Format

Send to:

Choose Destination
    • Showing Current items.

    MET1 methyltransferase 1 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 834975, updated on 10-Oct-2019

    Summary

    Gene symbol
    MET1
    Gene description
    methyltransferase 1
    Primary source
    Araport:AT5G49160
    Locus tag
    AT5G49160
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliophyta; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    DDM2; DECREASED DNA METHYLATION 2; DMT01; DMT1; DNA METHYLTRANSFERASE; DNA METHYLTRANSFERASE 01; DNA METHYLTRANSFERASE 1; MET2; methyltransferase 1; METHYLTRANSFERASE 2; METHYLTRANSFERASE I; METI
    Summary
    Encodes a cytosine methyltransferase MET1. Required for silencing of FWA paternal allele in endosperm. Two lines with RNAi constructs directed against DMT1 have reduced agrobacterium-mediated tumor formation.

    Genomic context

    See MET1 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    12
    Sequence:
    Chromosome: 5; NC_003076.8 (19932114..19938470)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene Disease resistance protein (TIR-NBS-LRR class) family Neighboring gene ncRNA Neighboring gene gamete expressed 2 Neighboring gene hypothetical protein Neighboring gene Plant invertase/pectin methylesterase inhibitor superfamily

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Homology

    NM_001344823.1
    NM_124293.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    DNA (cytosine-5-)-methyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    chromatin binding IEA
    Inferred from Electronic Annotation
    more info
     
    methyltransferase activity TAS
    Traceable Author Statement
    more info
    PubMed 
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    C-5 methylation of cytosine IEA
    Inferred from Electronic Annotation
    more info
     
    DNA mediated transformation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    DNA methylation on cytosine within a CG sequence IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    DNA methylation on cytosine within a CG sequence IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    chromatin organization IEA
    Inferred from Electronic Annotation
    more info
     
    maintenance of DNA methylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    maintenance of DNA methylation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    negative regulation of flower development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of gene expression by genetic imprinting IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    zygote asymmetric cytokinesis in embryo sac IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    nucleus ISM
    Inferred from Sequence Model
    more info
     

    General protein information

    Preferred Names
    methyltransferase 1
    NP_199727.1
    • methyltransferase 1 (MET1); FUNCTIONS IN: methyltransferase activity; INVOLVED IN: in 6 processes; LOCATED IN: nucleus; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: DNA (cytosine-5)-methyltransferase 1 (InterPro:IPR017198), DNA methylase, C-5 cytosine-specific (InterPro:IPR001525), Bromo adjacent homology (BAH) domain (InterPro:IPR001025), DNA methylase, C-5 cytosine-specific, active site (InterPro:IPR018117); BEST Arabidopsis thaliana protein match is: DNA (cytosine-5-)-methyltransferase family protein (TAIR:AT4G08990.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      19932114..19938470
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_124293.4NP_199727.1  methyltransferase 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_199727.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P34881
      UniProtKB/TrEMBL
      A0A178UE49
      Conserved Domains (4) summary
      COG0270
      Location:10951525
      Dcm; Site-specific DNA-cytosine methylase [Replication, recombination and repair]
      cd04708
      Location:9041105
      BAH_plantDCM_II; BAH, or Bromo Adjacent Homology domain, second copy present in DNA (Cytosine-5)-methyltransferases (DCM) from plants. DNA methylation, or the covalent addition of a methyl group to cytosine within the context of the CpG dinucleotide, has profound effects ...
      cd04712
      Location:732869
      BAH_DCM_I; BAH, or Bromo Adjacent Homology domain, as present in DNA (Cytosine-5)-methyltransferases (DCM) 1. DNA methylation, or the covalent addition of a methyl group to cytosine within the context of the CpG dinucleotide, has profound effects on the genome. ...
      pfam12047
      Location:79214
      DNMT1-RFD; Cytosine specific DNA methyltransferase replication foci domain
    2. NM_001344823.1NP_001331134.1  methyltransferase 1 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8BCY7
    Support Center