Format

Send to:

Choose Destination
    • Showing Current items.

    ALAS2 5'-aminolevulinate synthase 2 [ Gallus gallus (chicken) ]

    Gene ID: 552895, updated on 30-Jul-2018
    Symbol
    ALAS2provided by CGNC
    Full Name
    5'-aminolevulinate synthase 2provided by CGNC
    Primary source
    CGNC:2897
    See related
    Ensembl:ENSGALG00000003948
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Also known as
    ALAS1; ALASE; ALASN; ALAS-E
    Orthologs
    See ALAS2 in Genome Data Viewer
    Location:
    chromosome: 12
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    104 current GRCg6a (GCF_000002315.5) 12 NC_006099.5 (3345484..3352330)
    103 previous assembly Gallus_gallus-5.0 (GCF_000002315.4) 12 NC_006099.4 (2927404..2934247)

    Chromosome 12 - NC_006099.5Genomic Context describing neighboring genes Neighboring gene glutamate metabotropic receptor 2 Neighboring gene IQ motif containing F6 Neighboring gene HEAT repeat-containing protein 8-like 3 Neighboring gene twinfilin actin binding protein 2 Neighboring gene protein phosphatase, Mg2+/Mn2+ dependent 1M

    Homology

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    5-aminolevulinate synthase activity TAS
    Traceable Author Statement
    more info
     
    pyridoxal phosphate binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    heme biosynthetic process TAS
    Traceable Author Statement
    more info
     
    protoporphyrinogen IX biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    cytosol TAS
    Traceable Author Statement
    more info
     
    mitochondrial matrix TAS
    Traceable Author Statement
    more info
     
    Preferred Names
    5-aminolevulinate synthase, nonspecific, mitochondrial
    Names
    5'-aminolevulinate synthase 1
    5-aminolevulinate synthase, erythroid-specific, mitochondrial
    5-aminolevulinic acid synthase 1
    5-aminolevulinic acid synthase 2
    ALA-synthase
    ALAS-H
    Delta-ALA synthase 2
    Delta-aminolevulinate synthase 2
    aminolevulinate, delta-, synthase 1
    delta-ALA synthase 1
    delta-aminolevulinate synthase 1
    NP_001018012.1
    XP_025010275.1

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001018012.1NP_001018012.1  5-aminolevulinate synthase, nonspecific, mitochondrial precursor

      See identical proteins and their annotated locations for NP_001018012.1

      Status: PROVISIONAL

      Source sequence(s)
      X02827
      UniProtKB/Swiss-Prot
      P07997
      Related
      ENSGALP00000046192.1, ENSGALT00000061450.2
      Conserved Domains (3) summary
      COG0156
      Location:192589
      BioF; 7-keto-8-aminopelargonate synthetase or related enzyme [Coenzyme transport and metabolism]
      pfam09029
      Location:2131
      Preseq_ALAS; 5-aminolevulinate synthase presequence
      cl18945
      Location:192597
      AAT_I; Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the ...

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 104 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCg6a Primary Assembly

    Genomic

    1. NC_006099.5 Reference GRCg6a Primary Assembly

      Range
      3345484..3352330
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_025154507.1XP_025010275.1  5-aminolevulinate synthase, nonspecific, mitochondrial isoform X1

      Conserved Domains (2) summary
      pfam09029
      Location:2131
      Preseq_ALAS; 5-aminolevulinate synthase presequence
      cl18945
      Location:140545
      AAT_I; Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the ...
    Support Center