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    HEYL hes related family bHLH transcription factor with YRPW motif-like [ Bos taurus (cattle) ]

    Gene ID: 538609, updated on 27-Aug-2018

    Summary

    Official Symbol
    HEYLprovided by VGNC
    Official Full Name
    hes related family bHLH transcription factor with YRPW motif-likeprovided by VGNC
    Primary source
    VGNC:VGNC:29830
    See related
    BGD:BT23748; Ensembl:ENSBTAG00000008688
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs

    Genomic context

    See HEYL in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    106 current ARS-UCD1.2 (GCF_002263795.1) 3 NC_037330.1 (106442713..106458224)
    105 previous assembly Bos_taurus_UMD_3.1.1 (GCF_000003055.6) 3 AC_000160.1 (107032465..107047976)

    Chromosome 3 - NC_037330.1Genomic Context describing neighboring genes Neighboring gene hippocalcin like 4 Neighboring gene 5'-nucleotidase, cytosolic IA Neighboring gene small nucleolar RNA SNORA55 Neighboring gene poly(A) binding protein cytoplasmic 4 Neighboring gene succinyl-CoA:3-ketoacid coenzyme A transferase 2, mitochondrial Neighboring gene bone morphogenetic protein 8a

    Genomic regions, transcripts, and products

    Pathways from BioSystems

    • Breast cancer, organism-specific biosystem (from KEGG)
      Breast cancer, organism-specific biosystemBreast cancer is the leading cause of cancer death among women worldwide. The vast majority of breast cancers are carcinomas that originate from cells lining the milk-forming ducts of the mammary gla...
    • Breast cancer, conserved biosystem (from KEGG)
      Breast cancer, conserved biosystemBreast cancer is the leading cause of cancer death among women worldwide. The vast majority of breast cancers are carcinomas that originate from cells lining the milk-forming ducts of the mammary gla...

    General gene information

    Homology

    Clone Names

    • MGC134303

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    protein dimerization activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    Notch signaling pathway IEA
    Inferred from Electronic Annotation
    more info
     
    multicellular organism development IEA
    Inferred from Electronic Annotation
    more info
     
    regulation of transcription, DNA-templated IEA
    Inferred from Electronic Annotation
    more info
     
    transcription, DNA-templated IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    hairy/enhancer-of-split related with YRPW motif-like protein

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001024565.2NP_001019736.2  hairy/enhancer-of-split related with YRPW motif-like protein

      See identical proteins and their annotated locations for NP_001019736.2

      Status: PROVISIONAL

      Source sequence(s)
      NKLS02000003
      UniProtKB/TrEMBL
      G3X6Q3
      Related
      ENSBTAP00000011453.4, ENSBTAT00000011453.4
      Conserved Domains (2) summary
      smart00511
      Location:116163
      ORANGE; Orange domain
      cd00083
      Location:45101
      HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...

    RefSeqs of Annotated Genomes: Bos taurus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD1.2 Primary Assembly

    Genomic

    1. NC_037330.1 Reference ARS-UCD1.2 Primary Assembly

      Range
      106442713..106458224
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005204796.1XP_005204853.1  hairy/enhancer-of-split related with YRPW motif-like protein isoform X2

      See identical proteins and their annotated locations for XP_005204853.1

      UniProtKB/Swiss-Prot
      Q2NL18
      Conserved Domains (2) summary
      smart00511
      Location:87134
      ORANGE; Orange domain
      cd00083
      Location:1672
      HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
    2. XM_005204794.4XP_005204851.1  hairy/enhancer-of-split related with YRPW motif-like protein isoform X1

      Conserved Domains (2) summary
      smart00511
      Location:106153
      ORANGE; Orange domain
      cd00083
      Location:3591
      HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
    3. XM_005204795.4XP_005204852.1  hairy/enhancer-of-split related with YRPW motif-like protein isoform X2

      See identical proteins and their annotated locations for XP_005204852.1

      UniProtKB/Swiss-Prot
      Q2NL18
      Conserved Domains (2) summary
      smart00511
      Location:87134
      ORANGE; Orange domain
      cd00083
      Location:1672
      HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
    4. XM_024989590.1XP_024845358.1  hairy/enhancer-of-split related with YRPW motif-like protein isoform X2

      Conserved Domains (2) summary
      smart00511
      Location:87134
      ORANGE; Orange domain
      cd00083
      Location:1672
      HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
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