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    LMO7 LIM domain 7 [ Pan troglodytes (chimpanzee) ]

    Gene ID: 452604, updated on 5-Oct-2018

    Summary

    Official Symbol
    LMO7provided by VGNC
    Official Full Name
    LIM domain 7provided by VGNC
    Primary source
    VGNC:VGNC:13124
    Locus tag
    CK820_G0004552
    See related
    Ensembl:ENSPTRG00000005935
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Pan troglodytes
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
    Also known as
    UCHL3

    Genomic context

    See LMO7 in Genome Data Viewer
    Location:
    chromosome: 13
    Exon count:
    50
    Annotation release Status Assembly Chr Location
    105 current Clint_PTRv2 (GCF_002880755.1) 13 NC_036892.1 (56797423..57108135)
    103 previous assembly Pan_troglodytes-2.1.4 (GCF_000001515.6) 13 NC_006480.3 (75470143..75787041)

    Chromosome 13 - NC_036892.1Genomic Context describing neighboring genes Neighboring gene TBC1 domain family member 4 Neighboring gene COMM domain containing 6 Neighboring gene basic proline-rich protein-like Neighboring gene uncharacterized LOC107967928 Neighboring gene LMO7 downstream neighbor

    Genomic regions, transcripts, and products

    Expression

    • Project title: Tissue-specific RNA-sequencing for ten non-human primate species
    • Description: Total RNA sequencing of fifteen different tissues for ten non-human primates
    • BioProject: PRJNA271912
    • Publication: PMID 25392405
    • Analysis date: Tue Apr 3 07:13:10 2018

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Pathways from BioSystems

    • Adherens junction, organism-specific biosystem (from KEGG)
      Adherens junction, organism-specific biosystemCell-cell adherens junctions (AJs), the most common type of intercellular adhesions, are important for maintaining tissue architecture and cell polarity and can limit cell movement and proliferation....
    • Adherens junction, conserved biosystem (from KEGG)
      Adherens junction, conserved biosystemCell-cell adherens junctions (AJs), the most common type of intercellular adhesions, are important for maintaining tissue architecture and cell polarity and can limit cell movement and proliferation....

    General gene information

    Markers

    Homology

    • Homologs of the LMO7 gene: The LMO7 gene is conserved in human, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, and frog.

    General protein information

    Preferred Names
    LIM domain only protein 7; ubiquitin carboxyl-terminal hydrolase isozyme L3
    Names
    ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)
    XP_001139492.1
    XP_016780866.1
    XP_016780867.1
    XP_016780868.1
    XP_016780869.1
    XP_016780870.1
    XP_016780871.1
    XP_016780872.1
    XP_016780873.1
    XP_016780874.1
    XP_016780875.1
    XP_016780876.1
    XP_016780877.1
    XP_016780878.1
    XP_016780879.1
    XP_016780880.1
    XP_016780882.1
    XP_016780883.1
    XP_016780884.1
    XP_016780885.1
    XP_016780886.1
    XP_016780887.1
    XP_016780888.1
    XP_016780889.1
    XP_016780890.1
    XP_016780892.1
    XP_016780893.1
    XP_016780894.1
    XP_024204051.1
    XP_024204052.1
    XP_024204053.1

    NCBI Reference Sequences (RefSeq)

    RefSeqs of Annotated Genomes: Pan troglodytes Annotation Release 105 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Clint_PTRv2 Primary Assembly

    Genomic

    1. NC_036892.1 Reference Clint_PTRv2 Primary Assembly

      Range
      56797423..57108135
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_016925377.1XP_016780866.1  LIM domain only protein 7 isoform X1

    2. XM_016925378.1XP_016780867.1  LIM domain only protein 7 isoform X2

    3. XM_016925379.1XP_016780868.1  LIM domain only protein 7 isoform X3

      Conserved Domains (7) summary
      cd09616
      Location:6158
      Peptidase_C12_UCH_L1_L3; Cysteine peptidase C12 containing ubiquitin carboxyl-terminal hydrolase (UCH) families L1 and L3
      cd00014
      Location:209316
      CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
      cd00136
      Location:12581325
      PDZ; PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated. ...
      cd08368
      Location:18441902
      LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
      pfam15949
      Location:843989
      DUF4757; Domain of unknown function (DUF4757)
      cd16269
      Location:15001511
      GBP_C; coiled coil [structural motif]
      cl20817
      Location:14571513
      GBP_C; Guanylate-binding protein, C-terminal domain
    4. XM_016925380.1XP_016780869.1  LIM domain only protein 7 isoform X4

