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    EPHA5 EPH receptor A5 [ Pan troglodytes (chimpanzee) ]

    Gene ID: 461299, updated on 5-Oct-2018

    Summary

    Official Symbol
    EPHA5provided by VGNC
    Official Full Name
    EPH receptor A5provided by VGNC
    Primary source
    VGNC:VGNC:2035
    Locus tag
    CK820_G0003328
    See related
    Ensembl:ENSPTRG00000016095
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Pan troglodytes
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
    Orthologs

    Genomic context

    See EPHA5 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    105 current Clint_PTRv2 (GCF_002880755.1) 4 NC_036883.1 (63327629..63681658)
    103 previous assembly Pan_troglodytes-2.1.4 (GCF_000001515.6) 4 NC_006471.3 (64277686..64630900)

    Chromosome 4 - NC_036883.1Genomic Context describing neighboring genes Neighboring gene U2 spliceosomal RNA Neighboring gene uncharacterized LOC104006092 Neighboring gene uncharacterized LOC104006093 Neighboring gene 60S ribosomal protein L6-like Neighboring gene arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1 pseudogene Neighboring gene uncharacterized LOC104006095

    Genomic regions, transcripts, and products

    Expression

    • Project title: Tissue-specific RNA-sequencing for ten non-human primate species
    • Description: Total RNA sequencing of fifteen different tissues for ten non-human primates
    • BioProject: PRJNA271912
    • Publication: PMID 25392405
    • Analysis date: Tue Apr 3 07:13:10 2018

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Pathways from BioSystems

    • Axon guidance, organism-specific biosystem (from KEGG)
      Axon guidance, organism-specific biosystemAxon guidance represents a key stage in the formation of neuronal network. Axons are guided by a variety of guidance factors, such as netrins, ephrins, Slits, and semaphorins. These guidance cues are...
    • Axon guidance, conserved biosystem (from KEGG)
      Axon guidance, conserved biosystemAxon guidance represents a key stage in the formation of neuronal network. Axons are guided by a variety of guidance factors, such as netrins, ephrins, Slits, and semaphorins. These guidance cues are...

    General gene information

    Markers

    Homology

    General protein information

    Preferred Names
    ephrin type-A receptor 5
    Names
    ephrin receptor EphA5
    XP_001165182.1
    XP_001165218.1
    XP_009446094.1
    XP_009446095.1
    XP_009446096.1
    XP_009446097.1
    XP_009446098.1
    XP_016807125.1

    NCBI Reference Sequences (RefSeq)

    RefSeqs of Annotated Genomes: Pan troglodytes Annotation Release 105 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Clint_PTRv2 Primary Assembly

    Genomic

    1. NC_036883.1 Reference Clint_PTRv2 Primary Assembly

      Range
      63327629..63681658
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_009447821.3XP_009446096.1  ephrin type-A receptor 5 isoform X6

      Related
      ENSPTRP00000079500.1
      Conserved Domains (7) summary
      cd09546
      Location:854919
      SAM_EPH-A5; SAM domain of EPH-A5 subfamily of tyrosine kinase receptors
      smart00454
      Location:858916
      SAM; Sterile alpha motif
      cd10483
      Location:60232
      EphR_LBD_A5; Ligand Binding Domain of Ephrin type-A Receptor 5
      cd00063
      Location:357447
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd05066
      Location:559825
      PTKc_EphR_A; Catalytic domain of the Protein Tyrosine Kinases, Class EphA Ephrin Receptors
      pfam07714
      Location:564821
      Pkinase_Tyr; Protein tyrosine kinase
      pfam14575
      Location:467559
      EphA2_TM; Ephrin type-A receptor 2 transmembrane domain
    2. XM_009447822.3XP_009446097.1  ephrin type-A receptor 5 isoform X7

      Conserved Domains (6) summary
      cd10483
      Location:60232
      EphR_LBD_A5; Ligand Binding Domain of Ephrin type-A Receptor 5
      cd00063
      Location:357447
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd05066
      Location:558824
      PTKc_EphR_A; Catalytic domain of the Protein Tyrosine Kinases, Class EphA Ephrin Receptors
      pfam07714
      Location:563820
      Pkinase_Tyr; Protein tyrosine kinase
      pfam14575
      Location:466558
      EphA2_TM; Ephrin type-A receptor 2 transmembrane domain
      cl15755
      Location:853891
      SAM_superfamily; SAM (Sterile alpha motif )
    3. XM_009447823.3XP_009446098.1  ephrin type-A receptor 5 isoform X8

