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    Aldh Aldehyde dehydrogenase [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 34256, updated on 8-Oct-2018

    Summary

    Official Symbol
    Aldhprovided by FlyBase
    Official Full Name
    Aldehyde dehydrogenaseprovided by FlyBase
    Primary source
    FLYBASE:FBgn0012036
    Locus tag
    Dmel_CG3752
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster (old-lineage: Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    146084_at; ACDH; ALDH; ALDHA1; CG 3752; CG3752; DmALDH; Dmel\CG3752

    Genomic context

    See Aldh in Genome Data Viewer
    Location:
    30B1-30B1; 2-35 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.13 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (9387389..9391567)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (9387389..9391567)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Shaw-like Neighboring gene ncRNA Neighboring gene uncharacterized protein Neighboring gene Multicopper oxidase-1

    Genomic regions, transcripts, and products

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    aldehyde dehydrogenase (NAD) activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    aldehyde dehydrogenase (NAD) activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    aldehyde dehydrogenase (NAD) activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Process Evidence Code Pubs
    negative regulation of neuron death IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    oxidation-reduction process IEA
    Inferred from Electronic Annotation
    more info
     
    pyruvate metabolic process ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    response to ethanol IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    mitochondrial matrix ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    mitochondrion HDA PubMed 
    mitochondrion IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    aldehyde dehydrogenase
    Names
    Aldh-PA
    Aldh-PB
    CG3752-PA
    CG3752-PB
    acetaldehyde dehydrogenase
    NP_001260290.1
    NP_609285.1

    NCBI Reference Sequences (RefSeq)

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      9387389..9391567
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_135441.2NP_609285.1  aldehyde dehydrogenase, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_609285.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VLC5
      Related
      FBpp0079406, FBtr0079806
      Conserved Domains (2) summary
      cd07141
      Location:34514
      ALDH_F1AB_F2_RALDH1; NAD+-dependent retinal dehydrogenase 1, ALDH families 1A, 1B, and 2-like
      PLN02466
      Location:9512
      PLN02466; aldehyde dehydrogenase family 2 member
    2. NM_001273361.1NP_001260290.1  aldehyde dehydrogenase, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001260290.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VLC5
      Related
      FBpp0304847, FBtr0332597
      Conserved Domains (2) summary
      cd07141
      Location:34514
      ALDH_F1AB_F2_RALDH1; NAD+-dependent retinal dehydrogenase 1, ALDH families 1A, 1B, and 2-like
      PLN02466
      Location:9512
      PLN02466; aldehyde dehydrogenase family 2 member
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