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    vap vacuolar peduncle [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 32569, updated on 19-Aug-2018

    Summary

    Official Symbol
    vapprovided by FlyBase
    Official Full Name
    vacuolar peduncleprovided by FlyBase
    Primary source
    FLYBASE:FBgn0003969
    Locus tag
    Dmel_CG9209
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster (old-lineage: Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG9209; D-RasGAP; Dmel\CG9209; FBpp0073946; p120RasGAP; RAS-GAP; rasGap; RasGap; RasGAP; RasGAP/Vap

    Genomic context

    See vap in Genome Data Viewer
    Location:
    14A5-14A6; 1-52 cM
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    Release 6.13 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (15999951..16005812, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (15893984..15899845, complement)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene extradenticle Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Mucin 14A

    Genomic regions, transcripts, and products

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    GTPase activator activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Process Evidence Code Pubs
    behavioral response to ethanol IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    mushroom body development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of GTPase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    regulation of endocytosis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of growth IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    vacuolar peduncle
    Names
    CG9209-PA
    CG9209-PB
    CG9209-PC
    CG9209-PD
    CG9209-PE
    CG9209-PF
    Ras GTPase-activating protein
    vacuolar peduncule
    vacuolar pedunculi
    vap-PA
    vap-PB
    vap-PC
    vap-PD
    vap-PE
    vap-PF

    NCBI Reference Sequences (RefSeq)

