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    Slc15a3 solute carrier family 15 member 3 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 246239, updated on 13-Aug-2019

    Summary

    Official Symbol
    Slc15a3provided by RGD
    Official Full Name
    solute carrier family 15 member 3provided by RGD
    Primary source
    RGD:628663
    See related
    Ensembl:ENSRNOG00000021644
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Pht2
    Summary
    may play a role in protein catabolism in the lymphatic system [RGD, Feb 2006]
    Expression
    Biased expression in Spleen (RPKM 117.6), Thymus (RPKM 74.8) and 9 other tissues See more
    Orthologs

    Genomic context

    See Slc15a3 in Genome Data Viewer
    Location:
    1q43
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    106 current Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (226896387..226912644)
    106 current Rn_Celera (GCF_000002265.2) 1 AC_000069.1 (204984950..204999742)
    104 previous assembly Rnor_5.0 (GCF_000001895.4) 1 NC_005100.3 (233963402..233978193)

    Chromosome 1 - NC_005100.4Genomic Context describing neighboring genes Neighboring gene VPS37C subunit of ESCRT-I Neighboring gene Cd5 molecule Neighboring gene Cd6 molecule Neighboring gene transmembrane protein 132A Neighboring gene transmembrane protein 109 Neighboring gene pre-mRNA processing factor 19

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    oligopeptide transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    peptide transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    peptide:proton symporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    proton-dependent oligopeptide secondary active transmembrane transporter activity TAS
    Traceable Author Statement
    more info
    PubMed 
    Process Evidence Code Pubs
    oligopeptide transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
     
    protein catabolic process NAS
    Non-traceable Author Statement
    more info
    PubMed 
    protein transport IEA
    Inferred from Electronic Annotation
    more info
     
    proton transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    integral component of membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    intracellular membrane-bounded organelle ISO
    Inferred from Sequence Orthology
    more info
     
    lysosomal membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    lysosomal membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    solute carrier family 15 member 3
    Names
    peptide transporter 3
    peptide/histidine transporter 2
    peptide/histidine transporter PHT2
    solute carrier family 15 (oligopeptide transporter), member 3

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_139341.1NP_647557.1  solute carrier family 15 member 3

      See identical proteins and their annotated locations for NP_647557.1

      Status: PROVISIONAL

      Source sequence(s)
      AB026665
      UniProtKB/Swiss-Prot
      Q924V4
      Related
      ENSRNOP00000034275.2, ENSRNOT00000029443.3
      Conserved Domains (2) summary
      COG3104
      Location:41572
      PTR2; Dipeptide/tripeptide permease [Amino acid transport and metabolism]
      cl21472
      Location:177521
      MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...

    RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Rnor_6.0 Primary Assembly

    Genomic

    1. NC_005100.4 Reference Rnor_6.0 Primary Assembly

      Range
      226896387..226912644
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017588784.1XP_017444273.1  solute carrier family 15 member 3 isoform X1

      UniProtKB/Swiss-Prot
      Q924V4

    Alternate Rn_Celera

    Genomic

    1. AC_000069.1 Alternate Rn_Celera

      Range
      204984950..204999742
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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