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    Tmcc2 transmembrane and coiled-coil domain family 2 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 305095, updated on 13-Aug-2019

    Summary

    Official Symbol
    Tmcc2provided by RGD
    Official Full Name
    transmembrane and coiled-coil domain family 2provided by RGD
    Primary source
    RGD:1311960
    See related
    Ensembl:ENSRNOG00000000033
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1311960
    Expression
    Biased expression in Spleen (RPKM 290.1), Lung (RPKM 149.8) and 3 other tissues See more
    Orthologs

    Genomic context

    See Tmcc2 in Genome Data Viewer
    Location:
    13q13
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    106 current Rnor_6.0 (GCF_000001895.5) 13 NC_005112.4 (49132685..49169771, complement)
    106 current Rn_Celera (GCF_000002265.2) 13 AC_000081.1 (44128734..44166110, complement)
    104 previous assembly Rnor_5.0 (GCF_000001895.4) 13 NC_005112.3 (54201418..54238775, complement)

    Chromosome 13 - NC_005112.4Genomic Context describing neighboring genes Neighboring gene kelch domain containing 8A Neighboring gene NUAK family kinase 2 Neighboring gene dual serine/threonine and tyrosine protein kinase Neighboring gene RB binding protein 5, histone lysine methyltransferase complex subunit

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    amyloid precursor protein metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    amyloid precursor protein metabolic process ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    Component Evidence Code Pubs
    endoplasmic reticulum IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    endoplasmic reticulum ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    transmembrane and coiled-coil domains protein 2
    Names
    transmembrane and coiled-coil domains 2

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001305128.1NP_001292057.1  transmembrane and coiled-coil domains protein 2

      See identical proteins and their annotated locations for NP_001292057.1

      Status: VALIDATED

      Source sequence(s)
      AABR07020967, AABR07020968
      UniProtKB/TrEMBL
      D3ZE26
      Related
      ENSRNOP00000000036.3, ENSRNOT00000000036.5
      Conserved Domains (1) summary
      pfam10267
      Location:286692
      Tmemb_cc2; Predicted transmembrane and coiled-coil 2 protein

    RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Rnor_6.0 Primary Assembly

    Genomic

    1. NC_005112.4 Reference Rnor_6.0 Primary Assembly

      Range
      49132685..49169771 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_003751237.4XP_003751285.1  transmembrane and coiled-coil domains protein 2 isoform X1

      See identical proteins and their annotated locations for XP_003751285.1

      Conserved Domains (1) summary
      pfam10267
      Location:208614
      Tmemb_cc2; Predicted transmembrane and coiled-coil 2 protein
    2. XM_006249803.3XP_006249865.1  transmembrane and coiled-coil domains protein 2 isoform X4

      See identical proteins and their annotated locations for XP_006249865.1

      Conserved Domains (1) summary
      pfam10267
      Location:50456
      Tmemb_cc2; Predicted transmembrane and coiled-coil 2 protein
    3. XM_008769513.2XP_008767735.1  transmembrane and coiled-coil domains protein 2 isoform X3

      See identical proteins and their annotated locations for XP_008767735.1

      Conserved Domains (1) summary
      pfam10267
      Location:96502
      Tmemb_cc2; Predicted transmembrane and coiled-coil 2 protein
    4. XM_006249802.3XP_006249864.1  transmembrane and coiled-coil domains protein 2 isoform X2

      See identical proteins and their annotated locations for XP_006249864.1

      Conserved Domains (1) summary
      pfam10267
      Location:100506
      Tmemb_cc2; Predicted transmembrane and coiled-coil 2 protein

    Alternate Rn_Celera

    Genomic

    1. AC_000081.1 Alternate Rn_Celera

      Range
      44128734..44166110 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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