      Related
      ENSPTRP00000064078.1
      Conserved Domains (5) summary
      cd09546
      Location:802867
      SAM_EPH-A5; SAM domain of EPH-A5 subfamily of tyrosine kinase receptors
      cd10483
      Location:60232
      EphR_LBD_A5; Ligand Binding Domain of Ephrin type-A Receptor 5
      cd00063
      Location:305395
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd05066
      Location:507773
      PTKc_EphR_A; Catalytic domain of the Protein Tyrosine Kinases, Class EphA Ephrin Receptors
      pfam14575
      Location:415507
      EphA2_TM; Ephrin type-A receptor 2 transmembrane domain
    4. XM_009447819.3XP_009446094.1  ephrin type-A receptor 5 isoform X1

      Related
      ENSPTRP00000027683.5
      Conserved Domains (6) summary
      cd09546
      Location:9661031
      SAM_EPH-A5; SAM domain of EPH-A5 subfamily of tyrosine kinase receptors
      cd10483
      Location:60232
      EphR_LBD_A5; Ligand Binding Domain of Ephrin type-A Receptor 5
      cd00063
      Location:469559
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd05066
      Location:671937
      PTKc_EphR_A; Catalytic domain of the Protein Tyrosine Kinases, Class EphA Ephrin Receptors
      pfam00041
      Location:359447
      fn3; Fibronectin type III domain
      pfam14575
      Location:579671
      EphA2_TM; Ephrin type-A receptor 2 transmembrane domain
    5. XM_009447820.3XP_009446095.1  ephrin type-A receptor 5 isoform X3

      Related
      ENSPTRP00000065630.1
      Conserved Domains (6) summary
      cd09546
      Location:9441009
      SAM_EPH-A5; SAM domain of EPH-A5 subfamily of tyrosine kinase receptors
      cd10483
      Location:60232
      EphR_LBD_A5; Ligand Binding Domain of Ephrin type-A Receptor 5
      cd00063
      Location:469559
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd05066
      Location:649915
      PTKc_EphR_A; Catalytic domain of the Protein Tyrosine Kinases, Class EphA Ephrin Receptors
      pfam00041
      Location:359447
      fn3; Fibronectin type III domain
      pfam14575
      Location:579649
      EphA2_TM; Ephrin type-A receptor 2 transmembrane domain
    6. XM_001165182.5XP_001165182.1  ephrin type-A receptor 5 isoform X2

      UniProtKB/TrEMBL
      H2QPJ1
      Conserved Domains (6) summary
      cd09546
      Location:9651030
      SAM_EPH-A5; SAM domain of EPH-A5 subfamily of tyrosine kinase receptors
      cd10483
      Location:60232
      EphR_LBD_A5; Ligand Binding Domain of Ephrin type-A Receptor 5
      cd00063
      Location:469559
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd05066
      Location:670936
      PTKc_EphR_A; Catalytic domain of the Protein Tyrosine Kinases, Class EphA Ephrin Receptors
      pfam00041
      Location:359447
      fn3; Fibronectin type III domain
      pfam14575
      Location:578670
      EphA2_TM; Ephrin type-A receptor 2 transmembrane domain
    7. XM_001165218.5XP_001165218.1  ephrin type-A receptor 5 isoform X4

      Conserved Domains (6) summary
      cd09546
      Location:9431008
      SAM_EPH-A5; SAM domain of EPH-A5 subfamily of tyrosine kinase receptors
      cd10483
      Location:60232
      EphR_LBD_A5; Ligand Binding Domain of Ephrin type-A Receptor 5
      cd00063
      Location:469559
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd05066
      Location:648914
      PTKc_EphR_A; Catalytic domain of the Protein Tyrosine Kinases, Class EphA Ephrin Receptors
      pfam00041
      Location:359447
      fn3; Fibronectin type III domain
      pfam14575
      Location:578648
      EphA2_TM; Ephrin type-A receptor 2 transmembrane domain
    8. XM_016951636.2XP_016807125.1  ephrin type-A receptor 5 isoform X5

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