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    AIDA axin interactor, dorsalization associated [ Homo sapiens (human) ]

    Gene ID: 64853, updated on 12-Oct-2019

    Summary

    Official Symbol
    AIDAprovided by HGNC
    Official Full Name
    axin interactor, dorsalization associatedprovided by HGNC
    Primary source
    HGNC:HGNC:25761
    See related
    Ensembl:ENSG00000186063 MIM:612375
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    C1orf80
    Expression
    Ubiquitous expression in fat (RPKM 42.6), testis (RPKM 31.5) and 25 other tissues See more
    Orthologs

    Genomic context

    See AIDA in Genome Data Viewer
    Location:
    1q41
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    109.20190905 current GRCh38.p13 (GCF_000001405.39) 1 NC_000001.11 (222668013..222712895, complement)
    105 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (222841355..222886602, complement)

    Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC107985318 Neighboring gene prefoldin subunit 5 pseudogene Neighboring gene MIA SH3 domain ER export factor 3 Neighboring gene uncharacterized LOC105372984 Neighboring gene BRO1 domain and CAAX motif containing Neighboring gene family with sequence similarity 177 member B Neighboring gene dispatched RND transporter family member 1 Neighboring gene NADH:ubiquinone oxidoreductase subunit B1 pseudogene 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • FLJ12806, FLJ32421

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    phosphatidylinositol binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    protein domain specific binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    determination of ventral identity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    dorsal/ventral pattern formation ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    negative regulation of JNK cascade ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    negative regulation of JUN kinase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    regulation of protein complex assembly IEA
    Inferred from Electronic Annotation
    more info
     
    regulation of protein homodimerization activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    cellular_component ND
    No biological Data available
    more info
     
    cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    axin interactor, dorsalization-associated protein
    Names
    axin interaction partner and dorsalization antagonist

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_022831.4NP_073742.2  axin interactor, dorsalization-associated protein

      See identical proteins and their annotated locations for NP_073742.2

      Status: VALIDATED

      Source sequence(s)
      AL392172, AL592148
      Consensus CDS
      CCDS1533.1
      UniProtKB/Swiss-Prot
      Q96BJ3
      Related
      ENSP00000339161.6, ENST00000340020.11
      Conserved Domains (2) summary
      pfam08910
      Location:9112
      Aida_N; Aida N-terminus
      pfam14186
      Location:162300
      Aida_C2; Cytoskeletal adhesion

    RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109.20190905

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p13 Primary Assembly

    Genomic

    1. NC_000001.11 Reference GRCh38.p13 Primary Assembly

      Range
      222668013..222712895 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    RNA

    1. XR_921909.3 RNA Sequence

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