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    Tas1r1 taste receptor, type 1, member 1 [ Mus musculus (house mouse) ]

    Gene ID: 110326, updated on 18-Sep-2018

    Summary

    Official Symbol
    Tas1r1provided by MGI
    Official Full Name
    taste receptor, type 1, member 1provided by MGI
    Primary source
    MGI:MGI:1927505
    See related
    Ensembl:ENSMUSG00000028950 Vega:OTTMUSG00000010375
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    TR1; T1r1; Gpr70
    Expression
    Biased expression in testis adult (RPKM 16.2), genital fat pad adult (RPKM 1.6) and 2 other tissues See more
    Orthologs

    Genomic context

    See Tas1r1 in Genome Data Viewer
    Location:
    4 E2; 4 82.83 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 4 NC_000070.6 (152027914..152038490, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 4 NC_000070.5 (151402023..151412599, complement)

    Chromosome 4 - NC_000070.6Genomic Context describing neighboring genes Neighboring gene kelch-like 21 Neighboring gene zinc finger and BTB domain containing 48 Neighboring gene nucleolar protein 9 Neighboring gene pleckstrin homology domain containing, family G (with RhoGef domain) member 5

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from BioSystems

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    G protein-coupled receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    taste receptor activity ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    G protein-coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
     
    response to stimulus IEA
    Inferred from Electronic Annotation
    more info
     
    sensory perception of taste IEA
    Inferred from Electronic Annotation
    more info
     
    sensory perception of umami taste IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    sensory perception of umami taste ISO
    Inferred from Sequence Orthology
    more info
     
    signal transduction IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    integral component of plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    membrane IEA
    Inferred from Electronic Annotation
    more info
     
    plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    taste receptor type 1 member 1
    Names
    G-protein coupled receptor 70
    candidate taste receptor T1R1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_031867.2NP_114073.1  taste receptor type 1 member 1 precursor

      See identical proteins and their annotated locations for NP_114073.1

      Status: VALIDATED

      Source sequence(s)
      AF337040
      Consensus CDS
      CCDS18985.1
      UniProtKB/Swiss-Prot
      Q99PG6
      UniProtKB/TrEMBL
      Q3U5H1
      Related
      ENSMUSP00000030792.1, OTTMUSP00000011121, ENSMUST00000030792.1, OTTMUST00000024187
      Conserved Domains (4) summary
      cd06363
      Location:33487
      PBP1_Taste_receptor; Ligand-binding domain of the T1R taste receptor
      pfam00003
      Location:589815
      7tm_3; 7 transmembrane sweet-taste receptor of 3 GCPR
      pfam01094
      Location:75458
      ANF_receptor; Receptor family ligand binding region
      pfam07562
      Location:495545
      NCD3G; Nine Cysteines Domain of family 3 GPCR

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000070.6 Reference GRCm38.p4 C57BL/6J

      Range
      152027914..152038490 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006538474.3XP_006538537.1  taste receptor type 1 member 1 isoform X1

      Conserved Domains (4) summary
      pfam00003
      Location:462688
      7tm_3; 7 transmembrane sweet-taste receptor of 3 GCPR
      pfam01094
      Location:40331
      ANF_receptor; Receptor family ligand binding region
      pfam07562
      Location:368418
      NCD3G; Nine Cysteines Domain of family 3 GPCR
      cl10011
      Location:33360
      Periplasmic_Binding_Protein_Type_1; Type 1 periplasmic binding fold superfamily
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