    5. XM_016925382.1XP_016780871.1  LIM domain only protein 7 isoform X6

      Conserved Domains (7) summary
      cd09616
      Location:6158
      Peptidase_C12_UCH_L1_L3; Cysteine peptidase C12 containing ubiquitin carboxyl-terminal hydrolase (UCH) families L1 and L3
      cd00014
      Location:209316
      CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
      cd00136
      Location:12581325
      PDZ; PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated. ...
      cd08368
      Location:18251883
      LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
      pfam15949
      Location:843989
      DUF4757; Domain of unknown function (DUF4757)
      cd16269
      Location:14811492
      GBP_C; coiled coil [structural motif]
      cl20817
      Location:14381494
      GBP_C; Guanylate-binding protein, C-terminal domain
    6. XM_016925381.1XP_016780870.1  LIM domain only protein 7 isoform X5

    7. XM_016925384.1XP_016780873.1  LIM domain only protein 7 isoform X8

      Conserved Domains (7) summary
      cd09616
      Location:6158
      Peptidase_C12_UCH_L1_L3; Cysteine peptidase C12 containing ubiquitin carboxyl-terminal hydrolase (UCH) families L1 and L3
      cd00014
      Location:209316
      CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
      cd00136
      Location:12581325
      PDZ; PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated. ...
      cd08368
      Location:18171875
      LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
      pfam15949
      Location:843989
      DUF4757; Domain of unknown function (DUF4757)
      cd16269
      Location:14731484
      GBP_C; coiled coil [structural motif]
      cl20817
      Location:14301486
      GBP_C; Guanylate-binding protein, C-terminal domain
    8. XM_016925385.1XP_016780874.1  LIM domain only protein 7 isoform X9

      Conserved Domains (7) summary
      cd09616
      Location:6158
      Peptidase_C12_UCH_L1_L3; Cysteine peptidase C12 containing ubiquitin carboxyl-terminal hydrolase (UCH) families L1 and L3
      cd00014
      Location:209316
      CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
      cd00136
      Location:12581325
      PDZ; PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated. ...
      cd08368
      Location:17981856
      LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
      pfam15949
      Location:843989
      DUF4757; Domain of unknown function (DUF4757)
      cd16269
      Location:14541465
      GBP_C; coiled coil [structural motif]
      cl20817
      Location:14111467
      GBP_C; Guanylate-binding protein, C-terminal domain
    9. XM_016925386.1XP_016780875.1  LIM domain only protein 7 isoform X10

    10. XM_024348283.1XP_024204051.1  LIM domain only protein 7 isoform X11

      Conserved Domains (8) summary
      cd09616
      Location:6158
      Peptidase_C12_UCH_L1_L3; Cysteine peptidase C12 containing ubiquitin carboxyl-terminal hydrolase (UCH) families L1 and L3
      cd00014
      Location:209316
      CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
      cd00136
      Location:11901257
      PDZ; PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated. ...
      cd08368
      Location:17491807
      LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
      cd16269
      Location:14051416
      GBP_C; coiled coil [structural motif]
      pfam15949
      Location:775922
      DUF4757; Domain of unknown function (DUF4757)
      cl20817
      Location:13621418
      GBP_C; Guanylate-binding protein, C-terminal domain
      cl26511
      Location:13631521
      Neuromodulin_N; Gap junction protein N-terminal region
    11. XM_016925387.1XP_016780876.1  LIM domain only protein 7 isoform X12

      Conserved Domains (6) summary
      cd09616
      Location:6158
      Peptidase_C12_UCH_L1_L3; Cysteine peptidase C12 containing ubiquitin carboxyl-terminal hydrolase (UCH) families L1 and L3
      cd00014
      Location:209316
      CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
      cd00136
      Location:11901257
      PDZ; PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated. ...
      pfam15949
      Location:775921
      DUF4757; Domain of unknown function (DUF4757)
      cd16269
      Location:14051416
      GBP_C; coiled coil [structural motif]
      cl20817
      Location:13621418
      GBP_C; Guanylate-binding protein, C-terminal domain
    12. XM_016925388.1XP_016780877.1  LIM domain only protein 7 isoform X13

    13. XM_016925390.1XP_016780879.1  LIM domain only protein 7 isoform X15

      Conserved Domains (7) summary
      cd09616
      Location:6158
      Peptidase_C12_UCH_L1_L3; Cysteine peptidase C12 containing ubiquitin carboxyl-terminal hydrolase (UCH) families L1 and L3
      cd00014
      Location:209316
      CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
      cd00136
      Location:10961163
      PDZ; PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated. ...
      cd08368
      Location:16551713
      LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
      pfam15949
      Location:681827
      DUF4757; Domain of unknown function (DUF4757)
      cd16269
      Location:13111322
      GBP_C; coiled coil [structural motif]
      cl20817
      Location:12681324
      GBP_C; Guanylate-binding protein, C-terminal domain
    14. XM_016925396.1XP_016780885.1  LIM domain only protein 7 isoform X21

