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    Dhx40 DEAH-box helicase 40 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 287595, updated on 12-Aug-2018

    Summary

    Official Symbol
    Dhx40provided by RGD
    Official Full Name
    DEAH-box helicase 40provided by RGD
    Primary source
    RGD:1359618
    See related
    Ensembl:ENSRNOG00000004549
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Expression
    Biased expression in Kidney (RPKM 218.7), Testes (RPKM 177.6) and 9 other tissues See more
    Orthologs

    Genomic context

    See Dhx40 in Genome Data Viewer
    Location:
    10q26
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    106 current Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (74081442..74119032, complement)
    104 previous assembly Rnor_5.0 (GCF_000001895.4) 10 NC_005109.3 (75981100..76019044)

    Chromosome 10 - NC_005109.4Genomic Context describing neighboring genes Neighboring gene peptidyl-tRNA hydrolase 2 Neighboring gene clathrin heavy chain Neighboring gene uncharacterized LOC103693408 Neighboring gene yippee-like 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Homology

    Clone Names

    • MGC94894

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    ATP-dependent 3'-5' RNA helicase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Process Evidence Code Pubs
    mRNA splicing, via spliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    probable ATP-dependent RNA helicase DHX40
    Names
    DEAH (Asp-Glu-Ala-His) box polypeptide 40
    DEAH box protein 40
    NP_001005873.1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001005873.1NP_001005873.1  probable ATP-dependent RNA helicase DHX40

      See identical proteins and their annotated locations for NP_001005873.1

      Status: PROVISIONAL

      Source sequence(s)
      BC083821
      UniProtKB/Swiss-Prot
      Q5XI69
      Related
      ENSRNOP00000006926.3, ENSRNOT00000006926.4
      Conserved Domains (5) summary
      smart00490
      Location:312399
      HELICc; helicase superfamily c-terminal domain
      smart00487
      Location:48236
      DEXDc; DEAD-like helicases superfamily
      smart00847
      Location:469557
      HA2; Helicase associated domain (HA2) Add an annotation
      cd00046
      Location:78213
      DEXDc; DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
      pfam07717
      Location:591699
      OB_NTP_bind; Oligonucleotide/oligosaccharide-binding (OB)-fold

    RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Rnor_6.0 Primary Assembly

    Genomic

    1. NC_005109.4 Reference Rnor_6.0 Primary Assembly

      Range
      74081442..74119032 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate Rn_Celera

    Genomic

    1. AC_000078.1 Alternate Rn_Celera

      Range
      70504530..70541105 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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