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    evi5b ecotropic viral integration site 5b [ Danio rerio (zebrafish) ]

    Gene ID: 553306, updated on 3-Oct-2019

    Summary

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    Official Symbol
    evi5bprovided by ZNC
    Official Full Name
    ecotropic viral integration site 5bprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-041111-244
    See related
    Ensembl:ENSDARG00000070839
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Cyprinidae; Danio
    Also known as
    evi5; im:7145726; zgc:123024

    Genomic context

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    See evi5b in Genome Data Viewer
    Location:
    chromosome: 6
    Exon count:
    23
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 6 NC_007117.7 (29010374..29085500, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 6 NC_007117.6 (29019813..29095011, complement)
    103 previous assembly Zv9 (GCF_000002035.4) 6 NC_007117.5 (28724170..28799382, complement)

    Chromosome 6 - NC_007117.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC103908735 Neighboring gene uncharacterized LOC101886035 Neighboring gene growth factor independent 1A transcription repressor b Neighboring gene ribosomal protein L5b Neighboring gene divergent protein kinase domain 1Ab

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Pu.1 target gene Zbtb11 regulates neutrophil development through its integrase-like HHCC zinc finger. Keightley MC, et al. Nat Commun, 2017 Apr 6. PMID 28382966, Free PMC Article
    2. Distinct requirements for Wntless in habenular development. Kuan YS, et al. Dev Biol, 2015 Oct 15. PMID 26116173, Free PMC Article
    3. Hematopoietic gene expression profile in zebrafish kidney marrow. Song HD, et al. Proc Natl Acad Sci U S A, 2004 Nov 16. PMID 15520368, Free PMC Article
    4. 15000 unique zebrafish EST clusters and their future use in microarray for profiling gene expression patterns during embryogenesis. Lo J, et al. Genome Res, 2003 Mar. PMID 12618376, Free PMC Article
    5. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article

    See all (8) citations in PubMed

    See citations in PubMed for homologs of this gene provided by HomoloGene

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    • Homologs of the evi5b gene: The evi5b gene is conserved in human, chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, fruit fly, mosquito, C.elegans, A.thaliana, rice, and frog.
    • Orthologs

    Clone Names

    • MGC123024

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    GTPase activator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		 PubMed 
    GTPase activator activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Rab GTPase binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		 PubMed 
    Process Evidence Code Pubs
    activation of GTPase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		 PubMed 
    intracellular protein transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		 PubMed 
    regulation of GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    EVI5-like protein; ecotropic viral integration site 5 protein homolog; ecotropic viral integration site 5 protein; ecotropic viral integration site 5b
    Names
    ecotropic viral integration site 5

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007117.7 Reference GRCz11 Primary Assembly

      Range
      29010374..29085500 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021477143.1 → XP_021332818.1  ecotropic viral integration site 5 protein homolog isoform X4

      Related
      ENSDARP00000106064.2, ENSDART00000124947.3
      Conserved Domains (2) summary
      smart00164
      Location:143 → 351
      TBC; Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs
      cl25732
      Location:388 → 693
      SMC_N; RecF/RecN/SMC N terminal domain

    2. XM_021477142.1 → XP_021332817.1  ecotropic viral integration site 5 protein homolog isoform X3

      Conserved Domains (2) summary
      smart00164
      Location:143 → 351
      TBC; Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs
      cl25732
      Location:389 → 700
      SMC_N; RecF/RecN/SMC N terminal domain

    3. XM_021477139.1 → XP_021332814.1  EVI5-like protein isoform X1

      Conserved Domains (2) summary
      smart00164
      Location:143 → 351
      TBC; Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs
      cl25732
      Location:389 → 718
      SMC_N; RecF/RecN/SMC N terminal domain

    4. XM_021477140.1 → XP_021332815.1  ecotropic viral integration site 5 protein isoform X2

      Conserved Domains (2) summary
      smart00164
      Location:115 → 323
      TBC; Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs
      cl25732
      Location:361 → 690
      SMC_N; RecF/RecN/SMC N terminal domain

    5. XM_021477141.1 → XP_021332816.1  ecotropic viral integration site 5 protein isoform X2

      Conserved Domains (2) summary
      smart00164
      Location:115 → 323
      TBC; Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs
      cl25732
      Location:361 → 690
      SMC_N; RecF/RecN/SMC N terminal domain

    6. XM_021477144.1 → XP_021332819.1  EVI5-like protein isoform X5

      Conserved Domains (2) summary
      smart00164
      Location:143 → 351
      TBC; Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs
      cl25732
      Location:389 → 718
      SMC_N; RecF/RecN/SMC N terminal domain

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018394646.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      414018..495085 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005165960.4 → XP_005166017.2  ecotropic viral integration site 5 protein homolog isoform X4

      Conserved Domains (2) summary
      smart00164
      Location:143 → 351
      TBC; Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs
      cl25732
      Location:388 → 693
      SMC_N; RecF/RecN/SMC N terminal domain

    2. XM_017356628.2 → XP_017212117.2  ecotropic viral integration site 5 protein homolog isoform X3

      Conserved Domains (2) summary
      smart00164
      Location:143 → 351
      TBC; Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs
      cl25732
      Location:389 → 700
      SMC_N; RecF/RecN/SMC N terminal domain

    3. XM_009302431.3 → XP_009300706.2  EVI5-like protein isoform X1

      Conserved Domains (2) summary
      smart00164
      Location:143 → 351
      TBC; Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs
      cl25732
      Location:389 → 718
      SMC_N; RecF/RecN/SMC N terminal domain

    4. XM_009302432.3 → XP_009300707.2  ecotropic viral integration site 5 protein isoform X2

      Conserved Domains (2) summary
      smart00164
      Location:115 → 323
      TBC; Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs
      cl25732
      Location:361 → 690
      SMC_N; RecF/RecN/SMC N terminal domain

    5. XM_009302433.3 → XP_009300708.2  ecotropic viral integration site 5 protein isoform X2

      Conserved Domains (2) summary
      smart00164
      Location:115 → 323
      TBC; Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs
      cl25732
      Location:361 → 690
      SMC_N; RecF/RecN/SMC N terminal domain

    6. XM_021471772.1 → XP_021327447.1  ecotropic viral integration site 5 protein isoform X6

      Conserved Domains (2) summary
      smart00164
      Location:71 → 279
      TBC; Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs
      cl25732
      Location:317 → 646
      SMC_N; RecF/RecN/SMC N terminal domain

    7. XM_009302434.3 → XP_009300709.2  EVI5-like protein isoform X5

      Conserved Domains (2) summary
      smart00164
      Location:143 → 351
      TBC; Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs
      cl25732
      Location:389 → 718
      SMC_N; RecF/RecN/SMC N terminal domain
    Nucleotide Protein Strain
    Heading Accession and Version

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