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    ATG16L1 autophagy related 16 like 1 [ Bos taurus (cattle) ]

    Gene ID: 509587, updated on 27-Aug-2018

    Summary

    Official Symbol
    ATG16L1provided by VGNC
    Official Full Name
    autophagy related 16 like 1provided by VGNC
    Primary source
    VGNC:VGNC:26253
    See related
    BGD:BT16113; Ensembl:ENSBTAG00000003928
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs

    Genomic context

    See ATG16L1 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    106 current ARS-UCD1.2 (GCF_002263795.1) 3 NC_037330.1 (112968429..113012711)
    105 previous assembly Bos_taurus_UMD_3.1.1 (GCF_000003055.6) 3 AC_000160.1 (113578510..113622808)

    Chromosome 3 - NC_037330.1Genomic Context describing neighboring genes Neighboring gene inositol polyphosphate-5-phosphatase D Neighboring gene uncharacterized LOC112445892 Neighboring gene small Cajal body-specific RNA 6 Neighboring gene small Cajal body-specific RNA 6 Neighboring gene S-antigen visual arrestin Neighboring gene diacylglycerol kinase delta Neighboring gene ubiquitin specific peptidase 40

    Genomic regions, transcripts, and products

    Pathways from BioSystems

    • Autophagy - animal, organism-specific biosystem (from KEGG)
      Autophagy - animal, organism-specific biosystemAutophagy (or macroautophagy) is a cellular catabolic pathway involving in protein degradation, organelle turnover, and non-selective breakdown of cytoplasmic components, which is evolutionarily cons...
    • Autophagy - animal, conserved biosystem (from KEGG)
      Autophagy - animal, conserved biosystemAutophagy (or macroautophagy) is a cellular catabolic pathway involving in protein degradation, organelle turnover, and non-selective breakdown of cytoplasmic components, which is evolutionarily cons...
    • Autophagy - other, organism-specific biosystem (from KEGG)
      Autophagy - other, organism-specific biosystemAutophagy is a degradative pathway for the removal of cytoplasmic materials in eukaryotic cells, and is characterized by the formation of a double-membrane structure called the autophagosome, either ...
    • Autophagy - other, conserved biosystem (from KEGG)
      Autophagy - other, conserved biosystemAutophagy is a degradative pathway for the removal of cytoplasmic materials in eukaryotic cells, and is characterized by the formation of a double-membrane structure called the autophagosome, either ...
    • Cellular responses to stress, organism-specific biosystem (from REACTOME)
      Cellular responses to stress, organism-specific biosystemcomputationally inferred pathway (not manually curated)
    • Macroautophagy, organism-specific biosystem (from REACTOME)
      Macroautophagy, organism-specific biosystemcomputationally inferred pathway (not manually curated)
    • NOD-like receptor signaling pathway, organism-specific biosystem (from KEGG)
      NOD-like receptor signaling pathway, organism-specific biosystemSpecific families of pattern recognition receptors are responsible for detecting various pathogens and generating innate immune responses. The intracellular NOD-like receptor (NLR) family contains mo...
    • NOD-like receptor signaling pathway, conserved biosystem (from KEGG)
      NOD-like receptor signaling pathway, conserved biosystemSpecific families of pattern recognition receptors are responsible for detecting various pathogens and generating innate immune responses. The intracellular NOD-like receptor (NLR) family contains mo...
    • Senescence and Autophagy in Cancer, organism-specific biosystem (from WikiPathways)
      Senescence and Autophagy in Cancer, organism-specific biosystemSenescense and Autophagy Pathways in Cancer

    General gene information

    Markers

    Homology

    General protein information

    Preferred Names
    autophagy-related protein 16-1
    Names
    ATG16 autophagy related 16-like 1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001191389.2NP_001178318.1  autophagy-related protein 16-1

      See identical proteins and their annotated locations for NP_001178318.1

      Status: VALIDATED

      Source sequence(s)
      NKLS02000003
      Conserved Domains (4) summary
      cd00200
      Location:317605
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:327364
      7WD40; WD40 repeat [structural motif]
      pfam08614
      Location:31206
      ATG16; Autophagy protein 16 (ATG16)
      cl01837
      Location:212257
      DUF2332; Uncharacterized protein conserved in bacteria (DUF2332)

    RefSeqs of Annotated Genomes: Bos taurus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD1.2 Primary Assembly

    Genomic

    1. NC_037330.1 Reference ARS-UCD1.2 Primary Assembly

      Range
      112968429..113012711
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005204951.4XP_005205008.1  autophagy-related protein 16-1 isoform X2

      See identical proteins and their annotated locations for XP_005205008.1

      Conserved Domains (4) summary
      cd00200
      Location:298586
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:308345
      7WD40; WD40 repeat [structural motif]
      pfam08614
      Location:31206
      ATG16; Autophagy protein 16 (ATG16)
      cl01837
      Location:212269
      DUF2332; Uncharacterized protein conserved in bacteria (DUF2332)
    2. XM_005204950.4XP_005205007.1  autophagy-related protein 16-1 isoform X1

      See identical proteins and their annotated locations for XP_005205007.1

      UniProtKB/TrEMBL
      E1BGS8
      Related
      ENSBTAP00000005131.5
      Conserved Domains (4) summary
      cd00200
      Location:333621
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:343380
      7WD40; WD40 repeat [structural motif]
      pfam08614
      Location:31206
      ATG16; Autophagy protein 16 (ATG16)
      pfam09787
      Location:95336
      Golgin_A5; Golgin subfamily A member 5
    3. XM_010803843.2XP_010802145.1  autophagy-related protein 16-1 isoform X3

      See identical proteins and their annotated locations for XP_010802145.1

      Conserved Domains (6) summary
      COG2319
      Location:247505
      WD40; WD40 repeat [General function prediction only]
      cd00200
      Location:249537
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      pfam07926
      Location:1121
      TPR_MLP1_2; TPR/MLP1/MLP2-like protein
      sd00039
      Location:259296
      7WD40; WD40 repeat [structural motif]
      cl01837
      Location:128173
      DUF2332; Uncharacterized protein conserved in bacteria (DUF2332)
      cl23720
      Location:33138
      RILP-like; Rab interacting lysosomal protein-like 1 and 2 (Rilpl1 and Rilpl2)
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