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    ACE angiotensin I converting enzyme [ Gallus gallus (chicken) ]

    Gene ID: 419953, updated on 30-Jun-2018
    Official Symbol
    ACEprovided by CGNC
    Official Full Name
    angiotensin I converting enzymeprovided by CGNC
    Primary source
    CGNC:306
    See related
    Ensembl:ENSGALG00000000498
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Also known as
    DCP1
    Orthologs
    See ACE in Genome Data Viewer
    Location:
    chromosome: 27
    Exon count:
    25
    Annotation release Status Assembly Chr Location
    104 current GRCg6a (GCF_000002315.5) 27 NC_006114.5 (5066557..5082805)
    103 previous assembly Gallus_gallus-5.0 (GCF_000002315.4) 27 NC_006114.4 (2830975..2847223)

    Chromosome 27 - NC_006114.5Genomic Context describing neighboring genes Neighboring gene tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 Neighboring gene cytochrome b561 Neighboring gene potassium voltage-gated channel subfamily H member 6 Neighboring gene DDB1 and CUL4 associated factor 7 Neighboring gene mitogen-activated protein kinase kinase kinase 3

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    • ACE Inhibitor Pathway, organism-specific biosystem (from WikiPathways)
      ACE Inhibitor Pathway, organism-specific biosystemThe renin-angiotensin-aldosterone system (RAAS) is central to the control of blood pressure and the target of several types of anti-hypertensive drugs. This pathway depicts a simplified representatio...

    Homology

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    carboxypeptidase activity IEA
    Inferred from Electronic Annotation
    more info
     
    dipeptidyl-peptidase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    dipeptidyl-peptidase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    exopeptidase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    metallopeptidase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    metallopeptidase activity NAS
    Non-traceable Author Statement
    more info
    PubMed 
    peptidyl-dipeptidase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    peptidyl-dipeptidase activity NAS
    Non-traceable Author Statement
    more info
    PubMed 
    zinc ion binding ISA
    Inferred from Sequence Alignment
    more info
    PubMed 
    Process Evidence Code Pubs
    cell proliferation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of blood pressure IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    positive regulation of systemic arterial blood pressure IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    primitive erythrocyte differentiation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    proteolysis IEA
    Inferred from Electronic Annotation
    more info
     
    regulation of systemic arterial blood pressure by renin-angiotensin IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    extracellular space IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    integral component of membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Preferred Names
    angiotensin-converting enzyme
    Names
    angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
    dipeptidyl carboxypeptidase I
    kininase II
    NP_001161204.1

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001167732.1NP_001161204.1  angiotensin-converting enzyme precursor

      See identical proteins and their annotated locations for NP_001161204.1

      Status: VALIDATED

      Source sequence(s)
      AADN05000732
      UniProtKB/TrEMBL
      F1NYM0
      Related
      ENSGALP00000039731.2, ENSGALT00000040528.2
      Conserved Domains (1) summary
      pfam01401
      Location:6291207
      Peptidase_M2; Angiotensin-converting enzyme

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 104 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCg6a Primary Assembly

    Genomic

    1. NC_006114.5 Reference GRCg6a Primary Assembly

      Range
      5066557..5082805
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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