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    LOC477699 alpha-2-macroglobulin [ Canis lupus familiaris (dog) ]

    Gene ID: 477699, updated on 15-Oct-2019

    Summary

    Gene symbol
    LOC477699
    Gene description
    alpha-2-macroglobulin
    See related
    Ensembl:ENSCAFG00000024781
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Also known as
    A2M

    Genomic context

    See LOC477699 in Genome Data Viewer
    Location:
    chromosome: 27
    Exon count:
    36
    Annotation release Status Assembly Chr Location
    105 current CanFam3.1 (GCF_000002285.3) 27 NC_006609.3 (36654328..36695775)

    Chromosome 27 - NC_006609.3Genomic Context describing neighboring genes Neighboring gene pregnancy zone protein-like Neighboring gene ORM1-like protein 2 pseudogene Neighboring gene pregnancy-zone protein Neighboring gene killer cell lectin like receptor G1 Neighboring gene mannose-6-phosphate receptor, cation dependent

    Genomic regions, transcripts, and products

    Genomic Sequence:
    NC_006609.3 Chromosome 27 Reference CanFam3.1 Primary Assembly

    General gene information

    Homology

    General protein information

    Preferred Names
    alpha-2-macroglobulin-P; alpha-2-macroglobulin

    NCBI Reference Sequences (RefSeq)

    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 105 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference CanFam3.1 Primary Assembly

    Genomic

    1. NC_006609.3 Reference CanFam3.1 Primary Assembly

      Range
      36654328..36695775
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_534893.6XP_534893.3  alpha-2-macroglobulin

      UniProtKB/TrEMBL
      F6UME0
      Related
      ENSCAFP00000020293.3, ENSCAFT00000021846.4
      Conserved Domains (7) summary
      COG2373
      Location:1241072
      YfaS; Uncharacterized conserved protein YfaS, alpha-2-macroglobulin family [General function prediction only]
      cd02897
      Location:9591265
      A2M_2; Proteins similar to alpha2-macroglobulin (alpha (2)-M). This group also contains the pregnancy zone protein (PZP). Alpha(2)-M and PZP are broadly specific proteinase inhibitors. Alpha (2)-M is a major carrier protein in serum. The structural thioester ...
      pfam00207
      Location:741831
      A2M; Alpha-2-macroglobulin family
      pfam01835
      Location:129221
      A2M_N; MG2 domain
      pfam07677
      Location:13771464
      A2M_recep; A-macroglobulin receptor
      pfam07678
      Location:10111267
      A2M_comp; A-macroglobulin complement component
      pfam07703
      Location:461606
      A2M_N_2; Alpha-2-macroglobulin family N-terminal region
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