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    Dtx3 deltex E3 ubiquitin ligase 3 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 500847, updated on 12-Aug-2018

    Summary

    Official Symbol
    Dtx3provided by RGD
    Official Full Name
    deltex E3 ubiquitin ligase 3provided by RGD
    Primary source
    RGD:1566181
    See related
    Ensembl:ENSRNOG00000005129
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1566181
    Expression
    Biased expression in Brain (RPKM 134.5), Kidney (RPKM 60.5) and 9 other tissues See more
    Orthologs

    Genomic context

    See Dtx3 in Genome Data Viewer
    Location:
    7q22
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    106 current Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (70476737..70482852, complement)
    104 previous assembly Rnor_5.0 (GCF_000001895.4) 7 NC_005106.3 (70654378..70660222, complement)

    Chromosome 7 - NC_005106.4Genomic Context describing neighboring genes Neighboring gene beta-1,4-N-acetyl-galactosaminyl transferase 1 Neighboring gene solute carrier family 26, member 10 Neighboring gene Rho guanine nucleotide exchange factor 25 Neighboring gene phosphatidylinositol-5-phosphate 4-kinase type 2 gamma Neighboring gene kinesin family member 5A

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Pathways from BioSystems

    • Notch Signaling Pathway, organism-specific biosystem (from WikiPathways)
      Notch Signaling Pathway, organism-specific biosystemThe Notch signaling pathway is an evolutionarily conserved, intercellular signaling mechanism essential for proper embryonic development in all metazoan organisms in the Animal kingdom. The Notch pro...
    • Notch signaling pathway, organism-specific biosystem (from KEGG)
      Notch signaling pathway, organism-specific biosystemThe Notch signaling pathway is an evolutionarily conserved, intercellular signaling mechanism essential for proper embryonic development in all metazoan organisms in the Animal kingdom. The Notch pro...
    • Notch signaling pathway, conserved biosystem (from KEGG)
      Notch signaling pathway, conserved biosystemThe Notch signaling pathway is an evolutionarily conserved, intercellular signaling mechanism essential for proper embryonic development in all metazoan organisms in the Animal kingdom. The Notch pro...

    General gene information

    Markers

    Homology

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    Notch signaling pathway IEA
    Inferred from Electronic Annotation
    more info
     
    Notch signaling pathway ISO
    Inferred from Sequence Orthology
    more info
     
    protein ubiquitination IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    probable E3 ubiquitin-protein ligase DTX3
    Names
    deltex 3 homolog
    deltex 3, E3 ubiquitin ligase
    deltex homolog 3
    protein deltex-3
    NP_001178918.1
    XP_006241554.1
    XP_006241555.1
    XP_006241556.1
    XP_006241557.1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001191989.1NP_001178918.1  probable E3 ubiquitin-protein ligase DTX3

      See identical proteins and their annotated locations for NP_001178918.1

      Status: PROVISIONAL

      Source sequence(s)
      AC114111
      UniProtKB/TrEMBL
      F1LY78
      Related
      ENSRNOP00000006815.4, ENSRNOT00000006815.4
      Conserved Domains (2) summary
      cd09633
      Location:211343
      Deltex_C; Domain found at the C-terminus of deltex-like
      cd00162
      Location:163202
      RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...

    RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Rnor_6.0 Primary Assembly

    Genomic

    1. NC_005106.4 Reference Rnor_6.0 Primary Assembly

      Range
      70476737..70482852 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006241493.3XP_006241555.1  probable E3 ubiquitin-protein ligase DTX3 isoform X1

      See identical proteins and their annotated locations for XP_006241555.1

      Conserved Domains (2) summary
      cd09633
      Location:214325
      Deltex_C; Domain found at the C-terminus of deltex-like
      cd00162
      Location:166205
      RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
    2. XM_006241492.3XP_006241554.1  probable E3 ubiquitin-protein ligase DTX3 isoform X1

      See identical proteins and their annotated locations for XP_006241554.1

      Conserved Domains (2) summary
      cd09633
      Location:214325
      Deltex_C; Domain found at the C-terminus of deltex-like
      cd00162
      Location:166205
      RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
    3. XM_006241494.3XP_006241556.1  probable E3 ubiquitin-protein ligase DTX3 isoform X2

      Conserved Domains (2) summary
      cd09633
      Location:211322
      Deltex_C; Domain found at the C-terminus of deltex-like
      cd00162
      Location:163202
      RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
    4. XM_006241495.3XP_006241557.1  probable E3 ubiquitin-protein ligase DTX3 isoform X3

      See identical proteins and their annotated locations for XP_006241557.1

      Conserved Domains (2) summary
      cd09633
      Location:214346
      Deltex_C; Domain found at the C-terminus of deltex-like
      cd00162
      Location:166205
      RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...

    Alternate Rn_Celera

    Genomic

    1. AC_000075.1 Alternate Rn_Celera

      Range
      60155333..60160117 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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