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    L1TD1 LINE1 type transposase domain containing 1 [ Homo sapiens (human) ]

    Gene ID: 54596, updated on 6-Sep-2021

    Summary

    Official Symbol
    L1TD1provided by HGNC
    Official Full Name
    LINE1 type transposase domain containing 1provided by HGNC
    Primary source
    HGNC:HGNC:25595
    See related
    Ensembl:ENSG00000240563
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    ECAT11
    Expression
    Biased expression in placenta (RPKM 6.2), testis (RPKM 4.7) and 4 other tissues See more
    Orthologs
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    Genomic context

    See L1TD1 in Genome Data Viewer
    Location:
    1p31.3
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    109.20210514 current GRCh38.p13 (GCF_000001405.39) 1 NC_000001.11 (62194849..62212328)
    105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (62660521..62678000)

    Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene ribosomal protein S15a pseudogene 7 Neighboring gene phosphatidylinositol glycan anchor biosynthesis class P pseudogene 2 Neighboring gene KN motif and ankyrin repeat domains 4 Neighboring gene RNA, U6 small nuclear 371, pseudogene Neighboring gene uncharacterized LOC105378768

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • FLJ10884, MGC133253

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables single-stranded RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in transposition, RNA-mediated IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in intracellular membrane-bounded organelle IDA
    Inferred from Direct Assay
    more info
     
    part_of ribonucleoprotein complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    LINE-1 type transposase domain-containing protein 1
    Names
    ES cell-associated protein 11
    LINE-1 type transposase domain containing 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001164835.2NP_001158307.1  LINE-1 type transposase domain-containing protein 1

      See identical proteins and their annotated locations for NP_001158307.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein.
      Source sequence(s)
      AB211065, AK001973, BU677875, BX382228, CN428323, CX166941, CX167172, DR005055
      Consensus CDS
      CCDS619.1
      UniProtKB/Swiss-Prot
      Q5T7N2
      Conserved Domains (1) summary
      pfam02994
      Location:600863
      Transposase_22; L1 transposable element
    2. NM_019079.5NP_061952.3  LINE-1 type transposase domain-containing protein 1

      See identical proteins and their annotated locations for NP_061952.3

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants 1 and 2 encode the same protein.
      Source sequence(s)
      AB211065, AK001973, BU677875, BX382228, CN428323, CX167172, DR005055
      Consensus CDS
      CCDS619.1
      UniProtKB/Swiss-Prot
      Q5T7N2
      Related
      ENSP00000419901.1, ENST00000498273.2
      Conserved Domains (1) summary
      pfam02994
      Location:600863
      Transposase_22; L1 transposable element

    RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p13 Primary Assembly

    Genomic

    1. NC_000001.11 Reference GRCh38.p13 Primary Assembly

      Range
      62194849..62212328
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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