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    CRK CRK proto-oncogene, adaptor protein [ Bos taurus (cattle) ]

    Gene ID: 512841, updated on 27-Aug-2018

    Summary

    Official Symbol
    CRKprovided by VGNC
    Official Full Name
    CRK proto-oncogene, adaptor proteinprovided by VGNC
    Primary source
    VGNC:VGNC:27716
    See related
    BGD:BT22541; Ensembl:ENSBTAG00000005665
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs

    Genomic context

    See CRK in Genome Data Viewer
    Location:
    chromosome: 19
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    106 current ARS-UCD1.2 (GCF_002263795.1) 19 NC_037346.1 (22566859..22586885, complement)
    105 previous assembly Bos_taurus_UMD_3.1.1 (GCF_000003055.6) 19 AC_000176.1 (23139102..23159121, complement)

    Chromosome 19 - NC_037346.1Genomic Context describing neighboring genes Neighboring gene double C2 domain beta Neighboring gene uncharacterized LOC112442619 Neighboring gene tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon Neighboring gene transfer RNA glutamic acid (anticodon UUC) Neighboring gene geranylgeranyl transferase type-2 subunit beta-like Neighboring gene myosin IC

    Genomic regions, transcripts, and products

    Pathways from BioSystems

    General gene information

    Markers

    Homology

    General protein information

    Preferred Names
    adapter molecule crk
    Names
    v-crk sarcoma virus CT10 oncogene homolog

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001192334.1NP_001179263.1  adapter molecule crk

      See identical proteins and their annotated locations for NP_001179263.1

      Status: PROVISIONAL

      Source sequence(s)
      NKLS02000019
      UniProtKB/TrEMBL
      E1BQ32
      Related
      ENSBTAP00000007443.5, ENSBTAT00000007443.5
      Conserved Domains (3) summary
      cd09926
      Location:5122
      SH2_CRK_like; Src homology 2 domain found in cancer-related signaling adaptor protein CRK
      cd11758
      Location:135189
      SH3_CRK_N; N-terminal Src Homology 3 domain of Ct10 Regulator of Kinase adaptor proteins
      cd11759
      Location:237293
      SH3_CRK_C; C-terminal Src Homology 3 domain of Ct10 Regulator of Kinase adaptor proteins

    RefSeqs of Annotated Genomes: Bos taurus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD1.2 Primary Assembly

    Genomic

    1. NC_037346.1 Reference ARS-UCD1.2 Primary Assembly

      Range
      22566859..22586885 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005220095.3XP_005220152.2  adapter molecule crk isoform X1

      See identical proteins and their annotated locations for XP_005220152.2

      Conserved Domains (2) summary
      cd09926
      Location:5122
      SH2_CRK_like; Src homology 2 domain found in cancer-related signaling adaptor protein CRK
      cd11758
      Location:135189
      SH3_CRK_N; N-terminal Src Homology 3 domain of Ct10 Regulator of Kinase adaptor proteins
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