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    TAAR2 trace amine associated receptor 2 [ Homo sapiens (human) ]

    Gene ID: 9287, updated on 11-Jun-2021

    Summary

    Official Symbol
    TAAR2provided by HGNC
    Official Full Name
    trace amine associated receptor 2provided by HGNC
    Primary source
    HGNC:HGNC:4514
    See related
    Ensembl:ENSG00000146378 MIM:604849
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    GPR58; taR-2
    Expression
    Low expression observed in reference dataset See more
    Orthologs
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    Genomic context

    See TAAR2 in Genome Data Viewer
    Location:
    6q23.2
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    109.20210514 current GRCh38.p13 (GCF_000001405.39) 6 NC_000006.12 (132617150..132624275, complement)
    105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 6 NC_000006.11 (132938289..132945414, complement)

    Chromosome 6 - NC_000006.12Genomic Context describing neighboring genes Neighboring gene trace amine associated receptor 5 Neighboring gene trace amine associated receptor 4, pseudogene Neighboring gene trace amine associated receptor 3, pseudogene Neighboring gene trace amine associated receptor 1 Neighboring gene HLF pseudogene 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Homology

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables G protein-coupled receptor activity TAS
    Traceable Author Statement
    more info
    PubMed 
    enables trace-amine receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in G protein-coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    trace amine-associated receptor 2
    Names
    G protein-coupled receptor 58

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001033080.1NP_001028252.1  trace amine-associated receptor 2 isoform 1

      See identical proteins and their annotated locations for NP_001028252.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
      Source sequence(s)
      AY703480
      Consensus CDS
      CCDS34541.1
      UniProtKB/Swiss-Prot
      Q9P1P5
      Related
      ENSP00000356908.1, ENST00000367931.1
      Conserved Domains (2) summary
      pfam00001
      Location:60315
      7tm_1; 7 transmembrane receptor (rhodopsin family)
      cl21561
      Location:53180
      7tm_4; Olfactory receptor
    2. NM_014626.3NP_055441.2  trace amine-associated receptor 2 isoform 2

      See identical proteins and their annotated locations for NP_055441.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks part of the 5' coding region, compared to variant 1. The encoded isoform (2) is shorter, compared to isoform 1.
      Source sequence(s)
      AY702304, DN693314
      Consensus CDS
      CCDS5157.1
      UniProtKB/Swiss-Prot
      Q9P1P5
      Related
      ENSP00000275191.2, ENST00000275191.2
      Conserved Domains (2) summary
      pfam00001
      Location:15270
      7tm_1; 7 transmembrane receptor (rhodopsin family)
      cl21561
      Location:8135
      7tm_4; Olfactory receptor

    RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p13 Primary Assembly

    Genomic

    1. NC_000006.12 Reference GRCh38.p13 Primary Assembly

      Range
      132617150..132624275 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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