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    POLH DNA polymerase eta [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 700772, updated on 29-Apr-2017
    Gene symbol
    POLH
    Gene description
    DNA polymerase eta
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    Location:
    chromosome: 4
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    102 current Mmul_8.0.1 (GCF_000772875.2) 4 NC_027896.1 (44643444..44681342)
    Build 1.2 previous assembly Mmul_051212 (GCF_000002255.3) 4 NC_007861.1 (43477684..43514460)

    Chromosome 4 - NC_027896.1Genomic Context describing neighboring genes Neighboring gene RNA polymerase I and III subunit C Neighboring gene exportin 5 Neighboring gene GTP binding protein 2 Neighboring gene MAD2L1 binding protein

    • Fanconi anemia pathway, organism-specific biosystem (from KEGG)
      Fanconi anemia pathway, organism-specific biosystemThe Fanconi anemia pathway is required for the efficient repair of damaged DNA, especially interstrand cross-links (ICLs). DNA ICL is directly recognized by FANCM and associated proteins, that recrui...
    • Fanconi anemia pathway, conserved biosystem (from KEGG)
      Fanconi anemia pathway, conserved biosystemThe Fanconi anemia pathway is required for the efficient repair of damaged DNA, especially interstrand cross-links (ICLs). DNA ICL is directly recognized by FANCM and associated proteins, that recrui...
    • Platinum drug resistance, organism-specific biosystem (from KEGG)
      Platinum drug resistance, organism-specific biosystemPlatinum-based drugs cisplatin, carboplatin and oxaliplatin are widely used in the therapy of solid malignancies, including testicular, ovarian, head and neck, colorectal, bladder and lung cancers. T...
    • Platinum drug resistance, conserved biosystem (from KEGG)
      Platinum drug resistance, conserved biosystemPlatinum-based drugs cisplatin, carboplatin and oxaliplatin are widely used in the therapy of solid malignancies, including testicular, ovarian, head and neck, colorectal, bladder and lung cancers. T...

    Markers

    Homology

    Preferred Names
    DNA polymerase eta
    Names
    polymerase (DNA directed), eta
    XP_014991918.1
    XP_014991919.1

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 102 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_8.0.1 Primary Assembly

    Genomic

    1. NC_027896.1 Reference Mmul_8.0.1 Primary Assembly

      Range
      44643444..44681342
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015136432.1XP_014991918.1  DNA polymerase eta isoform X1

      Conserved Domains (2) summary
      cd01702
      Location:10428
      PolY_Pol_eta; DNA Polymerase eta
      COG0389
      Location:7354
      DinP; Nucleotidyltransferase/DNA polymerase involved in DNA repair [Replication, recombination and repair]
    2. XM_015136433.1XP_014991919.1  DNA polymerase eta isoform X2

      Conserved Domains (1) summary
      cl12025
      Location:66304
      PolY; Y-family of DNA polymerases
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