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    Mybbp1a MYB binding protein 1a [ Rattus norvegicus (Norway rat) ]

    Gene ID: 60571, updated on 12-Aug-2018

    Summary

    Official Symbol
    Mybbp1aprovided by RGD
    Official Full Name
    MYB binding protein 1aprovided by RGD
    Primary source
    RGD:62062
    See related
    Ensembl:ENSRNOG00000015236
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    DBP
    Summary
    transcriptional activator that displays a circadian rhythm of expression in hepatocytes [RGD, Feb 2006]
    Expression
    Biased expression in Muscle (RPKM 218.6), Adrenal (RPKM 217.7) and 9 other tissues See more
    Orthologs

    Genomic context

    See Mybbp1a in Genome Data Viewer
    Location:
    10q24
    Exon count:
    26
    Annotation release Status Assembly Chr Location
    106 current Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (59000400..59010794)
    104 previous assembly Rnor_5.0 (GCF_000001895.4) 10 NC_005109.3 (58739440..58749828)

    Chromosome 10 - NC_005109.4Genomic Context describing neighboring genes Neighboring gene smoothelin-like 2 Neighboring gene gamma-glutamyl transferase 6 Neighboring gene sphingolipid transporter 2 Neighboring gene sphingolipid transporter 3 Neighboring gene ubiquitin-conjugating enzyme E2G 1 Neighboring gene small nuclear ribonucleoprotein G pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Pathways from BioSystems

    General gene information

    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    E-box binding IEA
    Inferred from Electronic Annotation
    more info
     
    E-box binding ISO
    Inferred from Sequence Orthology
    more info
     
    sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    sequence-specific DNA binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    transcription corepressor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    transcription corepressor activity ISO
    Inferred from Sequence Orthology
    more info
     
    transcription corepressor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    transcription factor binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    cellular response to glucose starvation IEA
    Inferred from Electronic Annotation
    more info
     
    cellular response to glucose starvation ISO
    Inferred from Sequence Orthology
    more info
     
    circadian regulation of gene expression ISO
    Inferred from Sequence Orthology
    more info
     
    circadian regulation of gene expression ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    intrinsic apoptotic signaling pathway by p53 class mediator IEA
    Inferred from Electronic Annotation
    more info
     
    intrinsic apoptotic signaling pathway by p53 class mediator ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of transcription, DNA-templated ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of transcription, DNA-templated ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    positive regulation of anoikis IEA
    Inferred from Electronic Annotation
    more info
     
    positive regulation of anoikis ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of cell cycle arrest IEA
    Inferred from Electronic Annotation
    more info
     
    positive regulation of cell cycle arrest ISO
    Inferred from Sequence Orthology
    more info
     
    respiratory electron transport chain IEA
    Inferred from Electronic Annotation
    more info
     
    respiratory electron transport chain ISO
    Inferred from Sequence Orthology
    more info
     
    transcription, DNA-templated IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    NLS-dependent protein nuclear import complex ISO
    Inferred from Sequence Orthology
    more info
     
    NLS-dependent protein nuclear import complex ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    cytoplasm ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    intracellular membrane-bounded organelle ISO
    Inferred from Sequence Orthology
    more info
     
    nucleolus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    nucleolus ISO
    Inferred from Sequence Orthology
    more info
     
    nucleolus ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    General protein information

    Preferred Names
    myb-binding protein 1A
    Names
    MYB binding protein (P160) 1a
    PAR-interacting protein
    PIP

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_031668.1NP_113856.1  myb-binding protein 1A

      See identical proteins and their annotated locations for NP_113856.1

      Status: PROVISIONAL

      Source sequence(s)
      U83590
      UniProtKB/Swiss-Prot
      O35821
      Conserved Domains (3) summary
      pfam04931
      Location:3766
      DNA_pol_phi; DNA polymerase phi
      pfam05104
      Location:10781225
      Rib_recp_KP_reg; Ribosome receptor lysine/proline rich region
      pfam15304
      Location:11281264
      AKAP2_C; A-kinase anchor protein 2 C-terminus

    RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Rnor_6.0 Primary Assembly

    Genomic

    1. NC_005109.4 Reference Rnor_6.0 Primary Assembly

      Range
      59000400..59010794
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006246802.2XP_006246864.1  myb-binding protein 1A isoform X1

      See identical proteins and their annotated locations for XP_006246864.1

      UniProtKB/Swiss-Prot
      O35821
      Related
      ENSRNOP00000021134.1, ENSRNOT00000021134.3
      Conserved Domains (3) summary
      pfam04931
      Location:70833
      DNA_pol_phi; DNA polymerase phi
      pfam05104
      Location:11451292
      Rib_recp_KP_reg; Ribosome receptor lysine/proline rich region
      pfam15304
      Location:11951331
      AKAP2_C; A-kinase anchor protein 2 C-terminus

    Alternate Rn_Celera

    Genomic

    1. AC_000078.1 Alternate Rn_Celera

      Range
      56183820..56193776
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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