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    PTK2B protein tyrosine kinase 2 beta [ Bos taurus (cattle) ]

    Gene ID: 541008, updated on 12-Oct-2019

    Summary

    Official Symbol
    PTK2Bprovided by VGNC
    Official Full Name
    protein tyrosine kinase 2 betaprovided by VGNC
    Primary source
    VGNC:VGNC:33519
    See related
    BGD:BT11441; Ensembl:ENSBTAG00000005958
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Also known as
    PYK2
    Orthologs

    Genomic context

    See PTK2B in Genome Data Viewer
    Location:
    chromosome: 8
    Exon count:
    33
    Annotation release Status Assembly Chr Location
    106 current ARS-UCD1.2 (GCF_002263795.1) 8 NC_037335.1 (74417327..74555613)
    105 previous assembly Bos_taurus_UMD_3.1.1 (GCF_000003055.6) 8 AC_000165.1 (75713097..75850444) , (75871043..75871717)

    Chromosome 8 - NC_037335.1Genomic Context describing neighboring genes Neighboring gene stathmin 4 Neighboring gene uncharacterized LOC112447822 Neighboring gene tripartite motif containing 35 Neighboring gene cholinergic receptor nicotinic alpha 2 subunit Neighboring gene epoxide hydrolase 2 Neighboring gene nascent polypeptide-associated complex subunit alpha pseudogene Neighboring gene L-gulono-gamma-lactone oxidase

    Genomic regions, transcripts, and products

    Pathways from BioSystems

    General gene information

    Homology

    Clone Names

    • MGC139227

    General protein information

    Preferred Names
    protein-tyrosine kinase 2-beta
    Names
    PTK2B protein tyrosine kinase 2 beta
    NP_001095722.1
    XP_024851681.1
    XP_024851682.1
    XP_024851683.1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001102252.1NP_001095722.1  protein-tyrosine kinase 2-beta

      See identical proteins and their annotated locations for NP_001095722.1

      Status: PROVISIONAL

      Source sequence(s)
      BC150125
      UniProtKB/TrEMBL
      A6QR59
      Related
      ENSBTAP00000059391.1, ENSBTAT00000084967.1
      Conserved Domains (6) summary
      cd05056
      Location:418687
      PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
      smart00219
      Location:425679
      TyrKc; Tyrosine kinase, catalytic domain
      smart00295
      Location:41254
      B41; Band 4.1 homologues
      cd13190
      Location:261368
      FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
      cd14473
      Location:150254
      FERM_B-lobe; FERM domain B-lobe
      pfam03623
      Location:8721001
      Focal_AT; Focal adhesion targeting region

    RefSeqs of Annotated Genomes: Bos taurus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD1.2 Primary Assembly

    Genomic

    1. NC_037335.1 Reference ARS-UCD1.2 Primary Assembly

      Range
      74417327..74555613
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024995915.1XP_024851683.1  protein-tyrosine kinase 2-beta isoform X3

      Conserved Domains (3) summary
      cd05056
      Location:418687
      PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
      smart00295
      Location:41254
      B41; Band 4.1 homologues
      cd13190
      Location:261368
      FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
    2. XM_024995913.1XP_024851681.1  protein-tyrosine kinase 2-beta isoform X1

      Conserved Domains (4) summary
      cd05056
      Location:418687
      PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
      smart00295
      Location:41254
      B41; Band 4.1 homologues
      cd13190
      Location:261368
      FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
      pfam03623
      Location:8721001
      Focal_AT; Focal adhesion targeting region
    3. XM_024995914.1XP_024851682.1  protein-tyrosine kinase 2-beta isoform X2

      Related
      ENSBTAP00000073091.1, ENSBTAT00000087333.1
      Conserved Domains (4) summary
      cd05056
      Location:418687
      PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
      smart00295
      Location:41254
      B41; Band 4.1 homologues
      cd13190
      Location:261368
      FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
      pfam03623
      Location:830959
      Focal_AT; Focal adhesion targeting region
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