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      15999951..16005812 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001298385.1NP_001285314.1  vacuolar peduncle, isoform E [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001285314.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8IR23
      Related
      FBpp0309361.1, FBtr0340415
      Conserved Domains (8) summary
      cd08400
      Location:499622
      C2_Ras_p21A1; C2 domain present in RAS p21 protein activator 1 (RasA1)
      cd10353
      Location:64166
      SH2_Nterm_RasGAP; N-terminal Src homology 2 (SH2) domain found in Ras GTPase-activating protein 1 (GAP)
      cd10354
      Location:252326
      SH2_Cterm_RasGAP; C-terminal Src homology 2 (SH2) domain found in Ras GTPase-activating protein 1 (GAP)
      cd11788
      Location:183241
      SH3_RasGAP; Src Homology 3 domain of Ras GTPase-Activating Protein 1
      smart00323
      Location:605953
      RasGAP; GTPase-activator protein for Ras-like GTPases
      cd13260
      Location:379484
      PH_RASA1; RAS p21 protein activator (GTPase activating protein) 1 Pleckstrin homology (PH) domain
      pfam00169
      Location:381484
      PH; PH domain
      cl02569
      Location:620954
      RasGAP; Ras GTPase Activating Domain
    2. NM_078637.3NP_523361.1  vacuolar peduncle, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_523361.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8IR23
      Related
      FBpp0073945.1, FBtr0074140
      Conserved Domains (8) summary
      cd08400
      Location:499622
      C2_Ras_p21A1; C2 domain present in RAS p21 protein activator 1 (RasA1)
      cd10353
      Location:64166
      SH2_Nterm_RasGAP; N-terminal Src homology 2 (SH2) domain found in Ras GTPase-activating protein 1 (GAP)
      cd10354
      Location:252326
      SH2_Cterm_RasGAP; C-terminal Src homology 2 (SH2) domain found in Ras GTPase-activating protein 1 (GAP)
      cd11788
      Location:183241
      SH3_RasGAP; Src Homology 3 domain of Ras GTPase-Activating Protein 1
      smart00323
      Location:605953
      RasGAP; GTPase-activator protein for Ras-like GTPases
      cd13260
      Location:379484
      PH_RASA1; RAS p21 protein activator (GTPase activating protein) 1 Pleckstrin homology (PH) domain
      pfam00169
      Location:381484
      PH; PH domain
      cl02569
      Location:620954
      RasGAP; Ras GTPase Activating Domain
    3. NM_167480.2NP_727925.1  vacuolar peduncle, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_727925.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8IR23
      Related
      FBpp0073946.1, FBtr0074141
      Conserved Domains (8) summary
      cd08400
      Location:499622
      C2_Ras_p21A1; C2 domain present in RAS p21 protein activator 1 (RasA1)
      cd10353
      Location:64166
      SH2_Nterm_RasGAP; N-terminal Src homology 2 (SH2) domain found in Ras GTPase-activating protein 1 (GAP)
      cd10354
      Location:252326
      SH2_Cterm_RasGAP; C-terminal Src homology 2 (SH2) domain found in Ras GTPase-activating protein 1 (GAP)
      cd11788
      Location:183241
      SH3_RasGAP; Src Homology 3 domain of Ras GTPase-Activating Protein 1
      smart00323
      Location:605953
      RasGAP; GTPase-activator protein for Ras-like GTPases
      cd13260
      Location:379484
      PH_RASA1; RAS p21 protein activator (GTPase activating protein) 1 Pleckstrin homology (PH) domain
      pfam00169
      Location:381484
      PH; PH domain
      cl02569
      Location:620954
      RasGAP; Ras GTPase Activating Domain
    4. NM_206759.2NP_996482.1  vacuolar peduncle, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_996482.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8IR23
      Related
      FBpp0089148.1, FBtr0074143
      Conserved Domains (8) summary
      cd08400
      Location:499622
      C2_Ras_p21A1; C2 domain present in RAS p21 protein activator 1 (RasA1)
      cd10353
      Location:64166
      SH2_Nterm_RasGAP; N-terminal Src homology 2 (SH2) domain found in Ras GTPase-activating protein 1 (GAP)
      cd10354
      Location:252326
      SH2_Cterm_RasGAP; C-terminal Src homology 2 (SH2) domain found in Ras GTPase-activating protein 1 (GAP)
      cd11788
      Location:183241
      SH3_RasGAP; Src Homology 3 domain of Ras GTPase-Activating Protein 1
      smart00323
      Location:605953
      RasGAP; GTPase-activator protein for Ras-like GTPases
      cd13260
      Location:379484
      PH_RASA1; RAS p21 protein activator (GTPase activating protein) 1 Pleckstrin homology (PH) domain
      pfam00169
      Location:381484
      PH; PH domain
      cl02569
      Location:620954
      RasGAP; Ras GTPase Activating Domain
    5. NM_167481.3NP_727926.2  vacuolar peduncle, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_727926.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8IR23
      Related
      FBpp0089147.1, FBtr0074142
      Conserved Domains (8) summary
      cd08400
      Location:499622
      C2_Ras_p21A1; C2 domain present in RAS p21 protein activator 1 (RasA1)
      cd10353
      Location:64166
      SH2_Nterm_RasGAP; N-terminal Src homology 2 (SH2) domain found in Ras GTPase-activating protein 1 (GAP)
      cd10354
      Location:252326
      SH2_Cterm_RasGAP; C-terminal Src homology 2 (SH2) domain found in Ras GTPase-activating protein 1 (GAP)
      cd11788
      Location:183241
      SH3_RasGAP; Src Homology 3 domain of Ras GTPase-Activating Protein 1
      smart00323
      Location:605953
      RasGAP; GTPase-activator protein for Ras-like GTPases
      cd13260
      Location:379484
      PH_RASA1; RAS p21 protein activator (GTPase activating protein) 1 Pleckstrin homology (PH) domain
      pfam00169
      Location:381484
      PH; PH domain
      cl02569
      Location:620954
      RasGAP; Ras GTPase Activating Domain
    6. NM_001298386.1NP_001285315.1  vacuolar peduncle, isoform F [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001285315.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8IR23
      Related
      FBpp0309362.1, FBtr0340416
      Conserved Domains (8) summary
      cd08400
      Location:499622
      C2_Ras_p21A1; C2 domain present in RAS p21 protein activator 1 (RasA1)
      cd10353
      Location:64166
      SH2_Nterm_RasGAP; N-terminal Src homology 2 (SH2) domain found in Ras GTPase-activating protein 1 (GAP)
      cd10354
      Location:252326
      SH2_Cterm_RasGAP; C-terminal Src homology 2 (SH2) domain found in Ras GTPase-activating protein 1 (GAP)
      cd11788
      Location:183241
      SH3_RasGAP; Src Homology 3 domain of Ras GTPase-Activating Protein 1
      smart00323
      Location:605953
      RasGAP; GTPase-activator protein for Ras-like GTPases
      cd13260
      Location:379484
      PH_RASA1; RAS p21 protein activator (GTPase activating protein) 1 Pleckstrin homology (PH) domain
      pfam00169
      Location:381484
      PH; PH domain
      cl02569
      Location:620954
      RasGAP; Ras GTPase Activating Domain
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