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    Cln3 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 39981, updated on 8-Oct-2018

    Summary

    Official Symbol
    Cln3provided by FlyBase
    Primary source
    FLYBASE:FBgn0036756
    Locus tag
    Dmel_CG5582
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster (old-lineage: Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG5582; cln3; CLN3; Dmel\CG5582

    Genomic context

    See Cln3 in Genome Data Viewer
    Location:
    75A2-75A2; 3-45 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    Release 6.13 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (17809231..17814119, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (17802331..17807219, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Ionotropic receptor 75a Neighboring gene Ionotropic receptor 75b

    Genomic regions, transcripts, and products

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Pathways from BioSystems

    • Lysosome, organism-specific biosystem (from KEGG)
      Lysosome, organism-specific biosystemLysosomes are membrane-delimited organelles in animal cells serving as the cell's main digestive compartment to which all sorts of macromolecules are delivered for degradation. They contain more than...
    • Lysosome, conserved biosystem (from KEGG)
      Lysosome, conserved biosystemLysosomes are membrane-delimited organelles in animal cells serving as the cell's main digestive compartment to which all sorts of macromolecules are delivered for degradation. They contain more than...

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    arginine transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    determination of adult lifespan IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    lysosome organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    regulation of JNK cascade IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of Notch signaling pathway IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of intracellular pH IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    response to oxidative stress IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    apical plasma membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    late endosome IDA
    Inferred from Direct Assay
    more info
    PubMed 
    lysosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    lysosome IDA
    Inferred from Direct Assay
    more info
    PubMed 
    microvillus membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    mitochondrial membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    vesicle IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    Cln3
    Names
    CG5582-PA
    CG5582-PB
    Cln3-PA
    Cln3-PB
    ceroid-lipofuscinosis, neuronal 3
    cln3

    NCBI Reference Sequences (RefSeq)

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      17809231..17814119 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_140754.2NP_649011.1  Cln3, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_649011.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VVL0
      Related
      FBpp0074933, FBtr0075167
      Conserved Domains (1) summary
      pfam02487
      Location:40413
      CLN3; CLN3 protein
    2. NM_001275070.1NP_001261999.1  Cln3, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001261999.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VVL0
      Related
      FBpp0305846, FBtr0333693
      Conserved Domains (1) summary
      pfam02487
      Location:40413
      CLN3; CLN3 protein
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