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    gbh-2 Gamma Butyrobetaine Hydroxylase [ Caenorhabditis elegans ]

    Gene ID: 174358, updated on 5-Aug-2018

    Summary

    Gene symbol
    gbh-2
    Gene description
    Gamma Butyrobetaine Hydroxylase
    Primary source
    WormBase:WBGene00001523
    Locus tag
    CELE_M05D6.7
    Gene type
    protein coding
    RNA name
    Gamma Butyrobetaine Hydroxylase
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis

    Genomic context

    See gbh-2 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    6
    Sequence:
    Chromosome: II; NC_003280.10 (8485938..8487509)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene hypothetical protein Neighboring gene hypothetical protein Neighboring gene Tyrosine-protein phosphatase Neighboring gene ncRNA Neighboring gene hypothetical protein

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    iron ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
     
    oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    trimethyllysine dioxygenase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    carnitine biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    carnitine biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
     
    oxidation-reduction process IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    Gamma Butyrobetaine Hydroxylase
    NP_495793.2
    • Product from WormBase gene class gbh;
      Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      8485938..8487509
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_063392.2NP_495793.2  Gamma Butyrobetaine Hydroxylase [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_495793.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q21526
      Conserved Domains (3) summary
      cd00250
      Location:129391
      CAS_like; Clavaminic acid synthetase (CAS) -like; CAS is a trifunctional Fe(II)/ 2-oxoglutarate (2OG) oxygenase carrying out three reactions in the biosynthesis of clavulanic acid, an inhibitor of class A serine beta-lactamases. In general, Fe(II)-2OG oxygenases ...
      TIGR02410
      Location:43402
      carnitine_TMLD; trimethyllysine dioxygenase
      cl01414
      Location:22104
      DUF971; Protein of unknown function (DUF971)
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