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    cbl Cbl proto-oncogene, E3 ubiquitin protein ligase [ Xenopus tropicalis (tropical clawed frog) ]

    Gene ID: 594900, updated on 20-Jun-2018

    Summary

    Symbol
    cblprovided by Xenbase
    Full Name
    Cbl proto-oncogene, E3 ubiquitin protein ligaseprovided by Xenbase
    Primary source
    Xenbase:XB-GENE-6258452
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Xenopus tropicalis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
    Also known as
    c-cbl; rnf55
    Orthologs

    Genomic context

    See cbl in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    103 current Xenopus_tropicalis_v9.1 (GCF_000004195.3) 7 NC_030683.1 (85873101..85927739)
    102 previous assembly Xtropicalis_v7 (GCF_000004195.2) Unplaced Scaffold NW_004668240.1 (69859851..69914449, complement)

    Chromosome 7 - NC_030683.1Genomic Context describing neighboring genes Neighboring gene PDZ domain containing 3 Neighboring gene coiled-coil domain containing 153 Neighboring gene melanoma cell adhesion molecule Neighboring gene ring finger protein 26

    Genomic regions, transcripts, and products

    Pathways from BioSystems

    General gene information

    Homology

    General protein information

    Preferred Names
    E3 ubiquitin-protein ligase CBL
    Names
    Cas-Br-M (murine) ecotropic retroviral transforming sequence
    NP_001122110.1
    XP_012822121.1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001128638.1NP_001122110.1  E3 ubiquitin-protein ligase CBL

      See identical proteins and their annotated locations for NP_001122110.1

      Status: PROVISIONAL

      Source sequence(s)
      BC167455
      UniProtKB/TrEMBL
      B3DLI0
      Conserved Domains (5) summary
      cd09920
      Location:238334
      SH2_Cbl-b_TKB; Src homology 2 (SH2) domain found in the Cbl-b TKB domain
      cd14393
      Location:839878
      UBA_c-Cbl; UBA domain found in E3 ubiquitin-protein ligase Cbl and similar proteins
      pfam00097
      Location:363401
      zf-C3HC4; Zinc finger, C3HC4 type (RING finger)
      pfam02262
      Location:36157
      Cbl_N; CBL proto-oncogene N-terminal domain 1
      pfam02761
      Location:161244
      Cbl_N2; CBL proto-oncogene N-terminus, EF hand-like domain

    RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Xenopus_tropicalis_v9.1 Primary Assembly

    Genomic

    1. NC_030683.1 Reference Xenopus_tropicalis_v9.1 Primary Assembly

      Range
      85873101..85927739
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_012966667.2XP_012822121.1  E3 ubiquitin-protein ligase CBL isoform X1

      Conserved Domains (5) summary
      cd09920
      Location:304400
      SH2_Cbl-b_TKB; Src homology 2 (SH2) domain found in the Cbl-b TKB domain
      cd14393
      Location:855894
      UBA_c-Cbl; UBA domain found in E3 ubiquitin-protein ligase Cbl and similar proteins
      pfam00097
      Location:429467
      zf-C3HC4; Zinc finger, C3HC4 type (RING finger)
      pfam02262
      Location:102223
      Cbl_N; CBL proto-oncogene N-terminal domain 1
      pfam02761
      Location:227310
      Cbl_N2; CBL proto-oncogene N-terminus, EF hand-like domain
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