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    POLE DNA polymerase epsilon, catalytic subunit [ Gallus gallus (chicken) ]

    Gene ID: 416997, updated on 20-Jun-2018

    Summary

    Symbol
    POLEprovided by CGNC
    Full Name
    DNA polymerase epsilon, catalytic subunitprovided by CGNC
    Primary source
    CGNC:5787
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Orthologs

    Genomic context

    See POLE in Genome Data Viewer
    Location:
    chromosome: 15
    Exon count:
    49
    Annotation release Status Assembly Chr Location
    104 current GRCg6a (GCF_000002315.5) 15 NC_006102.5 (10292860..10312570, complement)
    103 previous assembly Gallus_gallus-5.0 (GCF_000002315.4) 15 NC_006102.4 (10052470..10072135, complement)

    Chromosome 15 - NC_006102.5Genomic Context describing neighboring genes Neighboring gene phospholipase A2 group III Neighboring gene purinergic receptor P2X 2 Neighboring gene caspase recruitment domain family, member 8 Neighboring gene apoptosis inducing factor, mitochondria associated 3

    Genomic regions, transcripts, and products

    Pathways from BioSystems

    General gene information

    Homology

    General protein information

    Preferred Names
    DNA polymerase epsilon catalytic subunit A
    Names
    polymerase (DNA directed), epsilon, catalytic subunit
    polymerase (DNA) epsilon, catalytic subunit
    XP_001233985.3

    NCBI Reference Sequences (RefSeq)

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 104 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCg6a Primary Assembly

    Genomic

    1. NC_006102.5 Reference GRCg6a Primary Assembly

      Range
      10292860..10312570 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001233984.5XP_001233985.3  DNA polymerase epsilon catalytic subunit A

      Conserved Domains (5) summary
      cd05779
      Location:262465
      DNA_polB_epsilon_exo; DEDDy 3'-5' exonuclease domain of eukaryotic DNA polymerase epsilon, a family-B DNA polymerase
      cd05535
      Location:5251147
      POLBc_epsilon; DNA polymerase type-B epsilon subfamily catalytic domain. Three DNA-dependent DNA polymerases type B (alpha, delta, and epsilon) have been identified as essential for nuclear DNA replication in eukaryotes. DNA polymerase (Pol) epsilon has been proposed ...
      smart00486
      Location:261864
      POLBc; DNA polymerase type-B family
      pfam03104
      Location:80420
      DNA_pol_B_exo1; DNA polymerase family B, exonuclease domain
      pfam08490
      Location:15241921
      DUF1744; Domain of unknown function (DUF1744)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001012530.1: Suppressed sequence

      Description
      NM_001012530.1: This RefSeq was suppressed temporarily based on the calculation that the annotated protein was shorter than a protein or proteins from a putative ortholog.
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