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    SLC11A1 solute carrier family 11 member 1 [ Gallus gallus (chicken) ]

    Gene ID: 395811, updated on 12-Aug-2018

    Summary

    Symbol
    SLC11A1provided by CGNC
    Full Name
    solute carrier family 11 member 1provided by CGNC
    Primary source
    CGNC:8689
    See related
    Ensembl:ENSGALG00000011434
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Also known as
    BCG; NRAMP1
    Orthologs

    Genomic context

    See SLC11A1 in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    104 current GRCg6a (GCF_000002315.5) 7 NC_006094.5 (22547347..22552954, complement)
    103 previous assembly Gallus_gallus-5.0 (GCF_000002315.4) 7 NC_006094.4 (22673928..22679582, complement)

    Chromosome 7 - NC_006094.5Genomic Context describing neighboring genes Neighboring gene villin 1 Neighboring gene CTD small phosphatase 1 Neighboring gene ciliogenesis associated TTC17 interacting protein Neighboring gene PNKD, MBL domain containing

    Genomic regions, transcripts, and products

    Pathways from BioSystems

    • Lysosome, organism-specific biosystem (from KEGG)
      Lysosome, organism-specific biosystemLysosomes are membrane-delimited organelles in animal cells serving as the cell's main digestive compartment to which all sorts of macromolecules are delivered for degradation. They contain more than...
    • Lysosome, conserved biosystem (from KEGG)
      Lysosome, conserved biosystemLysosomes are membrane-delimited organelles in animal cells serving as the cell's main digestive compartment to which all sorts of macromolecules are delivered for degradation. They contain more than...

    General gene information

    Homology

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    cadmium ion transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    cadmium ion transmembrane transporter activity IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    manganese ion transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    metal ion:proton antiporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    metal ion:proton antiporter activity IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    protein homodimerization activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    transition metal ion transmembrane transporter activity IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    zinc ion transmembrane transporter activity IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    cadmium ion transmembrane transport IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    cellular cadmium ion homeostasis IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    divalent metal ion export ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    iron ion homeostasis IEA
    Inferred from Electronic Annotation
    more info
     
    zinc ion transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
     
    zinc ion transport IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    Component Evidence Code Pubs
    integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    nuclear envelope IDA
    Inferred from Direct Assay
    more info
    PubMed 
    plasma membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    plasma membrane IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 

    General protein information

    Preferred Names
    natural resistance-associated macrophage protein 1
    Names
    NRAMP 1
    natural resistant-associated macrophage protein 1
    solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
    solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_204964.1NP_990295.1  natural resistance-associated macrophage protein 1

      See identical proteins and their annotated locations for NP_990295.1

      Status: PROVISIONAL

      Source sequence(s)
      U40598
      UniProtKB/Swiss-Prot
      P51027
      Related
      ENSGALP00000018625.4, ENSGALT00000018648.4
      Conserved Domains (2) summary
      TIGR01197
      Location:61461
      nramp; NRAMP (natural resistance-associated macrophage protein) metal ion transporters
      pfam01566
      Location:83468
      Nramp; Natural resistance-associated macrophage protein

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 104 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCg6a Primary Assembly

    Genomic

    1. NC_006094.5 Reference GRCg6a Primary Assembly

      Range
      22547347..22552954 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015289783.2XP_015145269.2  natural resistance-associated macrophage protein 1 isoform X2

      Conserved Domains (1) summary
      TIGR01197
      Location:61453
      nramp; NRAMP (natural resistance-associated macrophage protein) metal ion transporters
    2. XM_015289782.2XP_015145268.2  natural resistance-associated macrophage protein 1 isoform X1

      Conserved Domains (1) summary
      TIGR01197
      Location:61461
      nramp; NRAMP (natural resistance-associated macrophage protein) metal ion transporters
    3. XM_015289784.2XP_015145270.2  natural resistance-associated macrophage protein 1 isoform X3

      Conserved Domains (1) summary
      TIGR01197
      Location:61461
      nramp; NRAMP (natural resistance-associated macrophage protein) metal ion transporters
    4. XM_015289785.2XP_015145271.2  natural resistance-associated macrophage protein 1 isoform X4

      Conserved Domains (1) summary
      TIGR01197
      Location:61461
      nramp; NRAMP (natural resistance-associated macrophage protein) metal ion transporters
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