    15. XM_016925404.1XP_016780893.1  LIM domain only protein 7 isoform X23

      Conserved Domains (7) summary
      cd09616
      Location:6158
      Peptidase_C12_UCH_L1_L3; Cysteine peptidase C12 containing ubiquitin carboxyl-terminal hydrolase (UCH) families L1 and L3
      cd00014
      Location:209316
      CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
      cd00136
      Location:856923
      PDZ; PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated. ...
      cd08368
      Location:14151473
      LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
      pfam15949
      Location:429587
      DUF4757; Domain of unknown function (DUF4757)
      cd16269
      Location:10711082
      GBP_C; coiled coil [structural motif]
      cl20817
      Location:10281084
      GBP_C; Guanylate-binding protein, C-terminal domain
    16. XM_016925397.1XP_016780886.1  LIM domain only protein 7 isoform X22

    17. XM_016925394.1XP_016780883.1  LIM domain only protein 7 isoform X19

    18. XM_016925405.1XP_016780894.1  ubiquitin carboxyl-terminal hydrolase isozyme L3 isoform X26

      UniProtKB/TrEMBL
      K7CD22
      Related
      ENSPTRP00000053459.3, ENSPTRT00000060146.3
      Conserved Domains (1) summary
      cd09616
      Location:6227
      Peptidase_C12_UCH_L1_L3; Cysteine peptidase C12 containing ubiquitin carboxyl-terminal hydrolase (UCH) families L1 and L3
    19. XM_016925383.1XP_016780872.1  LIM domain only protein 7 isoform X7

    20. XM_001139492.3XP_001139492.1  LIM domain only protein 7 isoform X25

      See identical proteins and their annotated locations for XP_001139492.1

      UniProtKB/TrEMBL
      H2Q7N3
      Related
      ENSPTRP00000091512.1, ENSPTRT00000087011.1
      Conserved Domains (7) summary
      cd00014
      Location:74181
      CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
      cd00136
      Location:721788
      PDZ; PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated. ...
      cd08368
      Location:12801338
      LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
      cd16269
      Location:936947
      GBP_C; coiled coil [structural motif]
      pfam15949
      Location:294453
      DUF4757; Domain of unknown function (DUF4757)
      cl20817
      Location:893949
      GBP_C; Guanylate-binding protein, C-terminal domain
      cl26511
      Location:8941052
      Neuromodulin_N; Gap junction protein N-terminal region
    21. XM_016925395.2XP_016780884.1  LIM domain only protein 7 isoform X20

      Related
      ENSPTRP00000074339.1
      Conserved Domains (7) summary
      cd00014
      Location:17129
      CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
      cd00136
      Location:10031070
      PDZ; PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated. ...
      cd08368
      Location:15621620
      LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
      cd16269
      Location:12181229
      GBP_C; coiled coil [structural motif]
      pfam15949
      Location:588735
      DUF4757; Domain of unknown function (DUF4757)
      cl20817
      Location:11751231
      GBP_C; Guanylate-binding protein, C-terminal domain
      cl26511
      Location:11761334
      Neuromodulin_N; Gap junction protein N-terminal region
    22. XM_016925400.2XP_016780889.1  LIM domain only protein 7 isoform X17

    23. XM_016925389.2XP_016780878.1  LIM domain only protein 7 isoform X14

    24. XM_024348284.1XP_024204052.1  LIM domain only protein 7 isoform X18

      Conserved Domains (7) summary
      cd00014
      Location:17129
      CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
      cd00136
      Location:10031070
      PDZ; PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated. ...
      cd08368
      Location:16031661
      LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
      cd16269
      Location:12591270
      GBP_C; coiled coil [structural motif]
      pfam15949
      Location:588735
      DUF4757; Domain of unknown function (DUF4757)
      cl20817
      Location:12161272
      GBP_C; Guanylate-binding protein, C-terminal domain
      cl26511
      Location:12171375
      Neuromodulin_N; Gap junction protein N-terminal region
    25. XM_016925393.1XP_016780882.1  LIM domain only protein 7 isoform X17

    26. XM_024348285.1XP_024204053.1  LIM domain only protein 7 isoform X24

      Conserved Domains (6) summary
      cd00136
      Location:770837
      PDZ; PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated. ...
      cd08368
      Location:13291387
      LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
      cd16269
      Location:985996
      GBP_C; coiled coil [structural motif]
      pfam15949
      Location:355502
      DUF4757; Domain of unknown function (DUF4757)
      cl20817
      Location:942998
      GBP_C; Guanylate-binding protein, C-terminal domain
      cl26511
      Location:9431101
      Neuromodulin_N; Gap junction protein N-terminal region
    27. XM_016925398.1XP_016780887.1  LIM domain only protein 7 isoform X17

    28. XM_016925399.1XP_016780888.1  LIM domain only protein 7 isoform X17

    29. XM_016925391.1XP_016780880.1  LIM domain only protein 7 isoform X16

    30. XM_016925401.2XP_016780890.1  LIM domain only protein 7 isoform X17

    31. XM_016925403.1XP_016780892.1  LIM domain only protein 7 isoform X17

      Related
      ENSPTRP00000078770.1, ENSPTRT00000106544.1
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