feb-2018
    Official Symbol
    GGT3Pprovided by HGNC
    Official Full Name
    gamma-glutamyltransferase 3 pseudogeneprovided by HGNC
    Primary source
    HGNC:HGNC:4252
    See related
    Ensembl:ENSG00000197421
    Gene type
    pseudo
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    GGT3
    Expression
    Biased expression in kidney (RPKM 10.5), small intestine (RPKM 4.5) and 12 other tissues See more
    Location:
    22q11.21
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    108 current GRCh38.p7 (GCF_000001405.33) 22 NC_000022.11 (18773689..18791961, complement)
    105 previous assembly GRCh37.p13 (GCF_000001405.25) 22 NC_000022.10 (18761202..18779474, complement)

    Chromosome 22 - NC_000022.11Genomic Context describing neighboring genes Neighboring gene long intergenic non-protein coding RNA 1662 Neighboring gene uncharacterized LOC105377182 Neighboring gene E2F transcription factor 6 pseudogene 1 Neighboring gene putative POM121-like protein 1

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Jun 15 11:32:44 2016

    Related articles in PubMed

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    • Aflatoxin activation and detoxification, organism-specific biosystem (from REACTOME)
      Aflatoxin activation and detoxification, organism-specific biosystemAflatoxins are among the principal mycotoxins produced as secondary metabolites by the molds Aspergillus flavus and Aspergillus parasiticus that contaminate economically important food and feed crops...
    • Biological oxidations, organism-specific biosystem (from REACTOME)
      Biological oxidations, organism-specific biosystemAll organisms are constantly exposed to foreign chemicals every day. These can be man-made (drugs, industrial chemicals) or natural (alkaloids, toxins from plants and animals). Uptake is usually via ...
    • Glutathione conjugation, organism-specific biosystem (from REACTOME)
      Glutathione conjugation, organism-specific biosystemGlutathione S-Transferases (GSTs; EC 2.5.1.18) are another major set of phase II conjugation enzymes. They can be found in the cytosol as well as being microsomal membrane-bound. Cytosolic GSTs are e...
    • Glutathione synthesis and recycling, organism-specific biosystem (from REACTOME)
      Glutathione synthesis and recycling, organism-specific biosystemThe combination of glutamate, cysteine and ATP is required to form glutathione. The steps involved in the synthesis and recycling of glutathione are outlined (Meister, 1988).
    • Metabolism, organism-specific biosystem (from REACTOME)
      Metabolism, organism-specific biosystemMetabolic processes in human cells generate energy through the oxidation of molecules consumed in the diet and mediate the synthesis of diverse essential molecules not taken in the diet as well as th...
    • Phase II conjugation, organism-specific biosystem (from REACTOME)
      Phase II conjugation, organism-specific biosystemPhase II of biotransformation is concerned with conjugation, that is using groups from cofactors to react with functional groups present or introduced from phase I on the compound. The enzymes involv...

    Markers

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    glutathione hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    hypoglycin A gamma-glutamyl transpeptidase activity IEA
    Inferred from Electronic Annotation
    more info
     
    leukotriene C4 gamma-glutamyl transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    biological_process ND
    No biological Data available
    more info
     
    glutathione biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
     
    glutathione catabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    leukotriene D4 biosynthetic process ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    proteolysis IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    extracellular exosome HDA PubMed 
    integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_003267.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC008132
      Related
      ENST00000453783.1

    RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 108

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p7 Primary Assembly

    Genomic

    1. NC_000022.11 Reference GRCh38.p7 Primary Assembly

      Range
      18773689..18791961 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate CHM1_1.1

    Genomic

    1. NC_018933.2 Alternate CHM1_1.1

      Range
      18760885..18779155 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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