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    CDK5 cyclin dependent kinase 5 [ Pan troglodytes (chimpanzee) ]

    Gene ID: 463891, updated on 23-Mar-2018

    Summary

    Official Symbol
    CDK5provided by VGNC
    Official Full Name
    cyclin dependent kinase 5provided by VGNC
    Primary source
    VGNC:VGNC:7364
    See related
    Ensembl:ENSPTRG00000019872
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Pan troglodytes
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
    Orthologs

    Genomic context

    See CDK5 in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    105 current Clint_PTRv2 (GCF_002880755.1) 7 NC_036886.1 (147632962..147637110, complement)
    103 previous assembly Pan_troglodytes-2.1.4 (GCF_000001515.6) 7 NC_006474.3 (152214133..152218282, complement)

    Chromosome 7 - NC_036886.1Genomic Context describing neighboring genes Neighboring gene nitric oxide synthase 3 Neighboring gene autophagy related 9B Neighboring gene ATP binding cassette subfamily B member 8 Neighboring gene acid sensing ion channel subunit 3 Neighboring gene solute carrier family 4 member 2 Neighboring gene Fas activated serine/threonine kinase

    Genomic regions, transcripts, and products

    Expression

    • Project title: Tissue-specific RNA-sequencing for ten non-human primate species
    • Description: Total RNA sequencing of fifteen different tissues for ten non-human primates
    • BioProject: PRJNA271912
    • Publication: PMID 25392405
    • Analysis date: Tue Apr 3 07:13:10 2018

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Pathways from BioSystems

    • Alzheimer's disease, organism-specific biosystem (from KEGG)
      Alzheimer's disease, organism-specific biosystemAlzheimer's disease (AD) is a chronic disorder that slowly destroys neurons and causes serious cognitive disability. AD is associated with senile plaques and neurofibrillary tangles (NFTs). Amyloid-b...
    • Alzheimer's disease, conserved biosystem (from KEGG)
      Alzheimer's disease, conserved biosystemAlzheimer's disease (AD) is a chronic disorder that slowly destroys neurons and causes serious cognitive disability. AD is associated with senile plaques and neurofibrillary tangles (NFTs). Amyloid-b...
    • Axon guidance, organism-specific biosystem (from KEGG)
      Axon guidance, organism-specific biosystemAxon guidance represents a key stage in the formation of neuronal network. Axons are guided by a variety of guidance factors, such as netrins, ephrins, Slits, and semaphorins. These guidance cues are...
    • Axon guidance, conserved biosystem (from KEGG)
      Axon guidance, conserved biosystemAxon guidance represents a key stage in the formation of neuronal network. Axons are guided by a variety of guidance factors, such as netrins, ephrins, Slits, and semaphorins. These guidance cues are...
    • Cocaine addiction, organism-specific biosystem (from KEGG)
      Cocaine addiction, organism-specific biosystemDrug addiction is a chronic, relapsing disorder in which compulsive drug-seeking and drug-taking behavior persists despite serious negative consequences.There is strong evidence that the dopaminergic...
    • Cocaine addiction, conserved biosystem (from KEGG)
      Cocaine addiction, conserved biosystemDrug addiction is a chronic, relapsing disorder in which compulsive drug-seeking and drug-taking behavior persists despite serious negative consequences.There is strong evidence that the dopaminergic...

    General gene information

    Markers

    Homology

    General protein information

    Preferred Names
    cyclin-dependent-like kinase 5
    XP_003318964.1
    XP_519523.2

    NCBI Reference Sequences (RefSeq)

    RefSeqs of Annotated Genomes: Pan troglodytes Annotation Release 105 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Clint_PTRv2 Primary Assembly

    Genomic

    1. NC_036886.1 Reference Clint_PTRv2 Primary Assembly

      Range
      147632962..147637110 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_003318916.5XP_003318964.1  cyclin-dependent-like kinase 5 isoform X2

      See identical proteins and their annotated locations for XP_003318964.1

      UniProtKB/TrEMBL
      K7C0V1
      Related
      ENSPTRP00000066042.1
      Conserved Domains (1) summary
      cl21453
      Location:3254
      PKc_like; Protein Kinases, catalytic domain
    2. XM_519523.4XP_519523.2  cyclin-dependent-like kinase 5 isoform X1

      See identical proteins and their annotated locations for XP_519523.2

      UniProtKB/TrEMBL
      H2QVM3
      Related
      ENSPTRP00000034032.4
      Conserved Domains (1) summary
      cd07839
      Location:3286
      STKc_CDK5; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 5
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