as3mt arsenite methyltransferase [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: as3mtprovided by ZNC
Official Full Name: arsenite methyltransferaseprovided by ZNC
Primary source: ZFIN:ZDB-GENE-060312-15
See related: Ensembl:ENSDARG00000027572 AllianceGenome:ZFIN:ZDB-GENE-060312-15
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:136933
Summary: Predicted to enable arsenite methyltransferase activity. Predicted to be involved in arsonoacetate metabolic process and toxin metabolic process. Predicted to act upstream of or within methylation. Predicted to be active in cytosol. Is expressed in liver. Orthologous to human AS3MT (arsenite methyltransferase). [provided by Alliance of Genome Resources, Apr 2025]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 1

Exon count:: 11

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	1	NC_007112.7 (31706677..31722868)
105	previous assembly	GRCz10 (GCF_000002035.5)	1	NC_007112.6 (30974109..30990300)

Chromosome 1 - NC_007112.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables arsenite methyltransferase activity	IBA Inferred from Biological aspect of Ancestor more info
enables arsenite methyltransferase activity	IEA Inferred from Electronic Annotation more info
enables methyltransferase activity	IEA Inferred from Electronic Annotation more info
enables transferase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in arsonoacetate metabolic process	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within methylation	IEA Inferred from Electronic Annotation more info
involved_in toxin metabolic process	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in cytosol	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: arsenite methyltransferase

Names: arsenic (+3 oxidation state) methyltransferase

NP_001034928.1

EC 2.1.1.137

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.